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Items: 1 to 20 of 61

1.

Overexpression of Fto leads to increased food intake and results in obesity.

Church C, Moir L, McMurray F, Girard C, Banks GT, Teboul L, Wells S, Brüning JC, Nolan PM, Ashcroft FM, Cox RD.

Nat Genet. 2010 Dec;42(12):1086-92. doi: 10.1038/ng.713. Epub 2010 Nov 14.

2.

SITAR--a useful instrument for growth curve analysis.

Cole TJ, Donaldson MD, Ben-Shlomo Y.

Int J Epidemiol. 2010 Dec;39(6):1558-66. doi: 10.1093/ije/dyq115. Epub 2010 Jul 20.

3.

Relation of immediate postnatal growth with obesity and related metabolic risk factors in adulthood: the northern Finland birth cohort 1966 study.

Tzoulaki I, Sovio U, Pillas D, Hartikainen AL, Pouta A, Laitinen J, Tammelin TH, Jarvelin MR, Elliott P.

Am J Epidemiol. 2010 May 1;171(9):989-98. doi: 10.1093/aje/kwq027. Epub 2010 Apr 1.

PMID:
20360243
4.

Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats.

Tung YC, Ayuso E, Shan X, Bosch F, O'Rahilly S, Coll AP, Yeo GS.

PLoS One. 2010 Jan 19;5(1):e8771. doi: 10.1371/journal.pone.0008771.

5.

Life course variations in the associations between FTO and MC4R gene variants and body size.

Hardy R, Wills AK, Wong A, Elks CE, Wareham NJ, Loos RJ, Kuh D, Ong KK.

Hum Mol Genet. 2010 Feb 1;19(3):545-52. doi: 10.1093/hmg/ddp504. Epub 2009 Oct 31.

6.

Hypothalamic FTO is associated with the regulation of energy intake not feeding reward.

Olszewski PK, Fredriksson R, Olszewska AM, Stephansson O, Alsiö J, Radomska KJ, Levine AS, Schiöth HB.

BMC Neurosci. 2009 Oct 27;10:129. doi: 10.1186/1471-2202-10-129.

7.

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.

Church C, Lee S, Bagg EA, McTaggart JS, Deacon R, Gerken T, Lee A, Moir L, Mecinović J, Quwailid MM, Schofield CJ, Ashcroft FM, Cox RD.

PLoS Genet. 2009 Aug;5(8):e1000599. doi: 10.1371/journal.pgen.1000599. Epub 2009 Aug 14.

8.

Genetic and environmental effects on body mass index during adolescence: a prospective study among Finnish twins.

Lajunen HR, Kaprio J, Keski-Rahkonen A, Rose RJ, Pulkkinen L, Rissanen A, Silventoinen K.

Int J Obes (Lond). 2009 May;33(5):559-67. doi: 10.1038/ijo.2009.51. Epub 2009 Mar 31.

9.

Inactivation of the Fto gene protects from obesity.

Fischer J, Koch L, Emmerling C, Vierkotten J, Peters T, Brüning JC, Rüther U.

Nature. 2009 Apr 16;458(7240):894-8. doi: 10.1038/nature07848. Epub 2009 Feb 22.

PMID:
19234441
10.

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstråle M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Stephens J, Stevens S, Stringham HM, Tung YC, Valle TT, Van Duijn CM, Vimaleswaran KS, Vollenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N; Wellcome Trust Case Control Consortium, Witteman JC, Zeggini E, Zhai G, Zillikens MC, Altshuler D, Caulfield MJ, Chanock SJ, Farooqi IS, Ferrucci L, Guralnik JM, Hattersley AT, Hu FB, Jarvelin MR, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Mohlke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann HE, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, Hirschhorn JN; Genetic Investigation of ANthropometric Traits Consortium.

Nat Genet. 2009 Jan;41(1):25-34. doi: 10.1038/ng.287. Epub 2008 Dec 14.

11.

An obesity-associated FTO gene variant and increased energy intake in children.

Cecil JE, Tavendale R, Watt P, Hetherington MM, Palmer CN.

N Engl J Med. 2008 Dec 11;359(24):2558-66. doi: 10.1056/NEJMoa0803839.

12.

Patterns of growth associated with the timing of adiposity rebound.

Williams SM, Goulding A.

Obesity (Silver Spring). 2009 Feb;17(2):335-41. doi: 10.1038/oby.2008.547. Epub 2008 Dec 4.

13.

The FTO obesity gene. Genotyping and gene expression analysis in morbidly obese patients.

Zabena C, González-Sánchez JL, Martínez-Larrad MT, Torres-García A, Alvarez-Fernández-Represa J, Corbatón-Anchuelo A, Pérez-Barba M, Serrano-Ríos M.

Obes Surg. 2009 Jan;19(1):87-95. doi: 10.1007/s11695-008-9727-0. Epub 2008 Oct 15.

PMID:
18855084
14.

Increasing heritability of BMI and stronger associations with the FTO gene over childhood.

Haworth CM, Carnell S, Meaburn EL, Davis OS, Plomin R, Wardle J.

Obesity (Silver Spring). 2008 Dec;16(12):2663-8. doi: 10.1038/oby.2008.434. Epub 2008 Oct 9.

15.

The fat mass- and obesity-associated locus and dietary intake in children.

Timpson NJ, Emmett PM, Frayling TM, Rogers I, Hattersley AT, McCarthy MI, Davey Smith G.

Am J Clin Nutr. 2008 Oct;88(4):971-8.

16.

The FTO gene and measured food intake in children.

Wardle J, Llewellyn C, Sanderson S, Plomin R.

Int J Obes (Lond). 2009 Jan;33(1):42-5. doi: 10.1038/ijo.2008.174. Epub 2008 Oct 7.

PMID:
18838977
17.

The FTO gene is associated with adulthood obesity in the Mexican population.

Villalobos-Comparán M, Teresa Flores-Dorantes M, Teresa Villarreal-Molina M, Rodríguez-Cruz M, García-Ulloa AC, Robles L, Huertas-Vázquez A, Saucedo-Villarreal N, López-Alarcón M, Sánchez-Muñoz F, Domínguez-López A, Gutiérrez-Aguilar R, Menjivar M, Coral-Vázquez R, Hernández-Stengele G, Vital-Reyes VS, Acuña-Alonzo V, Romero-Hidalgo S, Ruiz-Gómez DG, Riaño-Barros D, Herrera MF, Gómez-Pérez FJ, Froguel P, García-García E, Teresa Tusié-Luna M, Aguilar-Salinas CA, Canizales-Quinteros S.

Obesity (Silver Spring). 2008 Oct;16(10):2296-301. doi: 10.1038/oby.2008.367. Epub 2008 Jul 31.

18.

Impact on weight dynamics and general growth of the common FTO rs9939609: a longitudinal Danish cohort study.

Jess T, Zimmermann E, Kring SI, Berentzen T, Holst C, Toubro S, Astrup A, Hansen T, Pedersen O, Sørensen TI.

Int J Obes (Lond). 2008 Sep;32(9):1388-94. doi: 10.1038/ijo.2008.110. Epub 2008 Jul 29.

PMID:
18663371
19.

Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test.

Qi L, Kang K, Zhang C, van Dam RM, Kraft P, Hunter D, Lee CH, Hu FB.

Diabetes. 2008 Nov;57(11):3145-51. doi: 10.2337/db08-0006. Epub 2008 Jul 22.

20.

Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure.

Speakman JR, Rance KA, Johnstone AM.

Obesity (Silver Spring). 2008 Aug;16(8):1961-5. doi: 10.1038/oby.2008.318. Epub 2008 Jun 12.

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