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Items: 10


Granulin is a soluble cofactor for toll-like receptor 9 signaling.

Park B, Buti L, Lee S, Matsuwaki T, Spooner E, Brinkmann MM, Nishihara M, Ploegh HL.

Immunity. 2011 Apr 22;34(4):505-13. doi: 10.1016/j.immuni.2011.01.018.


Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.

Hu F, Padukkavidana T, Vægter CB, Brady OA, Zheng Y, Mackenzie IR, Feldman HH, Nykjaer A, Strittmatter SM.

Neuron. 2010 Nov 18;68(4):654-67. doi: 10.1016/j.neuron.2010.09.034.


Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells.

Blasius AL, Arnold CN, Georgel P, Rutschmann S, Xia Y, Lin P, Ross C, Li X, Smart NG, Beutler B.

Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19973-8. doi: 10.1073/pnas.1014051107.


Golgi-to-phagosome transport of acid sphingomyelinase and prosaposin is mediated by sortilin.

Wähe A, Kasmapour B, Schmaderer C, Liebl D, Sandhoff K, Nykjaer A, Griffiths G, Gutierrez MG.

J Cell Sci. 2010 Jul 15;123(Pt 14):2502-11. doi: 10.1242/jcs.067686.


Intracellular toll-like receptors.

Blasius AL, Beutler B.

Immunity. 2010 Mar 26;32(3):305-15. doi: 10.1016/j.immuni.2010.03.012. Review.


Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice.

Yin F, Banerjee R, Thomas B, Zhou P, Qian L, Jia T, Ma X, Ma Y, Iadecola C, Beal MF, Nathan C, Ding A.

J Exp Med. 2010 Jan 18;207(1):117-28. doi: 10.1084/jem.20091568.


The granulin gene family: from cancer to dementia.

Bateman A, Bennett HP.

Bioessays. 2009 Nov;31(11):1245-54. doi: 10.1002/bies.200900086. Review.


Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities.

Tolkatchev D, Malik S, Vinogradova A, Wang P, Chen Z, Xu P, Bennett HP, Bateman A, Ni F.

Protein Sci. 2008 Apr;17(4):711-24. doi: 10.1110/ps.073295308.


A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.

Ivanov S, Dragoi AM, Wang X, Dallacosta C, Louten J, Musco G, Sitia G, Yap GS, Wan Y, Biron CA, Bianchi ME, Wang H, Chu WM.

Blood. 2007 Sep 15;110(6):1970-81.


Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair.

Zhu J, Nathan C, Jin W, Sim D, Ashcroft GS, Wahl SM, Lacomis L, Erdjument-Bromage H, Tempst P, Wright CD, Ding A.

Cell. 2002 Dec 13;111(6):867-78.

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