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Items: 1 to 20 of 37

1.

Unifying Biological Image Formats with HDF5.

Dougherty MT, Folk MJ, Zadok E, Bernstein HJ, Bernstein FC, Eliceiri KW, Benger W, Best C.

Commun ACM. 2009 Oct 1;52(10):42-47. No abstract available.

2.

Dissecting variability in responses to cancer chemotherapy through systems pharmacology.

Yang R, Niepel M, Mitchison TK, Sorger PK.

Clin Pharmacol Ther. 2010 Jul;88(1):34-8. doi: 10.1038/clpt.2010.96. Epub 2010 Jun 2. Review.

3.

Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes.

Alexopoulos LG, Saez-Rodriguez J, Cosgrove BD, Lauffenburger DA, Sorger PK.

Mol Cell Proteomics. 2010 Sep;9(9):1849-65. doi: 10.1074/mcp.M110.000406. Epub 2010 May 10.

4.

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations.

Sharma SV, Lee DY, Li B, Quinlan MP, Takahashi F, Maheswaran S, McDermott U, Azizian N, Zou L, Fischbach MA, Wong KK, Brandstetter K, Wittner B, Ramaswamy S, Classon M, Settleman J.

Cell. 2010 Apr 2;141(1):69-80. doi: 10.1016/j.cell.2010.02.027.

5.

Visualization of omics data for systems biology.

Gehlenborg N, O'Donoghue SI, Baliga NS, Goesmann A, Hibbs MA, Kitano H, Kohlbacher O, Neuweger H, Schneider R, Tenenbaum D, Gavin AC.

Nat Methods. 2010 Mar;7(3 Suppl):S56-68. doi: 10.1038/nmeth.1436. Review.

PMID:
20195258
6.

Automated microscopy for high-content RNAi screening.

Conrad C, Gerlich DW.

J Cell Biol. 2010 Feb 22;188(4):453-61. doi: 10.1083/jcb.200910105. Review.

7.

Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

Turke AB, Zejnullahu K, Wu YL, Song Y, Dias-Santagata D, Lifshits E, Toschi L, Rogers A, Mok T, Sequist L, Lindeman NI, Murphy C, Akhavanfard S, Yeap BY, Xiao Y, Capelletti M, Iafrate AJ, Lee C, Christensen JG, Engelman JA, Jänne PA.

Cancer Cell. 2010 Jan 19;17(1):77-88. doi: 10.1016/j.ccr.2009.11.022.

8.

DataPflex: a MATLAB-based tool for the manipulation and visualization of multidimensional datasets.

Hendriks BS, Espelin CW.

Bioinformatics. 2010 Feb 1;26(3):432-3. doi: 10.1093/bioinformatics/btp667. Epub 2009 Dec 4.

PMID:
19965880
9.

Non-genetic cell-to-cell variability and the consequences for pharmacology.

Niepel M, Spencer SL, Sorger PK.

Curr Opin Chem Biol. 2009 Dec;13(5-6):556-61. doi: 10.1016/j.cbpa.2009.09.015. Epub 2009 Oct 14. Review.

10.

Cancer stem cells: mirage or reality?

Gupta PB, Chaffer CL, Weinberg RA.

Nat Med. 2009 Sep;15(9):1010-2. doi: 10.1038/nm0909-1010. Epub 2009 Sep 4. Review.

PMID:
19734877
11.

Population context determines cell-to-cell variability in endocytosis and virus infection.

Snijder B, Sacher R, Rämö P, Damm EM, Liberali P, Pelkmans L.

Nature. 2009 Sep 24;461(7263):520-3. doi: 10.1038/nature08282. Epub 2009 Aug 26.

PMID:
19710653
12.

Dissecting protein function and signaling using protein microarrays.

Wolf-Yadlin A, Sevecka M, MacBeath G.

Curr Opin Chem Biol. 2009 Oct;13(4):398-405. doi: 10.1016/j.cbpa.2009.06.027. Epub 2009 Aug 5. Review.

13.

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis.

Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK.

Nature. 2009 May 21;459(7245):428-32. doi: 10.1038/nature08012. Epub 2009 Apr 12.

14.

Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data.

Chen WW, Schoeberl B, Jasper PJ, Niepel M, Nielsen UB, Lauffenburger DA, Sorger PK.

Mol Syst Biol. 2009;5:239. doi: 10.1038/msb.2008.74. Epub 2009 Jan 20.

15.

Variability and robustness in T cell activation from regulated heterogeneity in protein levels.

Feinerman O, Veiga J, Dorfman JR, Germain RN, Altan-Bonnet G.

Science. 2008 Aug 22;321(5892):1081-4. doi: 10.1126/science.1158013.

16.

Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project.

Taylor CF, Field D, Sansone SA, Aerts J, Apweiler R, Ashburner M, Ball CA, Binz PA, Bogue M, Booth T, Brazma A, Brinkman RR, Michael Clark A, Deutsch EW, Fiehn O, Fostel J, Ghazal P, Gibson F, Gray T, Grimes G, Hancock JM, Hardy NW, Hermjakob H, Julian RK Jr, Kane M, Kettner C, Kinsinger C, Kolker E, Kuiper M, Le Novère N, Leebens-Mack J, Lewis SE, Lord P, Mallon AM, Marthandan N, Masuya H, McNally R, Mehrle A, Morrison N, Orchard S, Quackenbush J, Reecy JM, Robertson DG, Rocca-Serra P, Rodriguez H, Rosenfelder H, Santoyo-Lopez J, Scheuermann RH, Schober D, Smith B, Snape J, Stoeckert CJ Jr, Tipton K, Sterk P, Untergasser A, Vandesompele J, Wiemann S.

Nat Biotechnol. 2008 Aug;26(8):889-96. doi: 10.1038/nbt.1411. No abstract available.

17.

EGFR antagonists in cancer treatment.

Ciardiello F, Tortora G.

N Engl J Med. 2008 Mar 13;358(11):1160-74. doi: 10.1056/NEJMra0707704. Review. No abstract available. Erratum in: N Engl J Med. 2009 Apr 9;360(15):1579.

PMID:
18337605
18.

Flexible informatics for linking experimental data to mathematical models via DataRail.

Saez-Rodriguez J, Goldsipe A, Muhlich J, Alexopoulos LG, Millard B, Lauffenburger DA, Sorger PK.

Bioinformatics. 2008 Mar 15;24(6):840-7. doi: 10.1093/bioinformatics/btn018. Epub 2008 Jan 24.

19.

High-content single-cell drug screening with phosphospecific flow cytometry.

Krutzik PO, Crane JM, Clutter MR, Nolan GP.

Nat Chem Biol. 2008 Feb;4(2):132-42. Epub 2007 Dec 23.

PMID:
18157122
20.

Open tools for storage and management of quantitative image data.

Moore J, Allan C, Burel JM, Loranger B, MacDonald D, Monk J, Swedlow JR.

Methods Cell Biol. 2008;85:555-70.

PMID:
18155479

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