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Items: 1 to 20 of 47

1.

Cannabinoid receptors are coupled to stimulation of insulin secretion from mouse MIN6 beta-cells.

Li C, Jones PM, Persaud SJ.

Cell Physiol Biochem. 2010;26(2):187-96. doi: 10.1159/000320527. Epub 2010 Aug 24.

2.

Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity.

Tam J, Vemuri VK, Liu J, Bátkai S, Mukhopadhyay B, Godlewski G, Osei-Hyiaman D, Ohnuma S, Ambudkar SV, Pickel J, Makriyannis A, Kunos G.

J Clin Invest. 2010 Aug;120(8):2953-66. doi: 10.1172/JCI42551. Epub 2010 Jul 26. Erratum in: J Clin Invest. 2010 Oct 1;120(10):3735.

3.

Serotonin regulates pancreatic beta cell mass during pregnancy.

Kim H, Toyofuku Y, Lynn FC, Chak E, Uchida T, Mizukami H, Fujitani Y, Kawamori R, Miyatsuka T, Kosaka Y, Yang K, Honig G, van der Hart M, Kishimoto N, Wang J, Yagihashi S, Tecott LH, Watada H, German MS.

Nat Med. 2010 Jul;16(7):804-8. doi: 10.1038/nm.2173. Epub 2010 Jun 27.

4.

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7.

Rajagopal S, Kim J, Ahn S, Craig S, Lam CM, Gerard NP, Gerard C, Lefkowitz RJ.

Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):628-32. doi: 10.1073/pnas.0912852107. Epub 2009 Dec 17.

5.

Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells.

Lipina C, Stretton C, Hastings S, Hundal JS, Mackie K, Irving AJ, Hundal HS.

Diabetes. 2010 Feb;59(2):375-85. doi: 10.2337/db09-0979. Epub 2009 Nov 23.

6.

The CB1 antagonist rimonabant decreases insulin hypersecretion in rat pancreatic islets.

Getty-Kaushik L, Richard AM, Deeney JT, Krawczyk S, Shirihai O, Corkey BE.

Obesity (Silver Spring). 2009 Oct;17(10):1856-60. doi: 10.1038/oby.2009.234. Epub 2009 Jul 30.

7.

The endocannabinoid system: role in glucose and energy metabolism.

Nogueiras R, Diaz-Arteaga A, Lockie SH, Velásquez DA, Tschop J, López M, Cadwell CC, Diéguez C, Tschöp MH.

Pharmacol Res. 2009 Aug;60(2):93-8. doi: 10.1016/j.phrs.2009.04.004. Epub 2009 Apr 14. Review.

PMID:
19559361
8.

Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding.

Izzo AA, Piscitelli F, Capasso R, Aviello G, Romano B, Borrelli F, Petrosino S, Di Marzo V.

Br J Pharmacol. 2009 Sep;158(2):451-61. doi: 10.1111/j.1476-5381.2009.00183.x. Epub 2009 Apr 3.

9.

The role of the pancreatic endocannabinoid system in glucose metabolism.

Bermúdez-Silva FJ, Suárez Pérez J, Nadal A, Rodríguez de Fonseca F.

Best Pract Res Clin Endocrinol Metab. 2009 Feb;23(1):87-102. doi: 10.1016/j.beem.2008.10.012. Review.

PMID:
19285263
10.

Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

Assmann A, Ueki K, Winnay JN, Kadowaki T, Kulkarni RN.

Mol Cell Biol. 2009 Jun;29(11):3219-28. doi: 10.1128/MCB.01489-08. Epub 2009 Mar 9.

11.

Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle.

Eckardt K, Sell H, Taube A, Koenen M, Platzbecker B, Cramer A, Horrighs A, Lehtonen M, Tennagels N, Eckel J.

Diabetologia. 2009 Apr;52(4):664-74. doi: 10.1007/s00125-008-1240-4. Epub 2008 Dec 17.

PMID:
19089403
12.

A critical review of the cannabinoid receptor as a drug target for obesity management.

Akbas F, Gasteyger C, Sjödin A, Astrup A, Larsen TM.

Obes Rev. 2009 Jan;10(1):58-67. doi: 10.1111/j.1467-789X.2008.00520.x. Epub 2008 Aug 20. Review.

PMID:
18721231
13.

Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats.

Nogueiras R, Veyrat-Durebex C, Suchanek PM, Klein M, Tschöp J, Caldwell C, Woods SC, Wittmann G, Watanabe M, Liposits Z, Fekete C, Reizes O, Rohner-Jeanrenaud F, Tschöp MH.

Diabetes. 2008 Nov;57(11):2977-91. doi: 10.2337/db08-0161. Epub 2008 Aug 20.

14.

Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice.

Osei-Hyiaman D, Liu J, Zhou L, Godlewski G, Harvey-White J, Jeong WI, Bátkai S, Marsicano G, Lutz B, Buettner C, Kunos G.

J Clin Invest. 2008 Sep;118(9):3160-9. doi: 10.1172/JCI34827.

15.

The cannabinoid CB1 receptor is expressed in pancreatic delta-cells.

Tharp WG, Lee YH, Maple RL, Pratley RE.

Biochem Biophys Res Commun. 2008 Aug 8;372(4):595-600. doi: 10.1016/j.bbrc.2008.05.077. Epub 2008 May 27.

PMID:
18505678
16.

Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet.

Starowicz KM, Cristino L, Matias I, Capasso R, Racioppi A, Izzo AA, Di Marzo V.

Obesity (Silver Spring). 2008 Mar;16(3):553-65. doi: 10.1038/oby.2007.106. Epub 2008 Jan 17.

17.

Antidiabetic effects of sub-chronic administration of the cannabinoid receptor (CB1) antagonist, AM251, in obese diabetic (ob/ob) mice.

Irwin N, Hunter K, Frizzell N, Flatt PR.

Eur J Pharmacol. 2008 Feb 26;581(1-2):226-33. doi: 10.1016/j.ejphar.2007.12.003. Epub 2007 Dec 14.

PMID:
18191122
18.

Presence of functional cannabinoid receptors in human endocrine pancreas.

Bermúdez-Silva FJ, Suárez J, Baixeras E, Cobo N, Bautista D, Cuesta-Muñoz AL, Fuentes E, Juan-Pico P, Castro MJ, Milman G, Mechoulam R, Nadal A, Rodríguez de Fonseca F.

Diabetologia. 2008 Mar;51(3):476-87. Epub 2007 Dec 19.

PMID:
18092149
19.

Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.

Regard JB, Kataoka H, Cano DA, Camerer E, Yin L, Zheng YW, Scanlan TS, Hebrok M, Coughlin SR.

J Clin Invest. 2007 Dec;117(12):4034-43.

20.

Cannabinoids inhibit insulin secretion and cytosolic Ca2+ oscillation in islet beta-cells via CB1 receptors.

Nakata M, Yada T.

Regul Pept. 2008 Jan 10;145(1-3):49-53. Epub 2007 Aug 24.

PMID:
17884194

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