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Items: 1 to 20 of 37


The origins and evolution of the p53 family of genes.

Belyi VA, Ak P, Markert E, Wang H, Hu W, Puzio-Kuter A, Levine AJ.

Cold Spring Harb Perspect Biol. 2010 Jun;2(6):a001198. doi: 10.1101/cshperspect.a001198. Epub 2009 Dec 16. Review.


p63 and p73, the ancestors of p53.

Dötsch V, Bernassola F, Coutandin D, Candi E, Melino G.

Cold Spring Harb Perspect Biol. 2010 Sep;2(9):a004887. doi: 10.1101/cshperspect.a004887. Epub 2010 May 19. Review.


p53 Research: the past thirty years and the next thirty years.

Lane D, Levine A.

Cold Spring Harb Perspect Biol. 2010 Dec;2(12):a000893. doi: 10.1101/cshperspect.a000893. Epub 2010 May 12. Review.


The role of p53 gene family in reproduction.

Hu W.

Cold Spring Harb Perspect Biol. 2009 Dec;1(6):a001073. doi: 10.1101/cshperspect.a001073. Epub 2009 Oct 28. Review.


The origin of pre-eclampsia: from decidual "hyperoxia" to late hypoxia.

Tranquilli AL, Landi B.

Med Hypotheses. 2010 Jul;75(1):38-46. doi: 10.1016/j.mehy.2010.01.024. Epub 2010 Feb 18.


Uterine-specific p53 deficiency confers premature uterine senescence and promotes preterm birth in mice.

Hirota Y, Daikoku T, Tranguch S, Xie H, Bradshaw HB, Dey SK.

J Clin Invest. 2010 Mar;120(3):803-15. doi: 10.1172/JCI40051.


Differential levels of transcription of p53-regulated genes by the arginine/proline polymorphism: p53 with arginine at codon 72 favors apoptosis.

Jeong BS, Hu W, Belyi V, Rabadan R, Levine AJ.

FASEB J. 2010 May;24(5):1347-53. doi: 10.1096/fj.09-146001. Epub 2009 Dec 17.


Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death.

Gonfloni S, Di Tella L, Caldarola S, Cannata SM, Klinger FG, Di Bartolomeo C, Mattei M, Candi E, De Felici M, Melino G, Cesareni G.

Nat Med. 2009 Oct;15(10):1179-85. doi: 10.1038/nm.2033. Epub 2009 Sep 27.


Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene.

Atwal GS, Kirchhoff T, Bond EE, Montagna M, Menin C, Bertorelle R, Scaini MC, Bartel F, Böhnke A, Pempe C, Gradhand E, Hauptmann S, Offit K, Levine AJ, Bond GL.

Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10236-41. doi: 10.1073/pnas.0901298106. Epub 2009 Jun 4. Erratum in: Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12208. Monagna, Marco [corrected to Montagna, Marco].


Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans.

Kang HJ, Feng Z, Sun Y, Atwal G, Murphy ME, Rebbeck TR, Rosenwaks Z, Levine AJ, Hu W.

Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9761-6. doi: 10.1073/pnas.0904280106. Epub 2009 May 22.


TAp73alpha binds the kinetochore proteins Bub1 and Bub3 resulting in polyploidy.

Vernole P, Neale MH, Barcaroli D, Munarriz E, Knight RA, Tomasini R, Mak TW, Melino G, De Laurenzi V.

Cell Cycle. 2009 Feb 1;8(3):421-9. Epub 2009 Feb 12.


TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity.

Tomasini R, Tsuchihara K, Tsuda C, Lau SK, Wilhelm M, Ruffini A, Tsao MS, Iovanna JL, Jurisicova A, Melino G, Mak TW.

Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):797-802. doi: 10.1073/pnas.0812096106. Epub 2009 Jan 12.


TAp73 knockout shows genomic instability with infertility and tumor suppressor functions.

Tomasini R, Tsuchihara K, Wilhelm M, Fujitani M, Rufini A, Cheung CC, Khan F, Itie-Youten A, Wakeham A, Tsao MS, Iovanna JL, Squire J, Jurisica I, Kaplan D, Melino G, Jurisicova A, Mak TW.

Genes Dev. 2008 Oct 1;22(19):2677-91. doi: 10.1101/gad.1695308. Epub 2008 Sep 19.


p53 regulates maternal reproduction through LIF.

Hu W, Feng Z, Teresky AK, Levine AJ.

Nature. 2007 Nov 29;450(7170):721-4.


Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72.

Reinbold M, Luo JL, Nedelko T, Jerchow B, Murphy ME, Whibley C, Wei Q, Hollstein M.

Oncogene. 2008 Apr 24;27(19):2788-94. Epub 2007 Nov 12.


The impact of leukemia inhibitory factor in uterine flushing on the reproductive potential of infertile women--a prospective study.

Mikolajczyk M, Wirstlein P, Skrzypczak J.

Am J Reprod Immunol. 2007 Jul;58(1):65-74.


Haplotype structure and selection of the MDM2 oncogene in humans.

Atwal GS, Bond GL, Metsuyanim S, Papa M, Friedman E, Distelman-Menachem T, Ben Asher E, Lancet D, Ross DA, Sninsky J, White TJ, Levine AJ, Yarden R.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4524-9. Epub 2007 Mar 5.


p63 protects the female germ line during meiotic arrest.

Suh EK, Yang A, Kettenbach A, Bamberger C, Michaelis AH, Zhu Z, Elvin JA, Bronson RT, Crum CP, McKeon F.

Nature. 2006 Nov 30;444(7119):624-8. Epub 2006 Nov 22.


Polymorphic variants in the p53 pathway.

Murphy ME.

Cell Death Differ. 2006 Jun;13(6):916-20. Review. No abstract available.


The P53 pathway: what questions remain to be explored?

Levine AJ, Hu W, Feng Z.

Cell Death Differ. 2006 Jun;13(6):1027-36. Review.

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