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Dis3-like 1: a novel exoribonuclease associated with the human exosome.

Staals RH, Bronkhorst AW, Schilders G, Slomovic S, Schuster G, Heck AJ, Raijmakers R, Pruijn GJ.

EMBO J. 2010 Jul 21;29(14):2358-67. doi: 10.1038/emboj.2010.122. Epub 2010 Jun 8.


The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.

Tomecki R, Kristiansen MS, Lykke-Andersen S, Chlebowski A, Larsen KM, Szczesny RJ, Drazkowska K, Pastula A, Andersen JS, Stepien PP, Dziembowski A, Jensen TH.

EMBO J. 2010 Jul 21;29(14):2342-57. doi: 10.1038/emboj.2010.121. Epub 2010 Jun 8.


The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation.

Bonneau F, Basquin J, Ebert J, Lorentzen E, Conti E.

Cell. 2009 Oct 30;139(3):547-59. doi: 10.1016/j.cell.2009.08.042.


Analysis of Dom34 and its function in no-go decay.

Passos DO, Doma MK, Shoemaker CJ, Muhlrad D, Green R, Weissman J, Hollien J, Parker R.

Mol Biol Cell. 2009 Jul;20(13):3025-32. doi: 10.1091/mbc.E09-01-0028. Epub 2009 May 6.


The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome.

Schneider C, Leung E, Brown J, Tollervey D.

Nucleic Acids Res. 2009 Mar;37(4):1127-40. doi: 10.1093/nar/gkn1020. Epub 2009 Jan 7.


The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.

Schaeffer D, Tsanova B, Barbas A, Reis FP, Dastidar EG, Sanchez-Rotunno M, Arraiano CM, van Hoof A.

Nat Struct Mol Biol. 2009 Jan;16(1):56-62. doi: 10.1038/nsmb.1528. Epub 2008 Dec 7.


SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells.

Eberle AB, Lykke-Andersen S, Mühlemann O, Jensen TH.

Nat Struct Mol Biol. 2009 Jan;16(1):49-55. doi: 10.1038/nsmb.1530. Epub 2008 Dec 7.


Endonucleolytic RNA cleavage by a eukaryotic exosome.

Lebreton A, Tomecki R, Dziembowski A, Séraphin B.

Nature. 2008 Dec 18;456(7224):993-6. doi: 10.1038/nature07480. Epub 2008 Dec 7.


SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan.

Huntzinger E, Kashima I, Fauser M, Saulière J, Izaurralde E.

RNA. 2008 Dec;14(12):2609-17. doi: 10.1261/rna.1386208. Epub 2008 Oct 30.


Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family.

Lorentzen E, Basquin J, Tomecki R, Dziembowski A, Conti E.

Mol Cell. 2008 Mar 28;29(6):717-28. doi: 10.1016/j.molcel.2008.02.018.


Reconstitution, activities, and structure of the eukaryotic RNA exosome.

Liu Q, Greimann JC, Lima CD.

Cell. 2006 Dec 15;127(6):1223-37. Erratum in: Cell. 2007 Oct 5;131(1):188-9.


A single subunit, Dis3, is essentially responsible for yeast exosome core activity.

Dziembowski A, Lorentzen E, Conti E, Séraphin B.

Nat Struct Mol Biol. 2007 Jan;14(1):15-22. Epub 2006 Dec 17.


Structural basis for processivity and single-strand specificity of RNase II.

Zuo Y, Vincent HA, Zhang J, Wang Y, Deutscher MP, Malhotra A.

Mol Cell. 2006 Oct 6;24(1):149-56. Epub 2006 Sep 21.


Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA-bound complex.

Frazão C, McVey CE, Amblar M, Barbas A, Vonrhein C, Arraiano CM, Carrondo MA.

Nature. 2006 Sep 7;443(7107):110-4.


Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

Hollien J, Weissman JS.

Science. 2006 Jul 7;313(5783):104-7.


Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome.

Orban TI, Izaurralde E.

RNA. 2005 Apr;11(4):459-69. Epub 2005 Feb 9.


AtXRN4 degrades mRNA in Arabidopsis and its substrates include selected miRNA targets.

Souret FF, Kastenmayer JP, Green PJ.

Mol Cell. 2004 Jul 23;15(2):173-83.

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