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Items: 17

1.

Direct cell reprogramming is a stochastic process amenable to acceleration.

Hanna J, Saha K, Pando B, van Zon J, Lengner CJ, Creyghton MP, van Oudenaarden A, Jaenisch R.

Nature. 2009 Dec 3;462(7273):595-601. doi: 10.1038/nature08592. Epub 2009 Nov 8.

2.

Senescence impairs successful reprogramming to pluripotent stem cells.

Banito A, Rashid ST, Acosta JC, Li S, Pereira CF, Geti I, Pinho S, Silva JC, Azuara V, Walsh M, Vallier L, Gil J.

Genes Dev. 2009 Sep 15;23(18):2134-9. doi: 10.1101/gad.1811609. Epub 2009 Aug 20.

3.

Suppression of induced pluripotent stem cell generation by the p53-p21 pathway.

Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, Nakagawa M, Okita K, Yamanaka S.

Nature. 2009 Aug 27;460(7259):1132-5. doi: 10.1038/nature08235. Epub 2009 Aug 9.

4.

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells.

Utikal J, Polo JM, Stadtfeld M, Maherali N, Kulalert W, Walsh RM, Khalil A, Rheinwald JG, Hochedlinger K.

Nature. 2009 Aug 27;460(7259):1145-8. doi: 10.1038/nature08285. Epub 2009 Aug 9.

5.

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity.

Marión RM, Strati K, Li H, Murga M, Blanco R, Ortega S, Fernandez-Capetillo O, Serrano M, Blasco MA.

Nature. 2009 Aug 27;460(7259):1149-53. doi: 10.1038/nature08287. Epub 2009 Aug 9.

6.

The Ink4/Arf locus is a barrier for iPS cell reprogramming.

Li H, Collado M, Villasante A, Strati K, Ortega S, Cañamero M, Blasco MA, Serrano M.

Nature. 2009 Aug 27;460(7259):1136-9. doi: 10.1038/nature08290. Epub 2009 Aug 9.

7.

Linking the p53 tumour suppressor pathway to somatic cell reprogramming.

Kawamura T, Suzuki J, Wang YV, Menendez S, Morera LB, Raya A, Wahl GM, Izpisúa Belmonte JC.

Nature. 2009 Aug 27;460(7259):1140-4. doi: 10.1038/nature08311. Epub 2009 Aug 9.

8.

p53-Induced apoptosis and inhibitors of p53.

Nayak SK, Panesar PS, Kumar H.

Curr Med Chem. 2009;16(21):2627-40. Review.

PMID:
19601800
9.

Inhibition of p53 transcriptional activity: a potential target for future development of therapeutic strategies for primary demyelination.

Li J, Ghiani CA, Kim JY, Liu A, Sandoval J, DeVellis J, Casaccia-Bonnefil P.

J Neurosci. 2008 Jun 11;28(24):6118-27. doi: 10.1523/JNEUROSCI.0184-08.2008.

10.

Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300.

Zeng L, Zhang Q, Gerona-Navarro G, Moshkina N, Zhou MM.

Structure. 2008 Apr;16(4):643-52. doi: 10.1016/j.str.2008.01.010.

11.

Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation.

Strom E, Sathe S, Komarov PG, Chernova OB, Pavlovska I, Shyshynova I, Bosykh DA, Burdelya LG, Macklis RM, Skaliter R, Komarova EA, Gudkov AV.

Nat Chem Biol. 2006 Sep;2(9):474-9. Epub 2006 Jul 23.

PMID:
16862141
12.

Target structure-based discovery of small molecules that block human p53 and CREB binding protein association.

Sachchidanand, Resnick-Silverman L, Yan S, Mutjaba S, Liu WJ, Zeng L, Manfredi JJ, Zhou MM.

Chem Biol. 2006 Jan;13(1):81-90.

13.

Rapid and quantitative cyclization of multiple peptide loops onto synthetic scaffolds for structural mimicry of protein surfaces.

Timmerman P, Beld J, Puijk WC, Meloen RH.

Chembiochem. 2005 May;6(5):821-4. No abstract available.

PMID:
15812852
14.

Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.

Mujtaba S, He Y, Zeng L, Yan S, Plotnikova O, Sachchidanand, Sanchez R, Zeleznik-Le NJ, Ronai Z, Zhou MM.

Mol Cell. 2004 Jan 30;13(2):251-63.

15.

p300/CBP proteins: HATs for transcriptional bridges and scaffolds.

Chan HM, La Thangue NB.

J Cell Sci. 2001 Jul;114(Pt 13):2363-73. Review.

16.

CBP/p300 in cell growth, transformation, and development.

Goodman RH, Smolik S.

Genes Dev. 2000 Jul 1;14(13):1553-77. Review. No abstract available.

17.

Nuclear protein CBP is a coactivator for the transcription factor CREB.

Kwok RP, Lundblad JR, Chrivia JC, Richards JP, Bächinger HP, Brennan RG, Roberts SG, Green MR, Goodman RH.

Nature. 1994 Jul 21;370(6486):223-6.

PMID:
7913207

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