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Toward fulfilling the promise of molecular medicine in fragile X syndrome.

Krueger DD, Bear MF.

Annu Rev Med. 2011;62:411-29. doi: 10.1146/annurev-med-061109-134644. Review.


Premutation CGG-repeat expansion of the Fmr1 gene impairs mouse neocortical development.

Cunningham CL, Martínez Cerdeño V, Navarro Porras E, Prakash AN, Angelastro JM, Willemsen R, Hagerman PJ, Pessah IN, Berman RF, Noctor SC.

Hum Mol Genet. 2011 Jan 1;20(1):64-79. doi: 10.1093/hmg/ddq432.


Functional convergence of developmentally and adult-generated granule cells in dentate gyrus circuits supporting hippocampus-dependent memory.

Stone SS, Teixeira CM, Zaslavsky K, Wheeler AL, Martinez-Canabal A, Wang AH, Sakaguchi M, Lozano AM, Frankland PW.

Hippocampus. 2011 Dec;21(12):1348-62. doi: 10.1002/hipo.20845.


Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells.

Ables JL, Decarolis NA, Johnson MA, Rivera PD, Gao Z, Cooper DC, Radtke F, Hsieh J, Eisch AJ.

J Neurosci. 2010 Aug 4;30(31):10484-92. doi: 10.1523/JNEUROSCI.4721-09.2010.


MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1.

Smrt RD, Szulwach KE, Pfeiffer RL, Li X, Guo W, Pathania M, Teng ZQ, Luo Y, Peng J, Bordey A, Jin P, Zhao X.

Stem Cells. 2010 Jun;28(6):1060-70. doi: 10.1002/stem.431.


Adult neurogenesis: integrating theories and separating functions.

Aimone JB, Deng W, Gage FH.

Trends Cogn Sci. 2010 Jul;14(7):325-37. doi: 10.1016/j.tics.2010.04.003. Review.


Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation.

Liu C, Teng ZQ, Santistevan NJ, Szulwach KE, Guo W, Jin P, Zhao X.

Cell Stem Cell. 2010 May 7;6(5):433-44. doi: 10.1016/j.stem.2010.02.017.


Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells.

Luo Y, Shan G, Guo W, Smrt RD, Johnson EB, Li X, Pfeiffer RL, Szulwach KE, Duan R, Barkho BZ, Li W, Liu C, Jin P, Zhao X.

PLoS Genet. 2010 Apr 8;6(4):e1000898. doi: 10.1371/journal.pgen.1000898.


New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

Deng W, Aimone JB, Gage FH.

Nat Rev Neurosci. 2010 May;11(5):339-50. doi: 10.1038/nrn2822. Review.


Running enhances spatial pattern separation in mice.

Creer DJ, Romberg C, Saksida LM, van Praag H, Bussey TJ.

Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2367-72. doi: 10.1073/pnas.0911725107.


Fragile X mental retardation protein in learning-related synaptic plasticity.

Mercaldo V, Descalzi G, Zhuo M.

Mol Cells. 2009 Dec 31;28(6):501-7. doi: 10.1007/s10059-009-0193-x. Review.


Trace and contextual fear conditioning is enhanced in mice lacking the alpha4 subunit of the GABA(A) receptor.

Moore MD, Cushman J, Chandra D, Homanics GE, Olsen RW, Fanselow MS.

Neurobiol Learn Mem. 2010 Mar;93(3):383-7. doi: 10.1016/j.nlm.2009.12.004.


Gene, brain, and behavior relationships in fragile X syndrome: evidence from neuroimaging studies.

Lightbody AA, Reiss AL.

Dev Disabil Res Rev. 2009;15(4):343-52. doi: 10.1002/ddrr.77. Review.


Adult neurogenesis modulates the hippocampus-dependent period of associative fear memory.

Kitamura T, Saitoh Y, Takashima N, Murayama A, Niibori Y, Ageta H, Sekiguchi M, Sugiyama H, Inokuchi K.

Cell. 2009 Nov 13;139(4):814-27. doi: 10.1016/j.cell.2009.10.020.


Argonaute2 suppresses Drosophila fragile X expression preventing neurogenesis and oogenesis defects.

Pepper AS, Beerman RW, Bhogal B, Jongens TA.

PLoS One. 2009 Oct 27;4(10):e7618. doi: 10.1371/journal.pone.0007618.


Adult-born hippocampal dentate granule cells undergoing maturation modulate learning and memory in the brain.

Deng W, Saxe MD, Gallina IS, Gage FH.

J Neurosci. 2009 Oct 28;29(43):13532-42. doi: 10.1523/JNEUROSCI.3362-09.2009.


Learning deficits in C57BL/6J mice following perinatal arsenic exposure: consequence of lower corticosterone receptor levels?

Martinez-Finley EJ, Ali AM, Allan AM.

Pharmacol Biochem Behav. 2009 Dec;94(2):271-7. doi: 10.1016/j.pbb.2009.09.006.


Fmr1 knockout mice show reduced anxiety and alterations in neurogenesis that are specific to the ventral dentate gyrus.

Eadie BD, Zhang WN, Boehme F, Gil-Mohapel J, Kainer L, Simpson JM, Christie BR.

Neurobiol Dis. 2009 Nov;36(2):361-73. doi: 10.1016/j.nbd.2009.08.001.


A functional role for adult hippocampal neurogenesis in spatial pattern separation.

Clelland CD, Choi M, Romberg C, Clemenson GD Jr, Fragniere A, Tyers P, Jessberger S, Saksida LM, Barker RA, Gage FH, Bussey TJ.

Science. 2009 Jul 10;325(5937):210-3. doi: 10.1126/science.1173215.


Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function.

Bassell GJ, Warren ST.

Neuron. 2008 Oct 23;60(2):201-14. doi: 10.1016/j.neuron.2008.10.004. Review.

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