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Items: 1 to 20 of 38

1.

Synthetic substrates for measuring activity of autophagy proteases: autophagins (Atg4).

Shu CW, Drag M, Bekes M, Zhai D, Salvesen GS, Reed JC.

Autophagy. 2010 Oct;6(7):936-47. doi: 10.4161/auto.6.7.13075. Epub 2010 Oct 19.

2.

Histopathological and neurological features of Atg4b knockout mice.

Read R, Savelieva K, Baker K, Hansen G, Vogel P.

Vet Pathol. 2011 Mar;48(2):486-94. doi: 10.1177/0300985810375810. Epub 2010 Jul 15.

PMID:
20634410
3.

Autophagy is essential for mouse sense of balance.

Mariño G, Fernández AF, Cabrera S, Lundberg YW, Cabanillas R, Rodríguez F, Salvador-Montoliu N, Vega JA, Germanà A, Fueyo A, Freije JM, López-Otín C.

J Clin Invest. 2010 Jul;120(7):2331-44. doi: 10.1172/JCI42601. Epub 2010 Jun 23.

4.

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis.

Weidberg H, Shvets E, Shpilka T, Shimron F, Shinder V, Elazar Z.

EMBO J. 2010 Jun 2;29(11):1792-802. doi: 10.1038/emboj.2010.74. Epub 2010 Apr 23.

5.

Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis.

Betin VM, Lane JD.

J Cell Sci. 2009 Jul 15;122(Pt 14):2554-66. doi: 10.1242/jcs.046250. Epub 2009 Jun 23.

6.

The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy.

Satoo K, Noda NN, Kumeta H, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.

EMBO J. 2009 May 6;28(9):1341-50. doi: 10.1038/emboj.2009.80. Epub 2009 Mar 26.

7.

Physiological pH and acidic phospholipids contribute to substrate specificity in lipidation of Atg8.

Oh-oka K, Nakatogawa H, Ohsumi Y.

J Biol Chem. 2008 Aug 8;283(32):21847-52. doi: 10.1074/jbc.M801836200. Epub 2008 Jun 10.

8.

Atg8 controls phagophore expansion during autophagosome formation.

Xie Z, Nair U, Klionsky DJ.

Mol Biol Cell. 2008 Aug;19(8):3290-8. doi: 10.1091/mbc.E07-12-1292. Epub 2008 May 28.

9.

The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy.

Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T.

Mol Biol Cell. 2008 May;19(5):2092-100. doi: 10.1091/mbc.E07-12-1257. Epub 2008 Mar 5.

10.

Developmental expression of LC3alpha and beta: absence of fibronectin or autophagy phenotype in LC3beta knockout mice.

Cann GM, Guignabert C, Ying L, Deshpande N, Bekker JM, Wang L, Zhou B, Rabinovitch M.

Dev Dyn. 2008 Jan;237(1):187-95.

11.

Autophagy: process and function.

Mizushima N.

Genes Dev. 2007 Nov 15;21(22):2861-73. Review.

12.
13.

Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3.

Mariño G, Salvador-Montoliu N, Fueyo A, Knecht E, Mizushima N, López-Otín C.

J Biol Chem. 2007 Jun 22;282(25):18573-83. Epub 2007 Apr 17.

14.

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4.

Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z.

EMBO J. 2007 Apr 4;26(7):1749-60. Epub 2007 Mar 8.

15.

Hierarchy of Atg proteins in pre-autophagosomal structure organization.

Suzuki K, Kubota Y, Sekito T, Ohsumi Y.

Genes Cells. 2007 Feb;12(2):209-18.

16.

Atg8L/Apg8L is the fourth mammalian modifier of mammalian Atg8 conjugation mediated by human Atg4B, Atg7 and Atg3.

Tanida I, Sou YS, Minematsu-Ikeguchi N, Ueno T, Kominami E.

FEBS J. 2006 Jun;273(11):2553-62.

17.

The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers.

Kumanomidou T, Mizushima T, Komatsu M, Suzuki A, Tanida I, Sou YS, Ueno T, Kominami E, Tanaka K, Yamane T.

J Mol Biol. 2006 Jan 27;355(4):612-8. Epub 2005 Nov 28.

PMID:
16325851
18.

Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy.

Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.

J Biol Chem. 2005 Dec 2;280(48):40058-65. Epub 2005 Sep 23.

19.

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice.

Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I, Ezaki J, Mizushima N, Ohsumi Y, Uchiyama Y, Kominami E, Tanaka K, Chiba T.

J Cell Biol. 2005 May 9;169(3):425-34. Epub 2005 May 2.

20.

Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains.

Kouno T, Mizuguchi M, Tanida I, Ueno T, Kanematsu T, Mori Y, Shinoda H, Hirata M, Kominami E, Kawano K.

J Biol Chem. 2005 Jul 1;280(26):24610-7. Epub 2005 Apr 27.

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