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Items: 1 to 20 of 118


Oxidative stress, inflammation, and cancer: how are they linked?

Reuter S, Gupta SC, Chaturvedi MM, Aggarwal BB.

Free Radic Biol Med. 2010 Dec 1;49(11):1603-16. doi: 10.1016/j.freeradbiomed.2010.09.006. Epub 2010 Sep 16. Review.


The origin of the autophagosomal membrane.

Tooze SA, Yoshimori T.

Nat Cell Biol. 2010 Sep;12(9):831-5. doi: 10.1038/ncb0910-831.


Eaten alive: a history of macroautophagy.

Yang Z, Klionsky DJ.

Nat Cell Biol. 2010 Sep;12(9):814-22. doi: 10.1038/ncb0910-814. Review.


Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.

Matsunaga K, Morita E, Saitoh T, Akira S, Ktistakis NT, Izumi T, Noda T, Yoshimori T.

J Cell Biol. 2010 Aug 23;190(4):511-21. doi: 10.1083/jcb.200911141. Epub 2010 Aug 16.


Plasma membrane contributes to the formation of pre-autophagosomal structures.

Ravikumar B, Moreau K, Jahreiss L, Puri C, Rubinsztein DC.

Nat Cell Biol. 2010 Aug;12(8):747-57. doi: 10.1038/ncb2078. Epub 2010 Jul 18. Erratum in: Nat Cell Biol. 2010 Oct;12(10):1021.


The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis.

Walsh CM, Edinger AL.

Immunol Rev. 2010 Jul;236:95-109. doi: 10.1111/j.1600-065X.2010.00919.x. Review.


Overview of macroautophagy regulation in mammalian cells.

Mehrpour M, Esclatine A, Beau I, Codogno P.

Cell Res. 2010 Jul;20(7):748-62. doi: 10.1038/cr.2010.82. Epub 2010 Jun 15. Review.


Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells.

Suen DF, Narendra DP, Tanaka A, Manfredi G, Youle RJ.

Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11835-40. doi: 10.1073/pnas.0914569107. Epub 2010 Jun 14.


Autophagy regulates keratin 8 homeostasis in mammary epithelial cells and in breast tumors.

Kongara S, Kravchuk O, Teplova I, Lozy F, Schulte J, Moore D, Barnard N, Neumann CA, White E, Karantza V.

Mol Cancer Res. 2010 Jun;8(6):873-84. doi: 10.1158/1541-7786.MCR-09-0494. Epub 2010 Jun 8.


Termination of autophagy and reformation of lysosomes regulated by mTOR.

Yu L, McPhee CK, Zheng L, Mardones GA, Rong Y, Peng J, Mi N, Zhao Y, Liu Z, Wan F, Hailey DW, Oorschot V, Klumperman J, Baehrecke EH, Lenardo MJ.

Nature. 2010 Jun 17;465(7300):942-6. doi: 10.1038/nature09076. Epub 2010 Jun 6.


Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation.

Polson HE, de Lartigue J, Rigden DJ, Reedijk M, Urbé S, Clague MJ, Tooze SA.

Autophagy. 2010 May;6(4):506-22. doi: 10.4161/auto.6.4.11863. Epub 2010 May 16.


Mitochondria supply membranes for autophagosome biogenesis during starvation.

Hailey DW, Rambold AS, Satpute-Krishnan P, Mitra K, Sougrat R, Kim PK, Lippincott-Schwartz J.

Cell. 2010 May 14;141(4):656-67. doi: 10.1016/j.cell.2010.04.009.


Not all autophagy membranes are created equal.

McEwan DG, Dikic I.

Cell. 2010 May 14;141(4):564-6. doi: 10.1016/j.cell.2010.04.030.


The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond.

Funderburk SF, Wang QJ, Yue Z.

Trends Cell Biol. 2010 Jun;20(6):355-62. doi: 10.1016/j.tcb.2010.03.002. Epub 2010 Mar 29. Review.


The role of membrane proteins in mammalian autophagy.

Tooze SA.

Semin Cell Dev Biol. 2010 Sep;21(7):677-82. doi: 10.1016/j.semcdb.2010.03.007. Epub 2010 Mar 27. Review.


Nuclear location of an endogenously expressed antigen, EBNA1, restricts access to macroautophagy and the range of CD4 epitope display.

Leung CS, Haigh TA, Mackay LK, Rickinson AB, Taylor GS.

Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2165-70. doi: 10.1073/pnas.0909448107. Epub 2010 Jan 19.


PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.

Narendra DP, Jin SM, Tanaka A, Suen DF, Gautier CA, Shen J, Cookson MR, Youle RJ.

PLoS Biol. 2010 Jan 26;8(1):e1000298. doi: 10.1371/journal.pbio.1000298.


Alternative macroautophagy.

Klionsky DJ, Lane JD.

Autophagy. 2010 Feb;6(2):201. Epub 2010 Feb 7. No abstract available.


New insights into the function of Atg9.

Webber JL, Tooze SA.

FEBS Lett. 2010 Apr 2;584(7):1319-26. doi: 10.1016/j.febslet.2010.01.020. Epub 2010 Jan 17. Review.

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