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Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion.

Sharma-Walia N, Paul AG, Bottero V, Sadagopan S, Veettil MV, Kerur N, Chandran B.

PLoS Pathog. 2010 Feb 12;6(2):e1000777. doi: 10.1371/journal.ppat.1000777.


Inhibition of the phosphatidylinositol 3-kinase-Akt pathway enhances gamma-2 herpesvirus lytic replication and facilitates reactivation from latency.

Peng L, Wu TT, Tchieu JH, Feng J, Brown HJ, Feng J, Li X, Qi J, Deng H, Vivanco I, Mellinghoff IK, Jamieson C, Sun R.

J Gen Virol. 2010 Feb;91(Pt 2):463-9. doi: 10.1099/vir.0.015073-0. Epub 2009 Oct 28.


FLIP-mediated autophagy regulation in cell death control.

Lee JS, Li Q, Lee JY, Lee SH, Jeong JH, Lee HR, Chang H, Zhou FC, Gao SJ, Liang C, Jung JU.

Nat Cell Biol. 2009 Nov;11(11):1355-62. doi: 10.1038/ncb1980. Epub 2009 Oct 18.


Role of virus-encoded microRNAs in herpesvirus biology.

Boss IW, Plaisance KB, Renne R.

Trends Microbiol. 2009 Dec;17(12):544-53. doi: 10.1016/j.tim.2009.09.002. Epub 2009 Oct 12. Review.


Angiogenin is involved in lung adenocarcinoma cell proliferation and angiogenesis.

Yuan Y, Wang F, Liu XH, Gong DJ, Cheng HZ, Huang SD.

Lung Cancer. 2009 Oct;66(1):28-36. doi: 10.1016/j.lungcan.2008.12.027. Epub 2009 May 6.


Neamine inhibits prostate cancer growth by suppressing angiogenin-mediated rRNA transcription.

Ibaragi S, Yoshioka N, Li S, Hu MG, Hirukawa S, Sadow PM, Hu GF.

Clin Cancer Res. 2009 Mar 15;15(6):1981-8. doi: 10.1158/1078-0432.CCR-08-2593. Epub 2009 Mar 10.


Modulation of the immune system by Kaposi's sarcoma-associated herpesvirus.

Aresté C, Blackbourn DJ.

Trends Microbiol. 2009 Mar;17(3):119-29. doi: 10.1016/j.tim.2008.12.001. Epub 2009 Feb 18. Review.


Kaposi's sarcoma-associated herpesvirus upregulates angiogenin during infection of human dermal microvascular endothelial cells, which induces 45S rRNA synthesis, antiapoptosis, cell proliferation, migration, and angiogenesis.

Sadagopan S, Sharma-Walia N, Veettil MV, Bottero V, Levine R, Vart RJ, Chandran B.

J Virol. 2009 Apr;83(7):3342-64. doi: 10.1128/JVI.02052-08. Epub 2009 Jan 21.


Kaposi's sarcoma-associated herpesvirus confers a survival advantage to endothelial cells.

Wang L, Damania B.

Cancer Res. 2008 Jun 15;68(12):4640-8. doi: 10.1158/0008-5472.CAN-07-5988.


KSHV infection and the pathogenesis of Kaposi's sarcoma.

Ganem D.

Annu Rev Pathol. 2006;1:273-96. Review.


Development of a fluorescence-based assay to screen antiviral drugs against Kaposi's sarcoma associated herpesvirus.

Nun TK, Kroll DJ, Oberlies NH, Soejarto DD, Case RJ, Piskaut P, Matainaho T, Hilscher C, Wang L, Dittmer DP, Gao SJ, Damania B.

Mol Cancer Ther. 2007 Aug;6(8):2360-70.


The Kaposi's sarcoma-associated herpesvirus LANA protein stabilizes and activates c-Myc.

Liu J, Martin HJ, Liao G, Hayward SD.

J Virol. 2007 Oct;81(19):10451-9. Epub 2007 Jul 18.


Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6 and G-protein-coupled receptor regulate angiopoietin-2 expression in lymphatic endothelial cells.

Vart RJ, Nikitenko LL, Lagos D, Trotter MW, Cannon M, Bourboulia D, Gratrix F, Takeuchi Y, Boshoff C.

Cancer Res. 2007 May 1;67(9):4042-51.


Angiogenin-induced protein kinase B/Akt activation is necessary for angiogenesis but is independent of nuclear translocation of angiogenin in HUVE cells.

Kim HM, Kang DK, Kim HY, Kang SS, Chang SI.

Biochem Biophys Res Commun. 2007 Jan 12;352(2):509-13. Epub 2006 Nov 17.


Induction of spindle cell morphology in human vascular endothelial cells by human herpesvirus 8-encoded viral FLICE inhibitory protein K13.

Matta H, Surabhi RM, Zhao J, Punj V, Sun Q, Schamus S, Mazzacurati L, Chaudhary PM.

Oncogene. 2007 Mar 8;26(11):1656-60. Epub 2006 Aug 28.


Cyclooxygenase 2 induced by Kaposi's sarcoma-associated herpesvirus early during in vitro infection of target cells plays a role in the maintenance of latent viral gene expression.

Sharma-Walia N, Raghu H, Sadagopan S, Sivakumar R, Veettil MV, Naranatt PP, Smith MM, Chandran B.

J Virol. 2006 Jul;80(13):6534-52.

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