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Sp1 binds to the external promoter of the p73 gene and induces the expression of TAp73gamma in lung cancer.

Logotheti S, Michalopoulos I, Sideridou M, Daskalos A, Kossida S, Spandidos DA, Field JK, Vojtesek B, Liloglou T, Gorgoulis V, Zoumpourlis V.

FEBS J. 2010 Jul;277(14):3014-27. doi: 10.1111/j.1742-4658.2010.07710.x. Epub 2010 Jun 7.


Pharmacological reactivation of mutant p53: from protein structure to the cancer patient.

Wiman KG.

Oncogene. 2010 Jul 29;29(30):4245-52. doi: 10.1038/onc.2010.188. Epub 2010 May 24. Review.


Mdm2 facilitates the association of p53 with the proteasome.

Kulikov R, Letienne J, Kaur M, Grossman SR, Arts J, Blattner C.

Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10038-43. doi: 10.1073/pnas.0911716107. Epub 2010 May 17.


RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.

Yamada C, Ozaki T, Ando K, Suenaga Y, Inoue K, Ito Y, Okoshi R, Kageyama H, Kimura H, Miyazaki M, Nakagawara A.

J Biol Chem. 2010 May 28;285(22):16693-703. doi: 10.1074/jbc.M109.055525. Epub 2010 Mar 30.


Transcriptional regulation of tumor suppressor p53 by cAMP-responsive element-binding protein/AMP-activated protein kinase complex in response to glucose deprivation.

Okoshi R, Ando K, Suenaga Y, Sang M, Kubo N, Kizaki H, Nakagawara A, Ozaki T.

Genes Cells. 2009 Dec;14(12):1429-40. doi: 10.1111/j.1365-2443.2009.01359.x. Epub 2009 Nov 20.


TATA-binding Protein (TBP)-like Protein Is Engaged in Etoposide-induced Apoptosis through Transcriptional Activation of Human TAp63 Gene.

Suenaga Y, Ozaki T, Tanaka Y, Bu Y, Kamijo T, Tokuhisa T, Nakagawara A, Tamura TA.

J Biol Chem. 2009 Dec 18;284(51):35433-40. doi: 10.1074/jbc.M109.050047.


p53 sumoylation: mechanistic insights from reconstitution studies.

Wu SY, Chiang CM.

Epigenetics. 2009 Oct 1;4(7):445-51. Epub 2009 Oct 9.


Plk1 regulates liver tumor cell death by phosphorylation of TAp63.

Komatsu S, Takenobu H, Ozaki T, Ando K, Koida N, Suenaga Y, Ichikawa T, Hishiki T, Chiba T, Iwama A, Yoshida H, Ohnuma N, Nakagawara A, Kamijo T.

Oncogene. 2009 Oct 15;28(41):3631-41. doi: 10.1038/onc.2009.216. Epub 2009 Aug 10.


Activation of p53-dependent responses in tumor cells treated with a PARC-interacting peptide.

Vitali R, Cesi V, Tanno B, Ferrari-Amorotti G, Dominici C, Calabretta B, Raschellà G.

Biochem Biophys Res Commun. 2008 Apr 4;368(2):350-6. doi: 10.1016/j.bbrc.2008.01.093. Epub 2008 Jan 28.


Inhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylation.

Koida N, Ozaki T, Yamamoto H, Ono S, Koda T, Ando K, Okoshi R, Kamijo T, Omura K, Nakagawara A.

J Biol Chem. 2008 Mar 28;283(13):8555-63. doi: 10.1074/jbc.M710608200. Epub 2008 Jan 3.


Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress.

Okoshi R, Ozaki T, Yamamoto H, Ando K, Koida N, Ono S, Koda T, Kamijo T, Nakagawara A, Kizaki H.

J Biol Chem. 2008 Feb 15;283(7):3979-87. Epub 2007 Dec 4.


ATM-dependent nuclear accumulation of IKK-alpha plays an important role in the regulation of p73-mediated apoptosis in response to cisplatin.

Yoshida K, Ozaki T, Furuya K, Nakanishi M, Kikuchi H, Yamamoto H, Ono S, Koda T, Omura K, Nakagawara A.

Oncogene. 2008 Feb 14;27(8):1183-8. Epub 2007 Aug 13.


NFBD1/MDC1 associates with p53 and regulates its function at the crossroad between cell survival and death in response to DNA damage.

Nakanishi M, Ozaki T, Yamamoto H, Hanamoto T, Kikuchi H, Furuya K, Asaka M, Delia D, Nakagawara A.

J Biol Chem. 2007 Aug 3;282(31):22993-3004. Epub 2007 May 29.


Stabilization of p73 by nuclear IkappaB kinase-alpha mediates cisplatin-induced apoptosis.

Furuya K, Ozaki T, Hanamoto T, Hosoda M, Hayashi S, Barker PA, Takano K, Matsumoto M, Nakagawara A.

J Biol Chem. 2007 Jun 22;282(25):18365-78. Epub 2007 Apr 23.


Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma.

Becker K, Marchenko ND, Maurice M, Moll UM.

Cell Death Differ. 2007 Jul;14(7):1350-60. Epub 2007 Mar 23.


C-terminal modifications regulate MDM2 dissociation and nuclear export of p53.

Carter S, Bischof O, Dejean A, Vousden KH.

Nat Cell Biol. 2007 Apr;9(4):428-35. Epub 2007 Mar 18.


Functional characterization of a new p53 mutant generated by homozygous deletion in a neuroblastoma cell line.

Nakamura Y, Ozaki T, Niizuma H, Ohira M, Kamijo T, Nakagawara A.

Biochem Biophys Res Commun. 2007 Mar 23;354(4):892-8. Epub 2007 Jan 22.


Monoubiquitylation promotes mitochondrial p53 translocation.

Marchenko ND, Wolff S, Erster S, Becker K, Moll UM.

EMBO J. 2007 Feb 21;26(4):923-34. Epub 2007 Feb 1.


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