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Items: 1 to 20 of 23

1.

Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure.

van Oort RJ, McCauley MD, Dixit SS, Pereira L, Yang Y, Respress JL, Wang Q, De Almeida AC, Skapura DG, Anderson ME, Bers DM, Wehrens XH.

Circulation. 2010 Dec 21;122(25):2669-79. doi: 10.1161/CIRCULATIONAHA.110.982298. Epub 2010 Nov 15.

2.

T-tubule remodeling during transition from hypertrophy to heart failure.

Wei S, Guo A, Chen B, Kutschke W, Xie YP, Zimmerman K, Weiss RM, Anderson ME, Cheng H, Song LS.

Circ Res. 2010 Aug 20;107(4):520-31. doi: 10.1161/CIRCRESAHA.109.212324. Epub 2010 Jun 24.

3.

Two-photon laser scanning microscopy of the transverse-axial tubule system in ventricular cardiomyocytes from failing and non-failing human hearts.

Ohler A, Weisser-Thomas J, Piacentino V, Houser SR, Tomaselli GF, O'Rourke B.

Cardiol Res Pract. 2009;2009:802373. doi: 10.4061/2009/802373. Epub 2010 Mar 7.

4.

Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model.

van Oort RJ, Respress JL, Li N, Reynolds C, De Almeida AC, Skapura DG, De Windt LJ, Wehrens XH.

Hypertension. 2010 Apr;55(4):932-8. doi: 10.1161/HYPERTENSIONAHA.109.146449. Epub 2010 Feb 15.

5.

Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.

Chopra N, Yang T, Asghari P, Moore ED, Huke S, Akin B, Cattolica RA, Perez CF, Hlaing T, Knollmann-Ritschel BE, Jones LR, Pessah IN, Allen PD, Franzini-Armstrong C, Knollmann BC.

Proc Natl Acad Sci U S A. 2009 May 5;106(18):7636-41. doi: 10.1073/pnas.0902919106. Epub 2009 Apr 21.

6.

Molecular evolution of the junctophilin gene family.

Garbino A, van Oort RJ, Dixit SS, Landstrom AP, Ackerman MJ, Wehrens XH.

Physiol Genomics. 2009 May 13;37(3):175-86. doi: 10.1152/physiolgenomics.00017.2009. Epub 2009 Mar 24.

7.

Mutations in JPH2-encoded junctophilin-2 associated with hypertrophic cardiomyopathy in humans.

Landstrom AP, Weisleder N, Batalden KB, Bos JM, Tester DJ, Ommen SR, Wehrens XH, Claycomb WC, Ko JK, Hwang M, Pan Z, Ma J, Ackerman MJ.

J Mol Cell Cardiol. 2007 Jun;42(6):1026-35. Epub 2007 Apr 18.

8.

Mutation of junctophilin type 2 associated with hypertrophic cardiomyopathy.

Matsushita Y, Furukawa T, Kasanuki H, Nishibatake M, Kurihara Y, Ikeda A, Kamatani N, Takeshima H, Matsuoka R.

J Hum Genet. 2007;52(6):543-8. Epub 2007 May 3.

PMID:
17476457
9.

Intermolecular failure of L-type Ca2+ channel and ryanodine receptor signaling in hypertrophy.

Xu M, Zhou P, Xu SM, Liu Y, Feng X, Bai SH, Bai Y, Hao XM, Han Q, Zhang Y, Wang SQ.

PLoS Biol. 2007 Feb;5(2):e21.

10.

Enhancing and confirming the specificity of RNAi experiments.

Cullen BR.

Nat Methods. 2006 Sep;3(9):677-81. Review.

PMID:
16929311
11.

Orphaned ryanodine receptors in the failing heart.

Song LS, Sobie EA, McCulle S, Lederer WJ, Balke CW, Cheng H.

Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4305-10. Epub 2006 Mar 6.

12.

Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression.

Wehrens XH, Lehnart SE, Reiken S, Vest JA, Wronska A, Marks AR.

Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):511-8. Epub 2006 Jan 6.

13.

Ryanodine receptor-targeted anti-arrhythmic therapy.

Wehrens XH, Lehnart SE, Marks AR.

Ann N Y Acad Sci. 2005 Jun;1047:366-75. Review.

PMID:
16093511
14.

Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.

Coumoul X, Shukla V, Li C, Wang RH, Deng CX.

Nucleic Acids Res. 2005 Jun 24;33(11):e102.

15.

Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies.

Minamisawa S, Oshikawa J, Takeshima H, Hoshijima M, Wang Y, Chien KR, Ishikawa Y, Matsuoka R.

Biochem Biophys Res Commun. 2004 Dec 17;325(3):852-6.

PMID:
15541368
16.

Cardiac excitation-contraction coupling.

Bers DM.

Nature. 2002 Jan 10;415(6868):198-205. Review.

PMID:
11805843
17.

Deficiency of triad junction and contraction in mutant skeletal muscle lacking junctophilin type 1.

Ito K, Komazaki S, Sasamoto K, Yoshida M, Nishi M, Kitamura K, Takeshima H.

J Cell Biol. 2001 Sep 3;154(5):1059-67.

18.

Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein.

Sohal DS, Nghiem M, Crackower MA, Witt SA, Kimball TR, Tymitz KM, Penninger JM, Molkentin JD.

Circ Res. 2001 Jul 6;89(1):20-5.

19.

Junctophilins: a novel family of junctional membrane complex proteins.

Takeshima H, Komazaki S, Nishi M, Iino M, Kangawa K.

Mol Cell. 2000 Jul;6(1):11-22.

20.

Characterization of human junctophilin subtype genes.

Nishi M, Mizushima A, Nakagawara Ki, Takeshima H.

Biochem Biophys Res Commun. 2000 Jul 14;273(3):920-7.

PMID:
10891348

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