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Items: 1 to 20 of 30

1.

Structural basis for negative cooperativity in growth factor binding to an EGF receptor.

Alvarado D, Klein DE, Lemmon MA.

Cell. 2010 Aug 20;142(4):568-79. doi: 10.1016/j.cell.2010.07.015.

2.

Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data.

Chen WW, Schoeberl B, Jasper PJ, Niepel M, Nielsen UB, Lauffenburger DA, Sorger PK.

Mol Syst Biol. 2009;5:239. doi: 10.1038/msb.2008.74. Epub 2009 Jan 20.

3.

Linear combinations of docking affinities explain quantitative differences in RTK signaling.

Gordus A, Krall JA, Beyer EM, Kaushansky A, Wolf-Yadlin A, Sevecka M, Chang BH, Rush J, MacBeath G.

Mol Syst Biol. 2009;5:235. doi: 10.1038/msb.2008.72. Epub 2009 Jan 20.

4.

Ligand-induced ErbB receptor dimerization.

Lemmon MA.

Exp Cell Res. 2009 Feb 15;315(4):638-48. doi: 10.1016/j.yexcr.2008.10.024. Epub 2008 Oct 31. Review.

5.

Epidermal growth factor-induced ovarian carcinoma cell migration is associated with JAK2/STAT3 signals and changes in the abundance and localization of alpha6beta1 integrin.

Colomiere M, Findlay J, Ackland L, Ahmed N.

Int J Biochem Cell Biol. 2009 May;41(5):1034-45. doi: 10.1016/j.biocel.2008.09.018. Epub 2008 Sep 27.

PMID:
18930836
6.

Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system.

Macdonald JL, Pike LJ.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):112-7. doi: 10.1073/pnas.0707080105. Epub 2007 Dec 28. Erratum in: Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9129.

7.

Cell death of MCF-7 human breast cancer cells induced by EGFR activation in the absence of other growth factors.

Garcia R, Franklin RA, McCubrey JA.

Cell Cycle. 2006 Aug;5(16):1840-6. Epub 2006 Aug 15.

PMID:
16861904
8.

A comprehensive pathway map of epidermal growth factor receptor signaling.

Oda K, Matsuoka Y, Funahashi A, Kitano H.

Mol Syst Biol. 2005;1:2005.0010. Epub 2005 May 25.

9.

Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors.

Shoyab M, De Larco JE, Todaro GJ.

Nature. 1979 May 31;279(5712):387-91.

PMID:
16068160
10.
11.

Signal transduction and oncogenesis by ErbB/HER receptors.

Marmor MD, Skaria KB, Yarden Y.

Int J Radiat Oncol Biol Phys. 2004 Mar 1;58(3):903-13. Review.

PMID:
14967450
12.

A structure-based model for ligand binding and dimerization of EGF receptors.

Klein P, Mattoon D, Lemmon MA, Schlessinger J.

Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):929-34. Epub 2004 Jan 19. Erratum in: Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):11176.

13.

SH2 and PTB domains in tyrosine kinase signaling.

Schlessinger J, Lemmon MA.

Sci STKE. 2003 Jul 15;2003(191):RE12. Review.

PMID:
12865499
15.

Computational modeling of the EGF-receptor system: a paradigm for systems biology.

Wiley HS, Shvartsman SY, Lauffenburger DA.

Trends Cell Biol. 2003 Jan;13(1):43-50. Review.

PMID:
12480339
16.

The EGF/ErbB receptor family and apoptosis.

Danielsen AJ, Maihle NJ.

Growth Factors. 2002 Mar;20(1):1-15. Review.

PMID:
11999214
17.

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors.

Schoeberl B, Eichler-Jonsson C, Gilles ED, Müller G.

Nat Biotechnol. 2002 Apr;20(4):370-5.

PMID:
11923843
18.

Cell signaling by receptor tyrosine kinases.

Schlessinger J.

Cell. 2000 Oct 13;103(2):211-25. Review. No abstract available.

19.

Up-regulation of alpha 2 beta 1 integrin cell-surface expression protects A431 cells from epidermal growth factor-induced apoptosis.

Smida Rezgui S, Honore S, Rognoni JB, Martin PM, Penel C.

Int J Cancer. 2000 Aug 1;87(3):360-7.

20.

Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo.

Grandis JR, Drenning SD, Zeng Q, Watkins SC, Melhem MF, Endo S, Johnson DE, Huang L, He Y, Kim JD.

Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4227-32.

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