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Items: 1 to 20 of 48


Pulsatile and sustained gonadotropin-releasing hormone (GnRH) receptor signaling: does the ERK signaling pathway decode GnRH pulse frequency?

Armstrong SP, Caunt CJ, Fowkes RC, Tsaneva-Atanasova K, McArdle CA.

J Biol Chem. 2010 Aug 6;285(32):24360-71. doi: 10.1074/jbc.M110.115964. Epub 2010 May 27.


ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motif-dependent signaling events.

Shin S, Dimitri CA, Yoon SO, Dowdle W, Blenis J.

Mol Cell. 2010 Apr 9;38(1):114-27. doi: 10.1016/j.molcel.2010.02.020.


Cell fate decisions are specified by the dynamic ERK interactome.

von Kriegsheim A, Baiocchi D, Birtwistle M, Sumpton D, Bienvenut W, Morrice N, Yamada K, Lamond A, Kalna G, Orton R, Gilbert D, Kolch W.

Nat Cell Biol. 2009 Dec;11(12):1458-64. doi: 10.1038/ncb1994. Epub 2009 Nov 22.


ERK nuclear translocation is dimerization-independent but controlled by the rate of phosphorylation.

Lidke DS, Huang F, Post JN, Rieger B, Wilsbacher J, Thomas JL, Pouysségur J, Jovin TM, Lenormand P.

J Biol Chem. 2010 Jan 29;285(5):3092-102. doi: 10.1074/jbc.M109.064972. Epub 2009 Nov 17.


A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal.

Catalanotti F, Reyes G, Jesenberger V, Galabova-Kovacs G, de Matos Simoes R, Carugo O, Baccarini M.

Nat Struct Mol Biol. 2009 Mar;16(3):294-303. doi: 10.1038/nsmb.1564. Epub 2009 Feb 15.


KSR1 modulates the sensitivity of mitogen-activated protein kinase pathway activation in T cells without altering fundamental system outputs.

Lin J, Harding A, Giurisato E, Shaw AS.

Mol Cell Biol. 2009 Apr;29(8):2082-91. doi: 10.1128/MCB.01634-08. Epub 2009 Feb 2.


A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy.

Lorenz K, Schmitt JP, Schmitteckert EM, Lohse MJ.

Nat Med. 2009 Jan;15(1):75-83. doi: 10.1038/nm.1893. Epub 2008 Dec 7.


Identification and characterization of a general nuclear translocation signal in signaling proteins.

Chuderland D, Konson A, Seger R.

Mol Cell. 2008 Sep 26;31(6):850-61. doi: 10.1016/j.molcel.2008.08.007. Epub 2008 Sep 4.


Spatiotemporal regulation of ERK2 by dual specificity phosphatases.

Caunt CJ, Armstrong SP, Rivers CA, Norman MR, McArdle CA.

J Biol Chem. 2008 Sep 26;283(39):26612-23. doi: 10.1074/jbc.M801500200. Epub 2008 Jul 23.


Calcium-mediated interactions regulate the subcellular localization of extracellular signal-regulated kinases.

Chuderland D, Marmor G, Shainskaya A, Seger R.

J Biol Chem. 2008 Apr 25;283(17):11176-88. doi: 10.1074/jbc.M709030200. Epub 2008 Feb 11.


Epidermal growth factor receptor and protein kinase C signaling to ERK2: spatiotemporal regulation of ERK2 by dual specificity phosphatases.

Caunt CJ, Rivers CA, Conway-Campbell BL, Norman MR, McArdle CA.

J Biol Chem. 2008 Mar 7;283(10):6241-52. doi: 10.1074/jbc.M706624200. Epub 2008 Jan 3.


Mutations in ERK2 binding sites affect nuclear entry.

Yazicioglu MN, Goad DL, Ranganathan A, Whitehurst AW, Goldsmith EJ, Cobb MH.

J Biol Chem. 2007 Sep 28;282(39):28759-67. Epub 2007 Jul 26.


Differential regulation and properties of MAPKs.

Raman M, Chen W, Cobb MH.

Oncogene. 2007 May 14;26(22):3100-12. Review.


Mxi2 promotes stimulus-independent ERK nuclear translocation.

Casar B, Sanz-Moreno V, Yazicioglu MN, Rodríguez J, Berciano MT, Lafarga M, Cobb MH, Crespo P.

EMBO J. 2007 Feb 7;26(3):635-46. Epub 2007 Jan 25.


Dynamic regulation of ERK2 nuclear translocation and mobility in living cells.

Costa M, Marchi M, Cardarelli F, Roy A, Beltram F, Maffei L, Ratto GM.

J Cell Sci. 2006 Dec 1;119(Pt 23):4952-63. Epub 2006 Nov 14.


Seven-transmembrane receptor signalling and ERK compartmentalization.

Caunt CJ, Finch AR, Sedgley KR, McArdle CA.

Trends Endocrinol Metab. 2006 Sep;17(7):276-83. Epub 2006 Aug 4. Review.


The nuclear localization of ERK2 occurs by mechanisms both independent of and dependent on energy.

Ranganathan A, Yazicioglu MN, Cobb MH.

J Biol Chem. 2006 Jun 9;281(23):15645-52. Epub 2006 Apr 4.


Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors: receptor-specific activation mechanisms and compartmentalization.

Caunt CJ, Finch AR, Sedgley KR, Oakley L, Luttrell LM, McArdle CA.

J Biol Chem. 2006 Feb 3;281(5):2701-10. Epub 2005 Nov 28.


Spatially separate docking sites on ERK2 regulate distinct signaling events in vivo.

Dimitri CA, Dowdle W, MacKeigan JP, Blenis J, Murphy LO.

Curr Biol. 2005 Jul 26;15(14):1319-24.


Graded mitogen-activated protein kinase activity precedes switch-like c-Fos induction in mammalian cells.

Mackeigan JP, Murphy LO, Dimitri CA, Blenis J.

Mol Cell Biol. 2005 Jun;25(11):4676-82.

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