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Items: 1 to 20 of 188


Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells.

Li Y, Zhang T, Korkaya H, Liu S, Lee HF, Newman B, Yu Y, Clouthier SG, Schwartz SJ, Wicha MS, Sun D.

Clin Cancer Res. 2010 May 1;16(9):2580-90. doi: 10.1158/1078-0432.CCR-09-2937. Epub 2010 Apr 13.


Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells.

Teng Y, Wang X, Wang Y, Ma D.

Biochem Biophys Res Commun. 2010 Feb 12;392(3):373-9. doi: 10.1016/j.bbrc.2010.01.028. Epub 2010 Jan 13.


The role of cancer stem cells and the side population in epithelial ovarian cancer.

Fong MY, Kakar SS.

Histol Histopathol. 2010 Jan;25(1):113-20. doi: 10.14670/HH-25.113. Review.


Targeting breast stem cells with the cancer preventive compounds curcumin and piperine.

Kakarala M, Brenner DE, Korkaya H, Cheng C, Tazi K, Ginestier C, Liu S, Dontu G, Wicha MS.

Breast Cancer Res Treat. 2010 Aug;122(3):777-85. doi: 10.1007/s10549-009-0612-x. Epub 2009 Nov 7.


Tumour-initiating cells: challenges and opportunities for anticancer drug discovery.

Zhou BB, Zhang H, Damelin M, Geles KG, Grindley JC, Dirks PB.

Nat Rev Drug Discov. 2009 Oct;8(10):806-23. doi: 10.1038/nrd2137. Review.


Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission.

Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K.

Cancer Res. 2009 Oct 1;69(19):7507-11. doi: 10.1158/0008-5472.CAN-09-2994. Epub 2009 Sep 14. Erratum in: Cancer Res. 2009 Nov 15;69(22):8832.


Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling.

Korkaya H, Paulson A, Charafe-Jauffret E, Ginestier C, Brown M, Dutcher J, Clouthier SG, Wicha MS.

PLoS Biol. 2009 Jun 2;7(6):e1000121. doi: 10.1371/journal.pbio.1000121. Epub 2009 Jun 2.


(-)-Epigallocatechin-3-gallate inhibits Hsp90 function by impairing Hsp90 association with cochaperones in pancreatic cancer cell line Mia Paca-2.

Li Y, Zhang T, Jiang Y, Lee HF, Schwartz SJ, Sun D.

Mol Pharm. 2009 Jul-Aug;6(4):1152-9. doi: 10.1021/mp900037p.


SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma.

Son MJ, Woolard K, Nam DH, Lee J, Fine HA.

Cell Stem Cell. 2009 May 8;4(5):440-52. doi: 10.1016/j.stem.2009.03.003.


Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials.

Bishayee A.

Cancer Prev Res (Phila). 2009 May;2(5):409-18. doi: 10.1158/1940-6207.CAPR-08-0160. Epub 2009 Apr 28. Review.


Pancreatic cancer stem cells and relevance to cancer treatments.

Bednar F, Simeone DM.

J Cell Biochem. 2009 May 1;107(1):40-5. doi: 10.1002/jcb.22093. Review.


Cellular signaling perturbation by natural products.

Sarkar FH, Li Y, Wang Z, Kong D.

Cell Signal. 2009 Nov;21(11):1541-7. doi: 10.1016/j.cellsig.2009.03.009. Epub 2009 Mar 16. Review.


The Notch signaling pathway: transcriptional regulation at Notch target genes.

Borggrefe T, Oswald F.

Cell Mol Life Sci. 2009 May;66(10):1631-46. doi: 10.1007/s00018-009-8668-7. Review.


Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model.

Chien AJ, Moore EC, Lonsdorf AS, Kulikauskas RM, Rothberg BG, Berger AJ, Major MB, Hwang ST, Rimm DL, Moon RT.

Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1193-8. doi: 10.1073/pnas.0811902106. Epub 2009 Jan 14.


Cancer stem cells: how can we target them?

Ischenko I, Seeliger H, Schaffer M, Jauch KW, Bruns CJ.

Curr Med Chem. 2008;15(30):3171-84. Review.


Soy isoflavone genistein upregulates epithelial adhesion molecule E-cadherin expression and attenuates beta-catenin signaling in mammary epithelial cells.

Su Y, Simmen RC.

Carcinogenesis. 2009 Feb;30(2):331-9. doi: 10.1093/carcin/bgn279. Epub 2008 Dec 10.


Promotion of the self-renewal capacity of human acute leukemia cells by Wnt3A.

Kawaguchi-Ihara N, Murohashi I, Nara N, Tohda S.

Anticancer Res. 2008 Sep-Oct;28(5A):2701-4.


Emerging role of Notch in stem cells and cancer.

Wang Z, Li Y, Banerjee S, Sarkar FH.

Cancer Lett. 2009 Jun 28;279(1):8-12. doi: 10.1016/j.canlet.2008.09.030. Epub 2008 Nov 20. Review.


Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300.

Ryu MJ, Cho M, Song JY, Yun YS, Choi IW, Kim DE, Park BS, Oh S.

Biochem Biophys Res Commun. 2008 Dec 26;377(4):1304-8. doi: 10.1016/j.bbrc.2008.10.171. Epub 2008 Nov 10.


Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis.

Shankar S, Ganapathy S, Srivastava RK.

Clin Cancer Res. 2008 Nov 1;14(21):6855-66. doi: 10.1158/1078-0432.CCR-08-0903.

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