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The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome.

Song EJ, Werner SL, Neubauer J, Stegmeier F, Aspden J, Rio D, Harper JW, Elledge SJ, Kirschner MW, Rape M.

Genes Dev. 2010 Jul 1;24(13):1434-47. doi: 10.1101/gad.1925010.


The Prp19 WD40 domain contains a conserved protein interaction region essential for its function.

Vander Kooi CW, Ren L, Xu P, Ohi MD, Gould KL, Chazin WJ.

Structure. 2010 May 12;18(5):584-93. doi: 10.1016/j.str.2010.02.015.


Molecular architecture of the human Prp19/CDC5L complex.

Grote M, Wolf E, Will CL, Lemm I, Agafonov DE, Schomburg A, Fischle W, Urlaub H, Lührmann R.

Mol Cell Biol. 2010 May;30(9):2105-19. doi: 10.1128/MCB.01505-09. Epub 2010 Feb 22.


Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing.

Lardelli RM, Thompson JX, Yates JR 3rd, Stevens SW.

RNA. 2010 Mar;16(3):516-28. doi: 10.1261/rna.2030510. Epub 2010 Jan 20.


The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome.

Fabrizio P, Dannenberg J, Dube P, Kastner B, Stark H, Urlaub H, Lührmann R.

Mol Cell. 2009 Nov 25;36(4):593-608. doi: 10.1016/j.molcel.2009.09.040.


Nonsense-mediated mRNA decay mutes the splicing defects of spliceosome component mutations.

Kawashima T, Pellegrini M, Chanfreau GF.

RNA. 2009 Dec;15(12):2236-47. doi: 10.1261/rna.1736809. Epub 2009 Oct 22.


IDPicker 2.0: Improved protein assembly with high discrimination peptide identification filtering.

Ma ZQ, Dasari S, Chambers MC, Litton MD, Sobecki SM, Zimmerman LJ, Halvey PJ, Schilling B, Drake PM, Gibson BW, Tabb DL.

J Proteome Res. 2009 Aug;8(8):3872-81. doi: 10.1021/pr900360j.


The SH3 domains of two PCH family members cooperate in assembly of the Schizosaccharomyces pombe contractile ring.

Roberts-Galbraith RH, Chen JS, Wang J, Gould KL.

J Cell Biol. 2009 Jan 12;184(1):113-27. doi: 10.1083/jcb.200806044.


A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing.

Wilmes GM, Bergkessel M, Bandyopadhyay S, Shales M, Braberg H, Cagney G, Collins SR, Whitworth GB, Kress TL, Weissman JS, Ideker T, Guthrie C, Krogan NJ.

Mol Cell. 2008 Dec 5;32(5):735-46. doi: 10.1016/j.molcel.2008.11.012.


Splicing factors facilitate RNAi-directed silencing in fission yeast.

Bayne EH, Portoso M, Kagansky A, Kos-Braun IC, Urano T, Ekwall K, Alves F, Rappsilber J, Allshire RC.

Science. 2008 Oct 24;322(5901):602-6. doi: 10.1126/science.1164029.


The exosome: a multipurpose RNA-decay machine.

Schmid M, Jensen TH.

Trends Biochem Sci. 2008 Oct;33(10):501-10. doi: 10.1016/j.tibs.2008.07.003. Epub 2008 Sep 9. Review.


Drosophila MFAP1 is required for pre-mRNA processing and G2/M progression.

Andersen DS, Tapon N.

J Biol Chem. 2008 Nov 7;283(45):31256-67. doi: 10.1074/jbc.M803512200. Epub 2008 Sep 2.


Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1.

Conticello SG, Ganesh K, Xue K, Lu M, Rada C, Neuberger MS.

Mol Cell. 2008 Aug 22;31(4):474-84. doi: 10.1016/j.molcel.2008.07.009.


High-quality binary protein interaction map of the yeast interactome network.

Yu H, Braun P, Yildirim MA, Lemmens I, Venkatesan K, Sahalie J, Hirozane-Kishikawa T, Gebreab F, Li N, Simonis N, Hao T, Rual JF, Dricot A, Vazquez A, Murray RR, Simon C, Tardivo L, Tam S, Svrzikapa N, Fan C, de Smet AS, Motyl A, Hudson ME, Park J, Xin X, Cusick ME, Moore T, Boone C, Snyder M, Roth FP, Barabási AL, Tavernier J, Hill DE, Vidal M.

Science. 2008 Oct 3;322(5898):104-10. doi: 10.1126/science.1158684. Epub 2008 Aug 21.


The splicing factor Prp17 interacts with the U2, U5 and U6 snRNPs and associates with the spliceosome pre- and post-catalysis.

Sapra AK, Khandelia P, Vijayraghavan U.

Biochem J. 2008 Dec 15;416(3):365-74. doi: 10.1042/BJ20081195.


Linking functionally related genes by sensitive and quantitative characterization of genetic interaction profiles.

Decourty L, Saveanu C, Zemam K, Hantraye F, Frachon E, Rousselle JC, Fromont-Racine M, Jacquier A.

Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5821-6. doi: 10.1073/pnas.0710533105. Epub 2008 Apr 11.


Proteomic parsimony through bipartite graph analysis improves accuracy and transparency.

Zhang B, Chambers MC, Tabb DL.

J Proteome Res. 2007 Sep;6(9):3549-57. Epub 2007 Aug 4.


Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors.

Chen YI, Moore RE, Ge HY, Young MK, Lee TD, Stevens SW.

Nucleic Acids Res. 2007;35(12):3928-44. Epub 2007 May 30.


Structural characterization of the fission yeast U5.U2/U6 spliceosome complex.

Ohi MD, Ren L, Wall JS, Gould KL, Walz T.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3195-200. Epub 2007 Feb 20.

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