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PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90.

LaFayette SL, Collins C, Zaas AK, Schell WA, Betancourt-Quiroz M, Gunatilaka AA, Perfect JR, Cowen LE.

PLoS Pathog. 2010 Aug 26;6(8):e1001069. doi: 10.1371/journal.ppat.1001069.


Differential filamentation of Candida albicans and Candida dubliniensis Is governed by nutrient regulation of UME6 expression.

O'Connor L, Caplice N, Coleman DC, Sullivan DJ, Moran GP.

Eukaryot Cell. 2010 Sep;9(9):1383-97. doi: 10.1128/EC.00042-10. Epub 2010 Jul 16.


Development and validation of an in vivo Candida albicans biofilm denture model.

Nett JE, Marchillo K, Spiegel CA, Andes DR.

Infect Immun. 2010 Sep;78(9):3650-9. doi: 10.1128/IAI.00480-10. Epub 2010 Jul 6.


Distributions and antifungal susceptibility of Candida species from mucosal sites in HIV positive patients.

Badiee P, Alborzi A, Davarpanah MA, Shakiba E.

Arch Iran Med. 2010 Jul;13(4):282-7. doi: 010134/AIM.006.


Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity.

Noble SM, French S, Kohn LA, Chen V, Johnson AD.

Nat Genet. 2010 Jul;42(7):590-8. doi: 10.1038/ng.605. Epub 2010 Jun 13.


Calcineurin regulates innate antifungal immunity in neutrophils.

Greenblatt MB, Aliprantis A, Hu B, Glimcher LH.

J Exp Med. 2010 May 10;207(5):923-31. doi: 10.1084/jem.20092531. Epub 2010 Apr 26.


Oropharyngeal candidiasis in the era of antiretroviral therapy.

Thompson GR 3rd, Patel PK, Kirkpatrick WR, Westbrook SD, Berg D, Erlandsen J, Redding SW, Patterson TF.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Apr;109(4):488-95. doi: 10.1016/j.tripleo.2009.11.026. Epub 2010 Feb 13. Review.


Phosphatidylserine synthase and phosphatidylserine decarboxylase are essential for cell wall integrity and virulence in Candida albicans.

Chen YL, Montedonico AE, Kauffman S, Dunlap JR, Menn FM, Reynolds TB.

Mol Microbiol. 2010 Mar;75(5):1112-32. doi: 10.1111/j.1365-2958.2009.07018.x. Epub 2010 Feb 4.


Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata.

Miyazaki T, Yamauchi S, Inamine T, Nagayoshi Y, Saijo T, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Kohno S.

Antimicrob Agents Chemother. 2010 Apr;54(4):1639-43. doi: 10.1128/AAC.01364-09. Epub 2010 Jan 25.


Comparative transcript profiling of Candida albicans and Candida dubliniensis identifies SFL2, a C. albicans gene required for virulence in a reconstituted epithelial infection model.

Spiering MJ, Moran GP, Chauvel M, Maccallum DM, Higgins J, Hokamp K, Yeomans T, d'Enfert C, Coleman DC, Sullivan DJ.

Eukaryot Cell. 2010 Feb;9(2):251-65. doi: 10.1128/EC.00291-09. Epub 2009 Dec 18.


Caspofungin-non-susceptible Candida isolates in cancer patients.

Kofteridis DP, Lewis RE, Kontoyiannis DP.

J Antimicrob Chemother. 2010 Feb;65(2):293-5. doi: 10.1093/jac/dkp444. Epub 2009 Dec 16.


Detection and antifungal susceptibility testing of oral Candida dubliniensis from human immunodeficiency virus-infected patients.

Chunchanur SK, Nadgir SD, Halesh LH, Patil BS, Kausar Y, Chandrasekhar MR.

Indian J Pathol Microbiol. 2009 Oct-Dec;52(4):501-4. doi: 10.4103/0377-4929.56138.


Genetic differences between avian and human isolates of Candida dubliniensis.

McManus BA, Sullivan DJ, Moran GP, d'Enfert C, Bougnoux ME, Nunn MA, Coleman DC.

Emerg Infect Dis. 2009 Sep;15(9):1467-70. doi: 10.3201/eid1509.081660.


Fungal echinocandin resistance.

Walker LA, Gow NA, Munro CA.

Fungal Genet Biol. 2010 Feb;47(2):117-26. doi: 10.1016/j.fgb.2009.09.003. Epub 2009 Sep 19.


Comparative genomics of the fungal pathogens Candida dubliniensis and Candida albicans.

Jackson AP, Gamble JA, Yeomans T, Moran GP, Saunders D, Harris D, Aslett M, Barrell JF, Butler G, Citiulo F, Coleman DC, de Groot PW, Goodwin TJ, Quail MA, McQuillan J, Munro CA, Pain A, Poulter RT, Rajandream MA, Renauld H, Spiering MJ, Tivey A, Gow NA, Barrell B, Sullivan DJ, Berriman M.

Genome Res. 2009 Dec;19(12):2231-44. doi: 10.1101/gr.097501.109. Epub 2009 Sep 10.


Calcineurin is an antagonist to PKA protein phosphorylation required for postmating filamentation and virulence, while PP2A is required for viability in Ustilago maydis.

Egan JD, García-Pedrajas MD, Andrews DL, Gold SE.

Mol Plant Microbe Interact. 2009 Oct;22(10):1293-301. doi: 10.1094/MPMI-22-10-1293.


Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin.

Singh SD, Robbins N, Zaas AK, Schell WA, Perfect JR, Cowen LE.

PLoS Pathog. 2009 Jul;5(7):e1000532. doi: 10.1371/journal.ppat.1000532. Epub 2009 Jul 31.


Mechanisms of hypha orientation of fungi.

Brand A, Gow NA.

Curr Opin Microbiol. 2009 Aug;12(4):350-7. doi: 10.1016/j.mib.2009.05.007. Epub 2009 Jun 21. Review.


Isolation of Candida dubliniensis from denture wearers.

Gasparoto TH, Dionísio TJ, de Oliveira CE, Porto VC, Gelani V, Santos CF, Campanelli AP, Lara VS.

J Med Microbiol. 2009 Jul;58(Pt 7):959-62. doi: 10.1099/jmm.0.008391-0. Epub 2009 Jun 4.


Genome-wide gene expression profiling and a forward genetic screen show that differential expression of the sodium ion transporter Ena21 contributes to the differential tolerance of Candida albicans and Candida dubliniensis to osmotic stress.

Enjalbert B, Moran GP, Vaughan C, Yeomans T, Maccallum DM, Quinn J, Coleman DC, Brown AJ, Sullivan DJ.

Mol Microbiol. 2009 Apr;72(1):216-28. doi: 10.1111/j.1365-2958.2009.06640.x. Epub 2009 Feb 23.

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