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A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells.

Marchetto MC, Carromeu C, Acab A, Yu D, Yeo GW, Mu Y, Chen G, Gage FH, Muotri AR.

Cell. 2010 Nov 12;143(4):527-39. doi: 10.1016/j.cell.2010.10.016.


The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation.

Tian D, Sun S, Lee JT.

Cell. 2010 Oct 29;143(3):390-403. doi: 10.1016/j.cell.2010.09.049.


Induced pluripotency: history, mechanisms, and applications.

Stadtfeld M, Hochedlinger K.

Genes Dev. 2010 Oct 15;24(20):2239-63. doi: 10.1101/gad.1963910. Review.


Female human iPSCs retain an inactive X chromosome.

Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle AD, Lowry WE, Plath K.

Cell Stem Cell. 2010 Sep 3;7(3):329-42. doi: 10.1016/j.stem.2010.06.024. Epub 2010 Aug 19.


Variations of X chromosome inactivation occur in early passages of female human embryonic stem cells.

Dvash T, Lavon N, Fan G.

PLoS One. 2010 Jun 25;5(6):e11330. doi: 10.1371/journal.pone.0011330.


An embryonic story: analysis of the gene regulative network controlling Xist expression in mouse embryonic stem cells.

Navarro P, Avner P.

Bioessays. 2010 Jul;32(7):581-8. doi: 10.1002/bies.201000019. Review. Erratum in: Bioessays. 2010 Jul;32(7):641.


Nuclear reprogramming to a pluripotent state by three approaches.

Yamanaka S, Blau HM.

Nature. 2010 Jun 10;465(7299):704-12. doi: 10.1038/nature09229. Review.


Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

Lengner CJ, Gimelbrant AA, Erwin JA, Cheng AW, Guenther MG, Welstead GG, Alagappan R, Frampton GM, Xu P, Muffat J, Santagata S, Powers D, Barrett CB, Young RA, Lee JT, Jaenisch R, Mitalipova M.

Cell. 2010 May 28;141(5):872-83. doi: 10.1016/j.cell.2010.04.010. Epub 2010 May 13.


Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs.

Hanna J, Cheng AW, Saha K, Kim J, Lengner CJ, Soldner F, Cassady JP, Muffat J, Carey BW, Jaenisch R.

Proc Natl Acad Sci U S A. 2010 May 18;107(20):9222-7. doi: 10.1073/pnas.1004584107. Epub 2010 May 4.


Two-step imprinted X inactivation: repeat versus genic silencing in the mouse.

Namekawa SH, Payer B, Huynh KD, Jaenisch R, Lee JT.

Mol Cell Biol. 2010 Jul;30(13):3187-205. doi: 10.1128/MCB.00227-10. Epub 2010 Apr 19.


Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome.

Lee JT.

Genes Dev. 2009 Aug 15;23(16):1831-42. doi: 10.1101/gad.1811209.


Elite and stochastic models for induced pluripotent stem cell generation.

Yamanaka S.

Nature. 2009 Jul 2;460(7251):49-52. doi: 10.1038/nature08180.


Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures.

Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C, Ambartsumyan G, Aimiuwu O, Richter L, Zhang J, Khvorostov I, Ott V, Grunstein M, Lavon N, Benvenisty N, Croce CM, Clark AT, Baxter T, Pyle AD, Teitell MA, Pelegrini M, Plath K, Lowry WE.

Cell Stem Cell. 2009 Jul 2;5(1):111-23. doi: 10.1016/j.stem.2009.06.008.


The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting.

Donohoe ME, Silva SS, Pinter SF, Xu N, Lee JT.

Nature. 2009 Jul 2;460(7251):128-32. doi: 10.1038/nature08098. Epub 2009 Jun 17.


Naive and primed pluripotent states.

Nichols J, Smith A.

Cell Stem Cell. 2009 Jun 5;4(6):487-92. doi: 10.1016/j.stem.2009.05.015. Review.


A fresh look at iPS cells.

Yamanaka S.

Cell. 2009 Apr 3;137(1):13-7. doi: 10.1016/j.cell.2009.03.034.


Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells.

Ware CB, Wang L, Mecham BH, Shen L, Nelson AM, Bar M, Lamba DA, Dauphin DS, Buckingham B, Askari B, Lim R, Tewari M, Gartler SM, Issa JP, Pavlidis P, Duan Z, Blau CA.

Cell Stem Cell. 2009 Apr 3;4(4):359-69. doi: 10.1016/j.stem.2009.03.001.


Klf4 reverts developmentally programmed restriction of ground state pluripotency.

Guo G, Yang J, Nichols J, Hall JS, Eyres I, Mansfield W, Smith A.

Development. 2009 Apr;136(7):1063-9. doi: 10.1242/dev.030957. Epub 2009 Feb 18.


X chromosome inactivation in the absence of Dicer.

Kanellopoulou C, Muljo SA, Dimitrov SD, Chen X, Colin C, Plath K, Livingston DM.

Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1122-7. doi: 10.1073/pnas.0812210106. Epub 2009 Jan 21.

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