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Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans.

Bielesz B, Sirin Y, Si H, Niranjan T, Gruenwald A, Ahn S, Kato H, Pullman J, Gessler M, Haase VH, Susztak K.

J Clin Invest. 2010 Nov;120(11):4040-54. doi: 10.1172/JCI43025.


Mechanisms of tubulointerstitial fibrosis.

Zeisberg M, Neilson EG.

J Am Soc Nephrol. 2010 Nov;21(11):1819-34. doi: 10.1681/ASN.2010080793. Review.


Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells.

Koesters R, Kaissling B, Lehir M, Picard N, Theilig F, Gebhardt R, Glick AB, Hähnel B, Hosser H, Gröne HJ, Kriz W.

Am J Pathol. 2010 Aug;177(2):632-43. doi: 10.2353/ajpath.2010.091012.


The epithelial-to-mesenchymal transition in liver fibrosis: here today, gone tomorrow?

Wells RG.

Hepatology. 2010 Mar;51(3):737-40. doi: 10.1002/hep.23529. No abstract available.


Autophagy is a component of epithelial cell fate in obstructive uropathy.

Li L, Zepeda-Orozco D, Black R, Lin F.

Am J Pathol. 2010 Apr;176(4):1767-78. doi: 10.2353/ajpath.2010.090345.


Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice.

Taura K, Miura K, Iwaisako K, Osterreicher CH, Kodama Y, Penz-Osterreicher M, Brenner DA.

Hepatology. 2010 Mar;51(3):1027-36. doi: 10.1002/hep.23368.


S100A4 and metastasis: a small actor playing many roles.

Boye K, Maelandsmo GM.

Am J Pathol. 2010 Feb;176(2):528-35. doi: 10.2353/ajpath.2010.090526. Review.


The origin of renal fibroblasts and progression of kidney disease.

Cook HT.

Am J Pathol. 2010 Jan;176(1):22-4. doi: 10.2353/ajpath.2010.090898. No abstract available.


Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis.

Humphreys BD, Lin SL, Kobayashi A, Hudson TE, Nowlin BT, Bonventre JV, Valerius MT, McMahon AP, Duffield JS.

Am J Pathol. 2010 Jan;176(1):85-97. doi: 10.2353/ajpath.2010.090517.


Epithelial-mesenchymal transitions in development and disease.

Thiery JP, Acloque H, Huang RY, Nieto MA.

Cell. 2009 Nov 25;139(5):871-90. doi: 10.1016/j.cell.2009.11.007. Review.


Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease.

Hakroush S, Moeller MJ, Theilig F, Kaissling B, Sijmonsma TP, Jugold M, Akeson AL, Traykova-Brauch M, Hosser H, Hähnel B, Gröne HJ, Koesters R, Kriz W.

Am J Pathol. 2009 Nov;175(5):1883-95. doi: 10.2353/ajpath.2009.080792.


Biomarkers for epithelial-mesenchymal transitions.

Zeisberg M, Neilson EG.

J Clin Invest. 2009 Jun;119(6):1429-37. doi: 10.1172/JCI36183. Review.


The basics of epithelial-mesenchymal transition.

Kalluri R, Weinberg RA.

J Clin Invest. 2009 Jun;119(6):1420-8. doi: 10.1172/JCI39104. Review. Erratum in: J Clin Invest. 2010 May 3;120(5):1786.


Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney.

Lin SL, Kisseleva T, Brenner DA, Duffield JS.

Am J Pathol. 2008 Dec;173(6):1617-27. doi: 10.2353/ajpath.2008.080433.


Dog as model for down-expression of E-cadherin and beta-catenin in tubular epithelial cells in renal fibrosis.

Aresu L, Rastaldi MP, Pregel P, Valenza F, Radaelli E, Scanziani E, Castagnaro M.

Virchows Arch. 2008 Dec;453(6):617-25. doi: 10.1007/s00428-008-0684-8.


An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.

Traykova-Brauch M, Schönig K, Greiner O, Miloud T, Jauch A, Bode M, Felsher DW, Glick AB, Kwiatkowski DJ, Bujard H, Horst J, von Knebel Doeberitz M, Niggli FK, Kriz W, Gröne HJ, Koesters R.

Nat Med. 2008 Sep;14(9):979-84. doi: 10.1038/nm.1865.


The renal cortical interstitium: morphological and functional aspects.

Kaissling B, Le Hir M.

Histochem Cell Biol. 2008 Aug;130(2):247-62. doi: 10.1007/s00418-008-0452-5. Review.


Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat.

Picard N, Baum O, Vogetseder A, Kaissling B, Le Hir M.

Histochem Cell Biol. 2008 Jul;130(1):141-55. doi: 10.1007/s00418-008-0433-8.


Mesenchymal transition in kidney collecting duct epithelial cells.

Ivanova L, Butt MJ, Matsell DG.

Am J Physiol Renal Physiol. 2008 May;294(5):F1238-48. doi: 10.1152/ajprenal.00326.2007.


The role of tubular epithelial-mesenchymal transition in progressive kidney disease.

Burns WC, Kantharidis P, Thomas MC.

Cells Tissues Organs. 2007;185(1-3):222-31. Review.

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