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Items: 1 to 20 of 50

1.

Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodents.

Georgia S, Hinault C, Kawamori D, Hu J, Meyer J, Kanji M, Bhushan A, Kulkarni RN.

Diabetes. 2010 Apr;59(4):987-96. doi: 10.2337/db09-0838. Epub 2010 Jan 26.

2.

Regenerating pancreatic beta-cells: plasticity of adult pancreatic cells and the feasibility of in-vivo neogenesis.

Juhl K, Bonner-Weir S, Sharma A.

Curr Opin Organ Transplant. 2010 Feb;15(1):79-85. doi: 10.1097/MOT.0b013e3283344932. Review.

3.

Absence of p53-dependent apoptosis combined with nonhomologous end-joining deficiency leads to a severe diabetic phenotype in mice.

Tavana O, Puebla-Osorio N, Sang M, Zhu C.

Diabetes. 2010 Jan;59(1):135-42. doi: 10.2337/db09-0792. Epub 2009 Oct 15.

4.

An Osteoblast-dependent mechanism contributes to the leptin regulation of insulin secretion.

Hinoi E, Gao N, Jung DY, Yadav V, Yoshizawa T, Kajimura D, Myers MG Jr, Chua SC Jr, Wang Q, Kim JK, Kaestner KH, Karsenty G.

Ann N Y Acad Sci. 2009 Sep;1173 Suppl 1:E20-30. doi: 10.1111/j.1749-6632.2009.05061.x. Erratum in: Ann N Y Acad Sci. 2011 Oct;1234(1):174.

5.

A crucial role for adipose tissue p53 in the regulation of insulin resistance.

Minamino T, Orimo M, Shimizu I, Kunieda T, Yokoyama M, Ito T, Nojima A, Nabetani A, Oike Y, Matsubara H, Ishikawa F, Komuro I.

Nat Med. 2009 Sep;15(9):1082-7. doi: 10.1038/nm.2014. Epub 2009 Aug 30.

PMID:
19718037
6.

Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus.

Chen H, Gu X, Su IH, Bottino R, Contreras JL, Tarakhovsky A, Kim SK.

Genes Dev. 2009 Apr 15;23(8):975-85. doi: 10.1101/gad.1742509.

7.

Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo.

Fiaschi-Taesch N, Bigatel TA, Sicari B, Takane KK, Salim F, Velazquez-Garcia S, Harb G, Selk K, Cozar-Castellano I, Stewart AF.

Diabetes. 2009 Apr;58(4):882-93. doi: 10.2337/db08-0631. Epub 2009 Jan 9.

8.

Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth.

Inada A, Nienaber C, Katsuta H, Fujitani Y, Levine J, Morita R, Sharma A, Bonner-Weir S.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19915-9. doi: 10.1073/pnas.0805803105. Epub 2008 Dec 3.

9.

Differential expression of cell cycle proteins during ageing of pancreatic islet cells.

Hinault C, Hu J, Maier BF, Mirmira RG, Kulkarni RN.

Diabetes Obes Metab. 2008 Nov;10 Suppl 4:136-46. doi: 10.1111/j.1463-1326.2008.00947.x. Review.

PMID:
18834441
10.

Growth factor control of pancreatic islet regeneration and function.

Assmann A, Hinault C, Kulkarni RN.

Pediatr Diabetes. 2009 Feb;10(1):14-32. doi: 10.1111/j.1399-5448.2008.00468.x. Epub 2008 Sep 19. Review. No abstract available.

11.

The tumour-suppressor p53 is not required for pancreatic beta cell death during diabetes and upon irradiation.

Nam SY, Lee MK, Sabapathy K.

J Physiol. 2008 Jan 15;586(2):407-17. Epub 2007 Nov 15.

12.

Regenerative capacity of neural precursors in the adult mammalian brain is under the control of p53.

Medrano S, Burns-Cusato M, Atienza MB, Rahimi D, Scrable H.

Neurobiol Aging. 2009 Mar;30(3):483-97. Epub 2007 Sep 11.

13.

p53 and its isoforms in cancer.

Bourdon JC.

Br J Cancer. 2007 Aug 6;97(3):277-82. Epub 2007 Jul 17. Review.

14.

Growth and regeneration of adult beta cells does not involve specialized progenitors.

Teta M, Rankin MM, Long SY, Stein GM, Kushner JA.

Dev Cell. 2007 May;12(5):817-26.

15.

The emerging role of FOXO transcription factors in pancreatic beta cells.

Glauser DA, Schlegel W.

J Endocrinol. 2007 May;193(2):195-207. Review.

16.

Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance.

Okada T, Liew CW, Hu J, Hinault C, Michael MD, Krtzfeldt J, Yin C, Holzenberger M, Stoffel M, Kulkarni RN.

Proc Natl Acad Sci U S A. 2007 May 22;104(21):8977-82. Epub 2007 Apr 6.

17.

Increased islet beta cell replication adjacent to intrapancreatic gastrinomas in humans.

Meier JJ, Butler AE, Galasso R, Rizza RA, Butler PC.

Diabetologia. 2006 Nov;49(11):2689-96. Epub 2006 Sep 23.

PMID:
17016695
18.

Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression.

Spurgers KB, Gold DL, Coombes KR, Bohnenstiehl NL, Mullins B, Meyn RE, Logothetis CJ, McDonnell TJ.

J Biol Chem. 2006 Sep 1;281(35):25134-42. Epub 2006 Jun 23.

19.

Molecular control of cell cycle progression in the pancreatic beta-cell.

Cozar-Castellano I, Fiaschi-Taesch N, Bigatel TA, Takane KK, Garcia-OcaƱa A, Vasavada R, Stewart AF.

Endocr Rev. 2006 Jun;27(4):356-70. Epub 2006 Apr 25. Review.

PMID:
16638909
20.

Relationship between beta-cell mass and fasting blood glucose concentration in humans.

Ritzel RA, Butler AE, Rizza RA, Veldhuis JD, Butler PC.

Diabetes Care. 2006 Mar;29(3):717-8. No abstract available.

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