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Items: 1 to 20 of 141

1.

Endoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease.

Gentile CL, Frye M, Pagliassotti MJ.

Antioxid Redox Signal. 2011 Jul 15;15(2):505-21. doi: 10.1089/ars.2010.3790. Epub 2011 Apr 26. Review.

2.

Dietary fructose exacerbates hepatocellular injury when incorporated into a methionine-choline-deficient diet.

Pickens MK, Ogata H, Soon RK, Grenert JP, Maher JJ.

Liver Int. 2010 Sep;30(8):1229-39. doi: 10.1111/j.1478-3231.2010.02285.x. Epub 2010 Jun 8.

3.

Possible involvement and the mechanisms of excess trans-fatty acid consumption in severe NAFLD in mice.

Obara N, Fukushima K, Ueno Y, Wakui Y, Kimura O, Tamai K, Kakazu E, Inoue J, Kondo Y, Ogawa N, Sato K, Tsuduki T, Ishida K, Shimosegawa T.

J Hepatol. 2010 Aug;53(2):326-34. doi: 10.1016/j.jhep.2010.02.029. Epub 2010 Apr 22.

PMID:
20462650
4.

Endocannabinoids and their role in fatty liver disease.

Mallat A, Lotersztajn S.

Dig Dis. 2010;28(1):261-6. doi: 10.1159/000282100. Epub 2010 May 7. Review.

PMID:
20460921
5.

Role of microRNAs in non-alcoholic steatohepatitis.

Cheung O, Sanyal AJ.

Curr Pharm Des. 2010 Jun;16(17):1952-7. Review.

PMID:
20370674
6.

Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet.

Zhang YK, Yeager RL, Tanaka Y, Klaassen CD.

Toxicol Appl Pharmacol. 2010 Jun 15;245(3):326-34. doi: 10.1016/j.taap.2010.03.016. Epub 2010 Mar 27.

7.

Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice.

Miura K, Kodama Y, Inokuchi S, Schnabl B, Aoyama T, Ohnishi H, Olefsky JM, Brenner DA, Seki E.

Gastroenterology. 2010 Jul;139(1):323-34.e7. doi: 10.1053/j.gastro.2010.03.052. Epub 2010 Mar 27.

8.

Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model.

Rector RS, Thyfault JP, Uptergrove GM, Morris EM, Naples SP, Borengasser SJ, Mikus CR, Laye MJ, Laughlin MH, Booth FW, Ibdah JA.

J Hepatol. 2010 May;52(5):727-36. doi: 10.1016/j.jhep.2009.11.030. Epub 2010 Mar 4.

9.

Genetic control of de novo lipogenesis: role in diet-induced obesity.

Strable MS, Ntambi JM.

Crit Rev Biochem Mol Biol. 2010 Jun;45(3):199-214. doi: 10.3109/10409231003667500. Review.

10.

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.

Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV Jr, Alt FW, Kahn CR, Verdin E.

Nature. 2010 Mar 4;464(7285):121-5. doi: 10.1038/nature08778.

11.

Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death.

Pfaffenbach KT, Gentile CL, Nivala AM, Wang D, Wei Y, Pagliassotti MJ.

Am J Physiol Endocrinol Metab. 2010 May;298(5):E1027-35. doi: 10.1152/ajpendo.00642.2009. Epub 2010 Feb 16.

12.

Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver.

Klaassen CD, Reisman SA.

Toxicol Appl Pharmacol. 2010 Apr 1;244(1):57-65. doi: 10.1016/j.taap.2010.01.013. Epub 2010 Feb 1. Review.

13.

The anti-inflammatory effects of adiponectin are mediated via a heme oxygenase-1-dependent pathway in rat Kupffer cells.

Mandal P, Park PH, McMullen MR, Pratt BT, Nagy LE.

Hepatology. 2010 Apr;51(4):1420-9. doi: 10.1002/hep.23427.

14.

Kupffer cell and interleukin-12-dependent loss of natural killer T cells in hepatosteatosis.

Kremer M, Thomas E, Milton RJ, Perry AW, van Rooijen N, Wheeler MD, Zacks S, Fried M, Rippe RA, Hines IN.

Hepatology. 2010 Jan;51(1):130-41. doi: 10.1002/hep.23292.

15.

Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice.

Sugimoto H, Okada K, Shoda J, Warabi E, Ishige K, Ueda T, Taguchi K, Yanagawa T, Nakahara A, Hyodo I, Ishii T, Yamamoto M.

Am J Physiol Gastrointest Liver Physiol. 2010 Feb;298(2):G283-94. doi: 10.1152/ajpgi.00296.2009. Epub 2009 Nov 19.

16.

Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis.

Chowdhry S, Nazmy MH, Meakin PJ, Dinkova-Kostova AT, Walsh SV, Tsujita T, Dillon JF, Ashford ML, Hayes JD.

Free Radic Biol Med. 2010 Jan 15;48(2):357-71. doi: 10.1016/j.freeradbiomed.2009.11.007. Epub 2009 Nov 13.

PMID:
19914374
17.

Curcumin limits the fibrogenic evolution of experimental steatohepatitis.

Vizzutti F, Provenzano A, Galastri S, Milani S, Delogu W, Novo E, Caligiuri A, Zamara E, Arena U, Laffi G, Parola M, Pinzani M, Marra F.

Lab Invest. 2010 Jan;90(1):104-15. doi: 10.1038/labinvest.2009.112. Epub 2009 Nov 9.

18.

Heme oxygenase-1 protects against steatohepatitis in both cultured hepatocytes and mice.

Yu J, Chu ES, Wang R, Wang S, Wu CW, Wong VW, Chan HL, Farrell GC, Sung JJ.

Gastroenterology. 2010 Feb;138(2):694-704, 704.e1. doi: 10.1053/j.gastro.2009.09.058. Epub 2009 Oct 7.

PMID:
19818781
19.

Adiponectin knockout mice on high fat diet develop fibrosing steatohepatitis.

Asano T, Watanabe K, Kubota N, Gunji T, Omata M, Kadowaki T, Ohnishi S.

J Gastroenterol Hepatol. 2009 Oct;24(10):1669-76. doi: 10.1111/j.1440-1746.2009.06039.x.

PMID:
19788607
20.

Thioredoxin-binding protein-2 deficiency enhances methionine-choline deficient diet-induced hepatic steatosis but inhibits steatohepatitis in mice.

Ahsan MK, Okuyama H, Hoshino Y, Oka S, Masutani H, Yodoi J, Nakamura H.

Antioxid Redox Signal. 2009 Oct;11(10):2573-84. doi: 10.1089/ars.2009.2385.

PMID:
19764881

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