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Items: 1 to 20 of 55

1.

Essential role of monocytes and macrophages in the progression of acute pancreatitis.

Shrivastava P, Bhatia M.

World J Gastroenterol. 2010 Aug 28;16(32):3995-4002. Review.

2.

Matrix metalloproteinases: regulators of the tumor microenvironment.

Kessenbrock K, Plaks V, Werb Z.

Cell. 2010 Apr 2;141(1):52-67. doi: 10.1016/j.cell.2010.03.015. Review.

3.

Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression.

Littlepage LE, Sternlicht MD, Rougier N, Phillips J, Gallo E, Yu Y, Williams K, Brenot A, Gordon JI, Werb Z.

Cancer Res. 2010 Mar 15;70(6):2224-34. doi: 10.1158/0008-5472.CAN-09-3515. Epub 2010 Mar 9.

4.

Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice.

Morris JP 4th, Cano DA, Sekine S, Wang SC, Hebrok M.

J Clin Invest. 2010 Feb;120(2):508-20. doi: 10.1172/JCI40045. Epub 2010 Jan 11.

5.

The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors.

Hedvat M, Huszar D, Herrmann A, Gozgit JM, Schroeder A, Sheehy A, Buettner R, Proia D, Kowolik CM, Xin H, Armstrong B, Bebernitz G, Weng S, Wang L, Ye M, McEachern K, Chen H, Morosini D, Bell K, Alimzhanov M, Ioannidis S, McCoon P, Cao ZA, Yu H, Jove R, Zinda M.

Cancer Cell. 2009 Dec 8;16(6):487-97. doi: 10.1016/j.ccr.2009.10.015.

6.

STATs in cancer inflammation and immunity: a leading role for STAT3.

Yu H, Pardoll D, Jove R.

Nat Rev Cancer. 2009 Nov;9(11):798-809. doi: 10.1038/nrc2734. Review.

7.

Epidemiology of pancreatic cancer: an overview.

Raimondi S, Maisonneuve P, Lowenfels AB.

Nat Rev Gastroenterol Hepatol. 2009 Dec;6(12):699-708. doi: 10.1038/nrgastro.2009.177. Epub 2009 Oct 6. Review.

PMID:
19806144
8.

Natural history of acute pancreatitis: a long-term population-based study.

Lankisch PG, Breuer N, Bruns A, Weber-Dany B, Lowenfels AB, Maisonneuve P.

Am J Gastroenterol. 2009 Nov;104(11):2797-805; quiz 2806. doi: 10.1038/ajg.2009.405. Epub 2009 Jul 14.

PMID:
19603011
9.

The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma.

Martínez-Romero C, Rooman I, Skoudy A, Guerra C, Molero X, González A, Iglesias M, Lobato T, Bosch A, Barbacid M, Real FX, Hernández-Muñoz I.

J Pathol. 2009 Oct;219(2):205-13. doi: 10.1002/path.2585.

PMID:
19585519
10.

Ras activity levels control the development of pancreatic diseases.

Ji B, Tsou L, Wang H, Gaiser S, Chang DZ, Daniluk J, Bi Y, Grote T, Longnecker DS, Logsdon CD.

Gastroenterology. 2009 Sep;137(3):1072-82, 1082.e1-6. doi: 10.1053/j.gastro.2009.05.052. Epub 2009 Jun 6. Erratum in: Gastroenterology. 2011 May;140(5):1696.

11.

Notch and Kras in pancreatic cancer: at the crossroads of mutation, differentiation and signaling.

De La O JP, Murtaugh LC.

Cell Cycle. 2009 Jun 15;8(12):1860-4. Epub 2009 Jun 15.

12.

Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras.

Carrière C, Young AL, Gunn JR, Longnecker DS, Korc M.

Biochem Biophys Res Commun. 2009 May 8;382(3):561-5. doi: 10.1016/j.bbrc.2009.03.068. Epub 2009 Mar 16.

13.

The STAT3 inhibitor NSC 74859 is effective in hepatocellular cancers with disrupted TGF-beta signaling.

Lin L, Amin R, Gallicano GI, Glasgow E, Jogunoori W, Jessup JM, Zasloff M, Marshall JL, Shetty K, Johnson L, Mishra L, He AR.

Oncogene. 2009 Feb 19;28(7):961-72. doi: 10.1038/onc.2008.448. Epub 2009 Jan 12.

14.

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia.

De La O JP, Emerson LL, Goodman JL, Froebe SC, Illum BE, Curtis AB, Murtaugh LC.

Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18907-12. doi: 10.1073/pnas.0810111105. Epub 2008 Nov 21.

15.

Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice.

Habbe N, Shi G, Meguid RA, Fendrich V, Esni F, Chen H, Feldmann G, Stoffers DA, Konieczny SF, Leach SD, Maitra A.

Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18913-8. doi: 10.1073/pnas.0810097105. Epub 2008 Nov 21.

16.

Overexpression of interleukin-1beta in the murine pancreas results in chronic pancreatitis.

Marrache F, Tu SP, Bhagat G, Pendyala S, Osterreicher CH, Gordon S, Ramanathan V, Penz-Osterreicher M, Betz KS, Song Z, Wang TC.

Gastroenterology. 2008 Oct;135(4):1277-87. doi: 10.1053/j.gastro.2008.06.078. Epub 2008 Jul 1.

17.

Hedgehog signaling is required for effective regeneration of exocrine pancreas.

Fendrich V, Esni F, Garay MV, Feldmann G, Habbe N, Jensen JN, Dor Y, Stoffers D, Jensen J, Leach SD, Maitra A.

Gastroenterology. 2008 Aug;135(2):621-31. doi: 10.1053/j.gastro.2008.04.011. Epub 2008 Apr 16.

18.

STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.

Ernst M, Najdovska M, Grail D, Lundgren-May T, Buchert M, Tye H, Matthews VB, Armes J, Bhathal PS, Hughes NR, Marcusson EG, Karras JG, Na S, Sedgwick JD, Hertzog PJ, Jenkins BJ.

J Clin Invest. 2008 May;118(5):1727-38. doi: 10.1172/JCI34944.

19.

HER2-dependent MMP-7 expression is mediated by activated STAT3.

Yuan G, Qian L, Shi M, Lu F, Li D, Hu M, Yu M, Shen B, Guo N.

Cell Signal. 2008 Jul;20(7):1284-91. doi: 10.1016/j.cellsig.2008.02.017. Epub 2008 Mar 4.

PMID:
18411043
20.

Notch signaling is required for exocrine regeneration after acute pancreatitis.

Siveke JT, Lubeseder-Martellato C, Lee M, Mazur PK, Nakhai H, Radtke F, Schmid RM.

Gastroenterology. 2008 Feb;134(2):544-55. doi: 10.1053/j.gastro.2007.11.003. Epub 2007 Nov 4.

PMID:
18242220

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