Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 57


Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota.

Kirouac KN, Ling H.

Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3210-5. doi: 10.1073/pnas.1013909108.


DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase.

Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK.

J Mol Biol. 2011 Feb 11;406(1):18-28. doi: 10.1016/j.jmb.2010.12.016.


Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase η.

Silverstein TD, Jain R, Johnson RE, Prakash L, Prakash S, Aggarwal AK.

Structure. 2010 Nov 10;18(11):1463-70. doi: 10.1016/j.str.2010.08.019.


Metal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 from Sulfolobus solfataricus.

Irimia A, Loukachevitch LV, Eoff RL, Guengerich FP, Egli M.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):1013-8. doi: 10.1107/S1744309110029374.


Structure and mechanism of human DNA polymerase eta.

Biertümpfel C, Zhao Y, Kondo Y, Ramón-Maiques S, Gregory M, Lee JY, Masutani C, Lehmann AR, Hanaoka F, Yang W.

Nature. 2010 Jun 24;465(7301):1044-8. doi: 10.1038/nature09196. Erratum in: Nature. 2011 Aug 18;476(7360):360.


Structural basis for the suppression of skin cancers by DNA polymerase eta.

Silverstein TD, Johnson RE, Jain R, Prakash L, Prakash S, Aggarwal AK.

Nature. 2010 Jun 24;465(7301):1039-43. doi: 10.1038/nature09104.


Mutagenic conformation of 8-oxo-7,8-dihydro-2'-dGTP in the confines of a DNA polymerase active site.

Batra VK, Beard WA, Hou EW, Pedersen LC, Prasad R, Wilson SH.

Nat Struct Mol Biol. 2010 Jul;17(7):889-90. doi: 10.1038/nsmb.1852.


Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .

Beckman J, Wang M, Blaha G, Wang J, Konigsberg WH.

Biochemistry. 2010 May 18;49(19):4116-25. doi: 10.1021/bi100102s.


Replication through an abasic DNA lesion: structural basis for adenine selectivity.

Obeid S, Blatter N, Kranaster R, Schnur A, Diederichs K, Welte W, Marx A.

EMBO J. 2010 May 19;29(10):1738-47. doi: 10.1038/emboj.2010.64.


Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69.

Hogg M, Rudnicki J, Midkiff J, Reha-Krantz L, Doublié S, Wallace SS.

Biochemistry. 2010 Mar 23;49(11):2317-25. doi: 10.1021/bi901488d.


Structural insight into translesion synthesis by DNA Pol II.

Wang F, Yang W.

Cell. 2009 Dec 24;139(7):1279-89. doi: 10.1016/j.cell.2009.11.043.


DNA polymerase beta substrate specificity: side chain modulation of the "A-rule".

Beard WA, Shock DD, Batra VK, Pedersen LC, Wilson SH.

J Biol Chem. 2009 Nov 13;284(46):31680-9. doi: 10.1074/jbc.M109.029843.


Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion.

Vasquez-Del Carpio R, Silverstein TD, Lone S, Swan MK, Choudhury JR, Johnson RE, Prakash S, Prakash L, Aggarwal AK.

PLoS One. 2009 Jun 2;4(6):e5766. doi: 10.1371/journal.pone.0005766.


DNA synthesis across an abasic lesion by human DNA polymerase iota.

Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK.

Structure. 2009 Apr 15;17(4):530-7. doi: 10.1016/j.str.2009.02.015.


Y-family DNA polymerases in mammalian cells.

Guo C, Kosarek-Stancel JN, Tang TS, Friedberg EC.

Cell Mol Life Sci. 2009 Jul;66(14):2363-81. doi: 10.1007/s00018-009-0024-4. Review.


Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance.

Waters LS, Minesinger BK, Wiltrout ME, D'Souza S, Woodruff RV, Walker GC.

Microbiol Mol Biol Rev. 2009 Mar;73(1):134-54. doi: 10.1128/MMBR.00034-08. Review.


DNA polymerases and human disease.

Loeb LA, Monnat RJ Jr.

Nat Rev Genet. 2008 Aug;9(8):594-604. doi: 10.1038/nrg2345. Review.


Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation.

Batra VK, Beard WA, Shock DD, Pedersen LC, Wilson SH.

Mol Cell. 2008 May 9;30(3):315-24. doi: 10.1016/j.molcel.2008.02.025.

Items per page

Supplemental Content

Support Center