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Items: 1 to 20 of 32

1.

MAPKAP kinases MK2 and MK3 in inflammation: complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin.

Ronkina N, Menon MB, Schwermann J, Tiedje C, Hitti E, Kotlyarov A, Gaestel M.

Biochem Pharmacol. 2010 Dec 15;80(12):1915-20. doi: 10.1016/j.bcp.2010.06.021. Epub 2010 Jun 23. Review.

PMID:
20599781
2.

Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment.

Pietrangelo A.

Gastroenterology. 2010 Aug;139(2):393-408, 408.e1-2. doi: 10.1053/j.gastro.2010.06.013. Epub 2010 Jun 11. Review.

PMID:
20542038
3.

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors.

Kawai T, Akira S.

Nat Immunol. 2010 May;11(5):373-84. doi: 10.1038/ni.1863. Epub 2010 Apr 20. Review.

PMID:
20404851
4.

TRIF signaling stimulates translation of TNF-alpha mRNA via prolonged activation of MK2.

Gais P, Tiedje C, Altmayr F, Gaestel M, Weighardt H, Holzmann B.

J Immunol. 2010 May 15;184(10):5842-8. doi: 10.4049/jimmunol.0902456. Epub 2010 Apr 7.

5.

Pattern recognition receptors and inflammation.

Takeuchi O, Akira S.

Cell. 2010 Mar 19;140(6):805-20. doi: 10.1016/j.cell.2010.01.022. Review.

6.

Transcriptional control of the TNF gene.

Falvo JV, Tsytsykova AV, Goldfeld AE.

Curr Dir Autoimmun. 2010;11:27-60. doi: 10.1159/000289196. Epub 2010 Feb 18. Review.

7.

Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines.

Tseng PH, Matsuzawa A, Zhang W, Mino T, Vignali DA, Karin M.

Nat Immunol. 2010 Jan;11(1):70-5. doi: 10.1038/ni.1819. Epub 2009 Nov 8.

8.

Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice.

Wang L, Harrington L, Trebicka E, Shi HN, Kagan JC, Hong CC, Lin HY, Babitt JL, Cherayil BJ.

J Clin Invest. 2009 Nov;119(11):3322-8. doi: 10.1172/JCI39939. Epub 2009 Oct 5.

9.

Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins.

Carpenter S, O'Neill LA.

Biochem J. 2009 Jul 29;422(1):1-10. doi: 10.1042/BJ20090616. Review.

PMID:
19627256
10.

Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation.

Wang L, Johnson EE, Shi HN, Walker WA, Wessling-Resnick M, Cherayil BJ.

J Immunol. 2008 Aug 15;181(4):2723-31.

11.

Post-transcriptional control of cytokine production.

Anderson P.

Nat Immunol. 2008 Apr;9(4):353-9. doi: 10.1038/ni1584. Review.

PMID:
18349815
12.

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta.

Kagan JC, Su T, Horng T, Chow A, Akira S, Medzhitov R.

Nat Immunol. 2008 Apr;9(4):361-8. doi: 10.1038/ni1569. Epub 2008 Feb 24.

13.

The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling.

Sheedy FJ, O'Neill LA.

J Leukoc Biol. 2007 Aug;82(2):196-203. Epub 2007 Apr 20. Review.

PMID:
17449723
14.
15.

Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.

McGettrick AF, Brint EK, Palsson-McDermott EM, Rowe DC, Golenbock DT, Gay NJ, Fitzgerald KA, O'Neill LA.

Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9196-201. Epub 2006 Jun 6.

16.

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.

Rowe DC, McGettrick AF, Latz E, Monks BG, Gay NJ, Yamamoto M, Akira S, O'Neill LA, Fitzgerald KA, Golenbock DT.

Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6299-304. Epub 2006 Apr 7.

17.

Achieving stability of lipopolysaccharide-induced NF-kappaB activation.

Covert MW, Leung TH, Gaston JE, Baltimore D.

Science. 2005 Sep 16;309(5742):1854-7.

18.

CD14 is required for MyD88-independent LPS signaling.

Jiang Z, Georgel P, Du X, Shamel L, Sovath S, Mudd S, Huber M, Kalis C, Keck S, Galanos C, Freudenberg M, Beutler B.

Nat Immunol. 2005 Jun;6(6):565-70. Epub 2005 May 15.

PMID:
15895089
19.

Toll-like receptors are temporally involved in host defense.

Weiss DS, Raupach B, Takeda K, Akira S, Zychlinsky A.

J Immunol. 2004 Apr 1;172(7):4463-9.

20.

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway.

Yamamoto M, Sato S, Hemmi H, Uematsu S, Hoshino K, Kaisho T, Takeuchi O, Takeda K, Akira S.

Nat Immunol. 2003 Nov;4(11):1144-50. Epub 2003 Oct 12.

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