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Pregenesys pre-eclampsia markers consensus meeting: What do we require from markers, risk assessment and model systems to tailor preventive strategies?

Cetin I, Huppertz B, Burton G, Cuckle H, Gonen R, Lapaire O, Mandia L, Nicolaides K, Redman C, Soothill P, Spencer K, Thilaganathan B, Williams D, Meiri H.

Placenta. 2011 Feb;32 Suppl:S4-16. doi: 10.1016/j.placenta.2010.11.022.


Novel research horizons for presenilins and γ-secretases in cell biology and disease.

De Strooper B, Annaert W.

Annu Rev Cell Dev Biol. 2010;26:235-60. doi: 10.1146/annurev-cellbio-100109-104117. Review.


Proteases and sFlt-1 release in the human placenta.

Zhao S, Gu Y, Fan R, Groome LJ, Cooper D, Wang Y.

Placenta. 2010 Jun;31(6):512-8. doi: 10.1016/j.placenta.2010.03.014.


The ADAM metalloproteinases.

Edwards DR, Handsley MM, Pennington CJ.

Mol Aspects Med. 2008 Oct;29(5):258-89. doi: 10.1016/j.mam.2008.08.001. Review.


Chicken protocadherin-1 functions to localize neural crest cells to the dorsal root ganglia during PNS formation.

Bononi J, Cole A, Tewson P, Schumacher A, Bradley R.

Mech Dev. 2008 Nov-Dec;125(11-12):1033-47. doi: 10.1016/j.mod.2008.07.007.


Contact-dependent promotion of cell migration by the OL-protocadherin-Nap1 interaction.

Nakao S, Platek A, Hirano S, Takeichi M.

J Cell Biol. 2008 Jul 28;182(2):395-410. doi: 10.1083/jcb.200802069.


Identifying autism loci and genes by tracing recent shared ancestry.

Morrow EM, Yoo SY, Flavell SW, Kim TK, Lin Y, Hill RS, Mukaddes NM, Balkhy S, Gascon G, Hashmi A, Al-Saad S, Ware J, Joseph RM, Greenblatt R, Gleason D, Ertelt JA, Apse KA, Bodell A, Partlow JN, Barry B, Yao H, Markianos K, Ferland RJ, Greenberg ME, Walsh CA.

Science. 2008 Jul 11;321(5886):218-23. doi: 10.1126/science.1157657. Erratum in: Science. 2010 Dec 24;330(6012):1746.


Inhibition of protocadherin-alpha function results in neuronal death in the developing zebrafish.

Emond MR, Jontes JD.

Dev Biol. 2008 Sep 1;321(1):175-87. doi: 10.1016/j.ydbio.2008.06.011.


Protocadherin 12 deficiency alters morphogenesis and transcriptional profile of the placenta.

Rampon C, Bouillot S, Climescu-Haulica A, Prandini MH, Cand F, Vandenbrouck Y, Huber P.

Physiol Genomics. 2008 Jul 15;34(2):193-204. doi: 10.1152/physiolgenomics.00220.2007.


X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment.

Dibbens LM, Tarpey PS, Hynes K, Bayly MA, Scheffer IE, Smith R, Bomar J, Sutton E, Vandeleur L, Shoubridge C, Edkins S, Turner SJ, Stevens C, O'Meara S, Tofts C, Barthorpe S, Buck G, Cole J, Halliday K, Jones D, Lee R, Madison M, Mironenko T, Varian J, West S, Widaa S, Wray P, Teague J, Dicks E, Butler A, Menzies A, Jenkinson A, Shepherd R, Gusella JF, Afawi Z, Mazarib A, Neufeld MY, Kivity S, Lev D, Lerman-Sagie T, Korczyn AD, Derry CP, Sutherland GR, Friend K, Shaw M, Corbett M, Kim HG, Geschwind DH, Thomas P, Haan E, Ryan S, McKee S, Berkovic SF, Futreal PA, Stratton MR, Mulley JC, Gécz J.

Nat Genet. 2008 Jun;40(6):776-81. doi: 10.1038/ng.149.


Protocadherin-18a has a role in cell adhesion, behavior and migration in zebrafish development.

Aamar E, Dawid IB.

Dev Biol. 2008 Jun 15;318(2):335-46. doi: 10.1016/j.ydbio.2008.03.040.


ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin.

Schulz B, Pruessmeyer J, Maretzky T, Ludwig A, Blobel CP, Saftig P, Reiss K.

Circ Res. 2008 May 23;102(10):1192-201. doi: 10.1161/CIRCRESAHA.107.169805.


PCDH8, the human homolog of PAPC, is a candidate tumor suppressor of breast cancer.

Yu JS, Koujak S, Nagase S, Li CM, Su T, Wang X, Keniry M, Memeo L, Rojtman A, Mansukhani M, Hibshoosh H, Tycko B, Parsons R.

Oncogene. 2008 Aug 7;27(34):4657-65. doi: 10.1038/onc.2008.101.


Protocadherin family: diversity, structure, and function.

Morishita H, Yagi T.

Curr Opin Cell Biol. 2007 Oct;19(5):584-92. Review.


Prostaglandin E2-EP4 receptor promotes endothelial cell migration via ERK activation and angiogenesis in vivo.

Rao R, Redha R, Macias-Perez I, Su Y, Hao C, Zent R, Breyer MD, Pozzi A.

J Biol Chem. 2007 Jun 8;282(23):16959-68.


Src kinase phosphorylates vascular endothelial-cadherin in response to vascular endothelial growth factor: identification of tyrosine 685 as the unique target site.

Wallez Y, Cand F, Cruzalegui F, Wernstedt C, Souchelnytskyi S, Vilgrain I, Huber P.

Oncogene. 2007 Feb 15;26(7):1067-77.


Soluble endoglin contributes to the pathogenesis of preeclampsia.

Venkatesha S, Toporsian M, Lam C, Hanai J, Mammoto T, Kim YM, Bdolah Y, Lim KH, Yuan HT, Libermann TA, Stillman IE, Roberts D, D'Amore PA, Epstein FH, Sellke FW, Romero R, Sukhatme VP, Letarte M, Karumanchi SA.

Nat Med. 2006 Jun;12(6):642-9. Erratum in: Nat Med. 2006 Jul;12(7):862.


Regulated ADAM10-dependent ectodomain shedding of gamma-protocadherin C3 modulates cell-cell adhesion.

Reiss K, Maretzky T, Haas IG, Schulte M, Ludwig A, Frank M, Saftig P.

J Biol Chem. 2006 Aug 4;281(31):21735-44.


Signaling mechanisms regulating endothelial permeability.

Mehta D, Malik AB.

Physiol Rev. 2006 Jan;86(1):279-367. Review.


Tracing the glycogen cells with protocadherin 12 during mouse placenta development.

Bouillot S, Rampon C, Tillet E, Huber P.

Placenta. 2006 Aug;27(8):882-8.

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