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Items: 1 to 20 of 121

1.

Designing PEGylated therapeutic molecules: advantages in ADMET properties.

Hamidi M, Rafiei P, Azadi A.

Expert Opin Drug Discov. 2008 Nov;3(11):1293-307. doi: 10.1517/17460441.3.11.1293.

PMID:
23496167
2.

Subcellular targeting strategies for drug design and delivery.

Rajendran L, Knölker HJ, Simons K.

Nat Rev Drug Discov. 2010 Jan;9(1):29-42. doi: 10.1038/nrd2897. Review.

PMID:
20043027
3.

Therapeutic potential of RNA interference in drug-resistant cancers.

Lage H.

Future Oncol. 2009 Mar;5(2):169-85. doi: 10.2217/14796694.5.2.169. Review.

PMID:
19284376
4.
5.

Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice.

Judge AD, Robbins M, Tavakoli I, Levi J, Hu L, Fronda A, Ambegia E, McClintock K, MacLachlan I.

J Clin Invest. 2009 Mar;119(3):661-73. doi: 10.1172/JCI37515. Epub 2009 Feb 23.

6.

Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer.

Saad M, Garbuzenko OB, Minko T.

Nanomedicine (Lond). 2008 Dec;3(6):761-76. doi: 10.2217/17435889.3.6.761.

7.

Tumour hypoxia affects the responsiveness of cancer cells to chemotherapy and promotes cancer progression.

Cosse JP, Michiels C.

Anticancer Agents Med Chem. 2008 Oct;8(7):790-7. Review.

PMID:
18855580
8.

Hydrogel nanoparticles in drug delivery.

Hamidi M, Azadi A, Rafiei P.

Adv Drug Deliv Rev. 2008 Dec 14;60(15):1638-49. doi: 10.1016/j.addr.2008.08.002. Epub 2008 Sep 20. Review.

PMID:
18840488
9.

In vivo reversal of P-glycoprotein-mediated multidrug resistance by efficient delivery of stealth RNAi.

Xiao H, Wu Z, Shen H, Luo AL, Yang YF, Li XB, Zhu DY.

Basic Clin Pharmacol Toxicol. 2008 Oct;103(4):342-8. doi: 10.1111/j.1742-7843.2008.00296.x.

11.

Cancer cell metabolism: Warburg and beyond.

Hsu PP, Sabatini DM.

Cell. 2008 Sep 5;134(5):703-7. doi: 10.1016/j.cell.2008.08.021.

12.

Nanoparticle therapeutics: an emerging treatment modality for cancer.

Davis ME, Chen ZG, Shin DM.

Nat Rev Drug Discov. 2008 Sep;7(9):771-82. doi: 10.1038/nrd2614. Review.

PMID:
18758474
13.

Transcriptional responses to intermittent hypoxia.

Nanduri J, Yuan G, Kumar GK, Semenza GL, Prabhakar NR.

Respir Physiol Neurobiol. 2008 Dec 10;164(1-2):277-81. doi: 10.1016/j.resp.2008.07.006. Review.

14.

Evaluations of combination MDR-1 gene silencing and paclitaxel administration in biodegradable polymeric nanoparticle formulations to overcome multidrug resistance in cancer cells.

Yadav S, van Vlerken LE, Little SR, Amiji MM.

Cancer Chemother Pharmacol. 2009 Mar;63(4):711-22. doi: 10.1007/s00280-008-0790-y. Epub 2008 Jul 11.

PMID:
18618115
15.

Biodistribution and pharmacokinetic analysis of Paclitaxel and ceramide administered in multifunctional polymer-blend nanoparticles in drug resistant breast cancer model.

van Vlerken LE, Duan Z, Little SR, Seiden MV, Amiji MM.

Mol Pharm. 2008 Jul-Aug;5(4):516-26. doi: 10.1021/mp800030k. Epub 2008 Jul 11.

16.

Multi-functional nanocarriers to overcome tumor drug resistance.

Jabr-Milane LS, van Vlerken LE, Yadav S, Amiji MM.

Cancer Treat Rev. 2008 Nov;34(7):592-602. doi: 10.1016/j.ctrv.2008.04.003. Epub 2008 Jun 5. Review.

17.

Hypoxia-inducible factor 1 and cancer pathogenesis.

Semenza GL.

IUBMB Life. 2008 Sep;60(9):591-7. doi: 10.1002/iub.93. Review.

18.

Modulation of drug resistance in ovarian adenocarcinoma by enhancing intracellular ceramide using tamoxifen-loaded biodegradable polymeric nanoparticles.

Devalapally H, Duan Z, Seiden MV, Amiji MM.

Clin Cancer Res. 2008 May 15;14(10):3193-203. doi: 10.1158/1078-0432.CCR-07-4973.

19.

The warburg effect: why and how do cancer cells activate glycolysis in the presence of oxygen?

López-Lázaro M.

Anticancer Agents Med Chem. 2008 Apr;8(3):305-12. Review.

PMID:
18393789
20.

Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF).

Han ZB, Ren H, Zhao H, Chi Y, Chen K, Zhou B, Liu YJ, Zhang L, Xu B, Liu B, Yang R, Han ZC.

Carcinogenesis. 2008 Oct;29(10):1853-61. doi: 10.1093/carcin/bgn066. Epub 2008 Mar 13.

PMID:
18339685

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