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Immune responses against a liver-stage malaria antigen induced by simian adenoviral vector AdCh63 and MVA prime-boost immunisation in non-human primates.

Capone S, Reyes-Sandoval A, Naddeo M, Siani L, Ammendola V, Rollier CS, Nicosia A, Colloca S, Cortese R, Folgori A, Hill AV.

Vaccine. 2010 Dec 16;29(2):256-65. doi: 10.1016/j.vaccine.2010.10.041. Epub 2010 Oct 26.


Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non human primates.

Tewari K, Flynn BJ, Boscardin SB, Kastenmueller K, Salazar AM, Anderson CA, Soundarapandian V, Ahumada A, Keler T, Hoffman SL, Nussenzweig MC, Steinman RM, Seder RA.

Vaccine. 2010 Oct 21;28(45):7256-66. doi: 10.1016/j.vaccine.2010.08.098. Epub 2010 Sep 21.


Interferon-γ--central mediator of protective immune responses against the pre-erythrocytic and blood stage of malaria.

McCall MB, Sauerwein RW.

J Leukoc Biol. 2010 Dec;88(6):1131-43. doi: 10.1189/jlb.0310137. Epub 2010 Jul 7. Review.


Cross-talk between T cells and NK cells generates rapid effector responses to Plasmodium falciparum-infected erythrocytes.

Horowitz A, Newman KC, Evans JH, Korbel DS, Davis DM, Riley EM.

J Immunol. 2010 Jun 1;184(11):6043-52. doi: 10.4049/jimmunol.1000106. Epub 2010 Apr 28.


Chronic intestinal helminth infections are associated with immune hyporesponsiveness and induction of a regulatory network.

Figueiredo CA, Barreto ML, Rodrigues LC, Cooper PJ, Silva NB, Amorim LD, Alcantara-Neves NM.

Infect Immun. 2010 Jul;78(7):3160-7. doi: 10.1128/IAI.01228-09. Epub 2010 Apr 19.


At homeostasis filarial infections have expanded adaptive T regulatory but not classical Th2 cells.

Metenou S, Dembele B, Konate S, Dolo H, Coulibaly SY, Coulibaly YI, Diallo AA, Soumaoro L, Coulibaly ME, Sanogo D, Doumbia SS, Traoré SF, Mahanty S, Klion A, Nutman TB.

J Immunol. 2010 May 1;184(9):5375-82. doi: 10.4049/jimmunol.0904067. Epub 2010 Mar 31.


Regulatory T cells in human geohelminth infection suppress immune responses to BCG and Plasmodium falciparum.

Wammes LJ, Hamid F, Wiria AE, de Gier B, Sartono E, Maizels RM, Luty AJ, Fillié Y, Brice GT, Supali T, Smits HH, Yazdanbakhsh M.

Eur J Immunol. 2010 Feb;40(2):437-42. doi: 10.1002/eji.200939699.


Early interferon-gamma response against Plasmodium falciparum correlates with interethnic differences in susceptibility to parasitemia between sympatric Fulani and Dogon in Mali.

McCall MB, Hopman J, Daou M, Maiga B, Dara V, Ploemen I, Nganou-Makamdop K, Niangaly A, Tolo Y, Arama C, Bousema JT, van der Meer JW, van der Ven AJ, Troye-Blomberg M, Dolo A, Doumbo OK, Sauerwein RW.

J Infect Dis. 2010 Jan 1;201(1):142-52. doi: 10.1086/648596.


Prime-boost immunization with adenoviral and modified vaccinia virus Ankara vectors enhances the durability and polyfunctionality of protective malaria CD8+ T-cell responses.

Reyes-Sandoval A, Berthoud T, Alder N, Siani L, Gilbert SC, Nicosia A, Colloca S, Cortese R, Hill AV.

Infect Immun. 2010 Jan;78(1):145-53. doi: 10.1128/IAI.00740-09. Epub 2009 Oct 26. Erratum in: Infect Immun. 2011 May;79(5):2131.


Neglected tropical diseases in sub-saharan Africa: review of their prevalence, distribution, and disease burden.

Hotez PJ, Kamath A.

PLoS Negl Trop Dis. 2009 Aug 25;3(8):e412. doi: 10.1371/journal.pntd.0000412.


Protection against a malaria challenge by sporozoite inoculation.

Roestenberg M, McCall M, Hopman J, Wiersma J, Luty AJ, van Gemert GJ, van de Vegte-Bolmer M, van Schaijk B, Teelen K, Arens T, Spaarman L, de Mast Q, Roeffen W, Snounou G, Rénia L, van der Ven A, Hermsen CC, Sauerwein R.

N Engl J Med. 2009 Jul 30;361(5):468-77. doi: 10.1056/NEJMoa0805832.


Quality and vaccine efficacy of CD4+ T cell responses directed to dominant and subdominant epitopes in ESAT-6 from Mycobacterium tuberculosis.

Aagaard CS, Hoang TT, Vingsbo-Lundberg C, Dietrich J, Andersen P.

J Immunol. 2009 Aug 15;183(4):2659-68. doi: 10.4049/jimmunol.0900947. Epub 2009 Jul 20.


Patent filarial infection modulates malaria-specific type 1 cytokine responses in an IL-10-dependent manner in a filaria/malaria-coinfected population.

Metenou S, Dembélé B, Konate S, Dolo H, Coulibaly SY, Coulibaly YI, Diallo AA, Soumaoro L, Coulibaly ME, Sanogo D, Doumbia SS, Wagner M, Traoré SF, Klion A, Mahanty S, Nutman TB.

J Immunol. 2009 Jul 15;183(2):916-24. doi: 10.4049/jimmunol.0900257. Epub 2009 Jun 26.


Protection and polyfunctional T cells induced by Ag85B-TB10.4/IC31 against Mycobacterium tuberculosis is highly dependent on the antigen dose.

Aagaard C, Hoang TT, Izzo A, Billeskov R, Troudt J, Arnett K, Keyser A, Elvang T, Andersen P, Dietrich J.

PLoS One. 2009 Jun 16;4(6):e5930. doi: 10.1371/journal.pone.0005930.


Human type 1 and 17 responses in latent tuberculosis are modulated by coincident filarial infection through cytotoxic T lymphocyte antigen-4 and programmed death-1.

Babu S, Bhat SQ, Kumar NP, Jayantasri S, Rukmani S, Kumaran P, Gopi PG, Kolappan C, Kumaraswami V, Nutman TB.

J Infect Dis. 2009 Jul 15;200(2):288-98. doi: 10.1086/599797.


Flow cytometry and the future of vaccine development.

Bolton DL, Roederer M.

Expert Rev Vaccines. 2009 Jun;8(6):779-89. doi: 10.1586/erv.09.41. Review.


Responses to malarial antigens are altered in helminth-infected children.

Hartgers FC, Obeng BB, Kruize YC, Dijkhuis A, McCall M, Sauerwein RW, Luty AJ, Boakye DA, Yazdanbakhsh M.

J Infect Dis. 2009 May 15;199(10):1528-35. doi: 10.1086/598687.


Cellular tumor necrosis factor, gamma interferon, and interleukin-6 responses as correlates of immunity and risk of clinical Plasmodium falciparum malaria in children from Papua New Guinea.

Robinson LJ, D'Ombrain MC, Stanisic DI, Taraika J, Bernard N, Richards JS, Beeson JG, Tavul L, Michon P, Mueller I, Schofield L.

Infect Immun. 2009 Jul;77(7):3033-43. doi: 10.1128/IAI.00211-09. Epub 2009 Apr 20.


Early production of gamma-interferon in clinical malaria: role of interleukin-18 and interleukin-12.

Torre D.

Clin Infect Dis. 2009 May 15;48(10):1481-2. doi: 10.1086/598508. No abstract available.


Potency assays for novel T-cell-inducing vaccines against malaria.

Reyes-Sandoval A, Pearson FE, Todryk S, Ewer K.

Curr Opin Mol Ther. 2009 Feb;11(1):72-80. Review.


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