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Items: 1 to 20 of 60

1.

An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption.

Iqbal J, Li X, Chang BH, Chan L, Schwartz GJ, Chua SC Jr, Hussain MM.

J Lipid Res. 2010 Jul;51(7):1929-42. doi: 10.1194/jlr.M005744. Epub 2010 Feb 17.

2.

Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.

Matsumoto S, Hara T, Mitsuyama K, Yamamoto M, Tsuruta O, Sata M, Scheller J, Rose-John S, Kado S, Takada T.

J Immunol. 2010 Feb 1;184(3):1543-51. doi: 10.4049/jimmunol.0801217. Epub 2009 Dec 30.

3.

Leptin signaling protects NK cells from apoptosis during development in mouse bone marrow.

Lo CK, Lam QL, Yang M, Ko KH, Sun L, Ma R, Wang S, Xu H, Tam S, Wu CY, Zheng BJ, Lu L.

Cell Mol Immunol. 2009 Oct;6(5):353-60. doi: 10.1038/cmi.2009.46.

4.

Protection against intestinal amebiasis by a recombinant vaccine is transferable by T cells and mediated by gamma interferon.

Guo X, Barroso L, Becker SM, Lyerly DM, Vedvick TS, Reed SG, Petri WA Jr, Houpt ER.

Infect Immun. 2009 Sep;77(9):3909-18. doi: 10.1128/IAI.00487-09. Epub 2009 Jun 29.

5.
6.

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer.

Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, Vallabhapurapu S, Scheller J, Rose-John S, Cheroutre H, Eckmann L, Karin M.

Cancer Cell. 2009 Feb 3;15(2):103-13. doi: 10.1016/j.ccr.2009.01.001. Erratum in: Cancer Cell. 2009 Mar 3;15(3):241.

7.

gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.

Bollrath J, Phesse TJ, von Burstin VA, Putoczki T, Bennecke M, Bateman T, Nebelsiek T, Lundgren-May T, Canli O, Schwitalla S, Matthews V, Schmid RM, Kirchner T, Arkan MC, Ernst M, Greten FR.

Cancer Cell. 2009 Feb 3;15(2):91-102. doi: 10.1016/j.ccr.2009.01.002.

8.

Persistence of Entamoeba histolytica infection in CBA mice owes to intestinal IL-4 production and inhibition of protective IFN-gamma.

Guo X, Stroup SE, Houpt ER.

Mucosal Immunol. 2008 Mar;1(2):139-46. doi: 10.1038/mi.2007.18. Epub 2008 Jan 9.

PMID:
19079171
9.

Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaB.

Edelblum KL, Washington MK, Koyama T, Robine S, Baccarini M, Polk DB.

Gastroenterology. 2008 Aug;135(2):539-51. doi: 10.1053/j.gastro.2008.04.025. Epub 2008 Apr 30.

10.

Leptin and the obesity receptor (OB-R) in the small intestine and colon: a colocalization study.

Hansen GH, Niels-Christiansen LL, Danielsen EM.

J Histochem Cytochem. 2008 Jul;56(7):677-85. doi: 10.1369/jhc.2008.950782. Epub 2008 Apr 14.

11.

Extracellular signal-regulated kinase activation by Neisseria gonorrhoeae downregulates epithelial cell proapoptotic proteins Bad and Bim.

Howie HL, Shiflett SL, So M.

Infect Immun. 2008 Jun;76(6):2715-21. doi: 10.1128/IAI.00153-08. Epub 2008 Apr 7.

12.

Leptin promotes cell survival and activates Jurkat T lymphocytes by stimulation of mitogen-activated protein kinase.

Fernández-Riejos P, Goberna R, Sánchez-Margalet V.

Clin Exp Immunol. 2008 Mar;151(3):505-18. doi: 10.1111/j.1365-2249.2007.03563.x.

13.

Mechanisms of leptin action and leptin resistance.

Myers MG, Cowley MA, Münzberg H.

Annu Rev Physiol. 2008;70:537-56. Review.

PMID:
17937601
14.

Leptin modulates the expression of secreted and membrane-associated mucins in colonic epithelial cells by targeting PKC, PI3K, and MAPK pathways.

El Homsi M, Ducroc R, Claustre J, Jourdan G, Gertler A, Estienne M, Bado A, Scoazec JY, Plaisancié P.

Am J Physiol Gastrointest Liver Physiol. 2007 Jul;293(1):G365-73. Epub 2007 May 10.

15.

Disruption of peripheral leptin signaling in mice results in hyperleptinemia without associated metabolic abnormalities.

Guo K, McMinn JE, Ludwig T, Yu YH, Yang G, Chen L, Loh D, Li C, Chua S Jr, Zhang Y.

Endocrinology. 2007 Aug;148(8):3987-97. Epub 2007 May 10.

PMID:
17495001
16.

Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function.

Björnholm M, Münzberg H, Leshan RL, Villanueva EC, Bates SH, Louis GW, Jones JC, Ishida-Takahashi R, Bjørbaek C, Myers MG Jr.

J Clin Invest. 2007 May;117(5):1354-60. Epub 2007 Apr 5.

17.

A key role of leptin in the control of regulatory T cell proliferation.

De Rosa V, Procaccini C, Calì G, Pirozzi G, Fontana S, Zappacosta S, La Cava A, Matarese G.

Immunity. 2007 Feb;26(2):241-55.

18.

Correlation of interferon-gamma production by peripheral blood mononuclear cells with childhood malnutrition and susceptibility to amebiasis.

Haque R, Mondal D, Shu J, Roy S, Kabir M, Davis AN, Duggal P, Petri WA Jr.

Am J Trop Med Hyg. 2007 Feb;76(2):340-4.

PMID:
17297046
19.
20.

Loss of SOCS3 gene expression converts STAT3 function from anti-apoptotic to pro-apoptotic.

Lu Y, Fukuyama S, Yoshida R, Kobayashi T, Saeki K, Shiraishi H, Yoshimura A, Takaesu G.

J Biol Chem. 2006 Dec 1;281(48):36683-90. Epub 2006 Oct 6.

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