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Items: 1 to 20 of 72

1.

Consumer perceptions of direct-to-consumer personalized genomic risk assessments.

Bloss CS, Ornowski L, Silver E, Cargill M, Vanier V, Schork NJ, Topol EJ.

Genet Med. 2010 Sep;12(9):556-66. doi: 10.1097/GIM.0b013e3181eb51c6.

PMID:
20717041
2.

Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors.

Andersen JN, Sathyanarayanan S, Di Bacco A, Chi A, Zhang T, Chen AH, Dolinski B, Kraus M, Roberts B, Arthur W, Klinghoffer RA, Gargano D, Li L, Feldman I, Lynch B, Rush J, Hendrickson RC, Blume-Jensen P, Paweletz CP.

Sci Transl Med. 2010 Aug 4;2(43):43ra55. doi: 10.1126/scitranslmed.3001065.

3.

Missing heritability in genome-wide association study research.

Vineis P, Pearce N.

Nat Rev Genet. 2010 Aug;11(8):589. doi: 10.1038/nrg2809-c2. No abstract available.

PMID:
20634813
4.

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries.

Park JH, Wacholder S, Gail MH, Peters U, Jacobs KB, Chanock SJ, Chatterjee N.

Nat Genet. 2010 Jul;42(7):570-5. doi: 10.1038/ng.610. Epub 2010 Jun 20.

5.

Human behavioral informatics in genetic studies of neuropsychiatric disease: multivariate profile-based analysis.

Bloss CS, Schiabor KM, Schork NJ.

Brain Res Bull. 2010 Sep 30;83(3-4):177-88. doi: 10.1016/j.brainresbull.2010.04.012. Epub 2010 Apr 28.

6.

Future health applications of genomics: priorities for communication, behavioral, and social sciences research.

McBride CM, Bowen D, Brody LC, Condit CM, Croyle RT, Gwinn M, Khoury MJ, Koehly LM, Korf BR, Marteau TM, McLeroy K, Patrick K, Valente TW.

Am J Prev Med. 2010 May;38(5):556-65. doi: 10.1016/j.amepre.2010.01.027.

7.

DNA, drugs and chariots: on a decade of pharmacogenomics at the US FDA.

Lesko LJ, Zineh I.

Pharmacogenomics. 2010 Apr;11(4):507-12. doi: 10.2217/pgs.10.16.

8.

Retrospective. Marshall Warren Nirenberg (1927-2010).

Leder P.

Science. 2010 Feb 19;327(5968):972. doi: 10.1126/science.1187484. No abstract available.

PMID:
20167780
9.

Toward an Alzheimer's disease diagnosis via high-resolution blood gene expression.

Fehlbaum-Beurdeley P, Jarrige-Le Prado AC, Pallares D, Carrière J, Guihal C, Soucaille C, Rouet F, Drouin D, Sol O, Jordan H, Wu D, Lei L, Einstein R, Schweighoffer F, Bracco L.

Alzheimers Dement. 2010 Jan;6(1):25-38. doi: 10.1016/j.jalz.2009.07.001.

PMID:
20129318
10.

Diagnostic classification of schizophrenia by neural network analysis of blood-based gene expression signatures.

Takahashi M, Hayashi H, Watanabe Y, Sawamura K, Fukui N, Watanabe J, Kitajima T, Yamanouchi Y, Iwata N, Mizukami K, Hori T, Shimoda K, Ujike H, Ozaki N, Iijima K, Takemura K, Aoshima H, Someya T.

Schizophr Res. 2010 Jun;119(1-3):210-8. doi: 10.1016/j.schres.2009.12.024. Epub 2010 Jan 18.

PMID:
20083392
11.

Genomic and personalized medicine: foundations and applications.

Ginsburg GS, Willard HF.

Transl Res. 2009 Dec;154(6):277-87. doi: 10.1016/j.trsl.2009.09.005. Epub 2009 Oct 1. Review.

PMID:
19931193
12.

Gene expression changes in blood as a putative biomarker for Huntington's disease.

Lovrecic L, Kastrin A, Kobal J, Pirtosek Z, Krainc D, Peterlin B.

Mov Disord. 2009 Nov 15;24(15):2277-81. doi: 10.1002/mds.22477.

PMID:
19844910
13.

Finding the missing heritability of complex diseases.

Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, Rotimi CN, Slatkin M, Valle D, Whittemore AS, Boehnke M, Clark AG, Eichler EE, Gibson G, Haines JL, Mackay TF, McCarroll SA, Visscher PM.

Nature. 2009 Oct 8;461(7265):747-53. doi: 10.1038/nature08494. Review.

14.

An agenda for personalized medicine.

Ng PC, Murray SS, Levy S, Venter JC.

Nature. 2009 Oct 8;461(7265):724-6. doi: 10.1038/461724a. No abstract available.

PMID:
19812653
15.

Telomere biology in healthy aging and disease.

Oeseburg H, de Boer RA, van Gilst WH, van der Harst P.

Pflugers Arch. 2010 Jan;459(2):259-68. doi: 10.1007/s00424-009-0728-1. Epub 2009 Sep 10. Review.

16.

The role of genetic variation in the causation of mental illness: an evolution-informed framework.

Uher R.

Mol Psychiatry. 2009 Dec;14(12):1072-82. doi: 10.1038/mp.2009.85. Epub 2009 Aug 25. Review.

PMID:
19704409
17.

Genetic variation in healthy oldest-old.

Halaschek-Wiener J, Amirabbasi-Beik M, Monfared N, Pieczyk M, Sailer C, Kollar A, Thomas R, Agalaridis G, Yamada S, Oliveira L, Collins JA, Meneilly G, Marra MA, Madden KM, Le ND, Connors JM, Brooks-Wilson AR.

PLoS One. 2009 Aug 14;4(8):e6641. doi: 10.1371/journal.pone.0006641.

18.

The HapMap and genome-wide association studies in diagnosis and therapy.

Manolio TA, Collins FS.

Annu Rev Med. 2009;60:443-56. doi: 10.1146/annurev.med.60.061907.093117. Review.

19.

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder.

International Schizophrenia Consortium, Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Sklar P.

Nature. 2009 Aug 6;460(7256):748-52. doi: 10.1038/nature08185. Epub 2009 Jul 1.

20.

Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.

Risch N, Herrell R, Lehner T, Liang KY, Eaves L, Hoh J, Griem A, Kovacs M, Ott J, Merikangas KR.

JAMA. 2009 Jun 17;301(23):2462-71. doi: 10.1001/jama.2009.878. Erratum in: JAMA. 2009 Aug 5;302(5):492.

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