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Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange.

Smirnovas V, Baron GS, Offerdahl DK, Raymond GJ, Caughey B, Surewicz WK.

Nat Struct Mol Biol. 2011 Apr;18(4):504-6. doi: 10.1038/nsmb.2035. Epub 2011 Mar 27.


Crucial role for prion protein membrane anchoring in the neuroinvasion and neural spread of prion infection.

Klingeborn M, Race B, Meade-White KD, Rosenke R, Striebel JF, Chesebro B.

J Virol. 2011 Feb;85(4):1484-94. doi: 10.1128/JVI.02167-10. Epub 2010 Dec 1.


Generation of antisera to purified prions in lipid rafts.

Hnasko R, Serban AV, Carlson G, Prusiner SB, Stanker LH.

Prion. 2010 Apr-Jun;4(2):94-104. Epub 2010 Apr 9. Erratum in: Prion. 2011 Jul-Sep;5(3):235.


Comparative profiling of highly enriched 22L and Chandler mouse scrapie prion protein preparations.

Moore RA, Timmes A, Wilmarth PA, Priola SA.

Proteomics. 2010 Aug;10(15):2858-69. doi: 10.1002/pmic.201000104.


Fatal transmissible amyloid encephalopathy: a new type of prion disease associated with lack of prion protein membrane anchoring.

Chesebro B, Race B, Meade-White K, Lacasse R, Race R, Klingeborn M, Striebel J, Dorward D, McGovern G, Jeffrey M.

PLoS Pathog. 2010 Mar 5;6(3):e1000800. doi: 10.1371/journal.ppat.1000800.


Glycosylation of PrPC determines timing of neuroinvasion and targeting in the brain following transmissible spongiform encephalopathy infection by a peripheral route.

Cancellotti E, Bradford BM, Tuzi NL, Hickey RD, Brown D, Brown KL, Barron RM, Kisielewski D, Piccardo P, Manson JC.

J Virol. 2010 Apr;84(7):3464-75. doi: 10.1128/JVI.02374-09. Epub 2010 Jan 27.


Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.

Lee S, Antony L, Hartmann R, Knaus KJ, Surewicz K, Surewicz WK, Yee VC.

EMBO J. 2010 Jan 6;29(1):251-62. doi: 10.1038/emboj.2009.333. Epub 2009 Nov 19.


Prion protein glycosylation is not required for strain-specific neurotropism.

Piro JR, Harris BT, Nishina K, Soto C, Morales R, Rees JR, Supattapone S.

J Virol. 2009 Jun;83(11):5321-8. doi: 10.1128/JVI.02502-08. Epub 2009 Mar 18.


Detection of prion infectivity in fat tissues of scrapie-infected mice.

Race B, Meade-White K, Oldstone MB, Race R, Chesebro B.

PLoS Pathog. 2008 Dec;4(12):e1000232. doi: 10.1371/journal.ppat.1000232. Epub 2008 Dec 5.


Isolation at physiological temperature of detergent-resistant membranes with properties expected of lipid rafts: the influence of buffer composition.

Chen X, Jen A, Warley A, Lawrence MJ, Quinn PJ, Morris RJ.

Biochem J. 2009 Jan 15;417(2):525-33. doi: 10.1042/BJ20081385.


Host PrP glycosylation: a major factor determining the outcome of prion infection.

Tuzi NL, Cancellotti E, Baybutt H, Blackford L, Bradford B, Plinston C, Coghill A, Hart P, Piccardo P, Barron RM, Manson JC.

PLoS Biol. 2008 Apr 15;6(4):e100. doi: 10.1371/journal.pbio.0060100.


Ultrastructures and strain comparison of under-glycosylated scrapie prion fibrils.

Sim VL, Caughey B.

Neurobiol Aging. 2009 Dec;30(12):2031-42. doi: 10.1016/j.neurobiolaging.2008.02.016. Epub 2008 Apr 3.


Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking.

Atarashi R, Wilham JM, Christensen L, Hughson AG, Moore RA, Johnson LM, Onwubiko HA, Priola SA, Caughey B.

Nat Methods. 2008 Mar;5(3):211-2. doi: 10.1038/nmeth0308-211. No abstract available.


Electron crystallography of the scrapie prion protein complexed with heavy metals.

Wille H, Govaerts C, Borovinskiy A, Latawiec D, Downing KH, Cohen FE, Prusiner SB.

Arch Biochem Biophys. 2007 Nov 15;467(2):239-48. Epub 2007 Aug 23.


Analytical applications of Fourier transform-infrared (FT-IR) spectroscopy in microbiology and prion research.

Beekes M, Lasch P, Naumann D.

Vet Microbiol. 2007 Aug 31;123(4):305-19. Epub 2007 Apr 8. Review.


Comparative studies on the thermostability of five strains of transmissible-spongiform-encephalopathy agent.

Fernie K, Steele PJ, Taylor DM, Somerville RA.

Biotechnol Appl Biochem. 2007 Aug;47(Pt 4):175-83.


Prion strain-dependent differences in conversion of mutant prion proteins in cell culture.

Atarashi R, Sim VL, Nishida N, Caughey B, Katamine S.

J Virol. 2006 Aug;80(16):7854-62.


Structural differences between TSEs strains investigated by FT-IR spectroscopy.

Spassov S, Beekes M, Naumann D.

Biochim Biophys Acta. 2006 Jul;1760(7):1138-49. Epub 2006 Mar 27.


Anchorless prion protein results in infectious amyloid disease without clinical scrapie.

Chesebro B, Trifilo M, Race R, Meade-White K, Teng C, LaCasse R, Raymond L, Favara C, Baron G, Priola S, Caughey B, Masliah E, Oldstone M.

Science. 2005 Jun 3;308(5727):1435-9.


Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine.

Mishra RS, Basu S, Gu Y, Luo X, Zou WQ, Mishra R, Li R, Chen SG, Gambetti P, Fujioka H, Singh N.

J Neurosci. 2004 Dec 15;24(50):11280-90.

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