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Items: 1 to 20 of 59


Full distance-resolved folding energy landscape of one single protein molecule.

Gebhardt JC, Bornschlögl T, Rief M.

Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2013-8. doi: 10.1073/pnas.0909854107. Epub 2010 Jan 19.


Unraveling infectious structures, strain variants and species barriers for the yeast prion [PSI+].

Tessier PM, Lindquist S.

Nat Struct Mol Biol. 2009 Jun;16(6):598-605. doi: 10.1038/nsmb.1617.


Globular tetramers of beta(2)-microglobulin assemble into elaborate amyloid fibrils.

White HE, Hodgkinson JL, Jahn TR, Cohen-Krausz S, Gosal WS, Müller S, Orlova EV, Radford SE, Saibil HR.

J Mol Biol. 2009 May 29;389(1):48-57. doi: 10.1016/j.jmb.2009.03.066. Epub 2009 Apr 5.


Branching in amyloid fibril growth.

Andersen CB, Yagi H, Manno M, Martorana V, Ban T, Christiansen G, Otzen DE, Goto Y, Rischel C.

Biophys J. 2009 Feb 18;96(4):1529-36. doi: 10.1016/j.bpj.2008.11.024.


Simulations of nucleation and elongation of amyloid fibrils.

Zhang J, Muthukumar M.

J Chem Phys. 2009 Jan 21;130(3):035102. doi: 10.1063/1.3050295.


Theory, analysis, and interpretation of single-molecule force spectroscopy experiments.

Dudko OK, Hummer G, Szabo A.

Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15755-60. doi: 10.1073/pnas.0806085105. Epub 2008 Oct 13.


Folding and unfolding single RNA molecules under tension.

Woodside MT, García-García C, Block SM.

Curr Opin Chem Biol. 2008 Dec;12(6):640-6. doi: 10.1016/j.cbpa.2008.08.011. Epub 2008 Sep 9. Review.


Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs.

Wang H, Duennwald ML, Roberts BE, Rozeboom LM, Zhang YL, Steele AD, Krishnan R, Su LJ, Griffin D, Mukhopadhyay S, Hennessy EJ, Weigele P, Blanchard BJ, King J, Deniz AA, Buchwald SL, Ingram VM, Lindquist S, Shorter J.

Proc Natl Acad Sci U S A. 2008 May 20;105(20):7159-64. doi: 10.1073/pnas.0801934105. Epub 2008 May 14.


Chaperone-dependent amyloid assembly protects cells from prion toxicity.

Douglas PM, Treusch S, Ren HY, Halfmann R, Duennwald ML, Lindquist S, Cyr DM.

Proc Natl Acad Sci U S A. 2008 May 20;105(20):7206-11. doi: 10.1073/pnas.0802593105. Epub 2008 May 14.


Single-molecule force spectroscopy reveals a stepwise unfolding of Caenorhabditis elegans giant protein kinase domains.

Greene DN, Garcia T, Sutton RB, Gernert KM, Benian GM, Oberhauser AF.

Biophys J. 2008 Aug;95(3):1360-70. doi: 10.1529/biophysj.108.130237. Epub 2008 Apr 4.


Constitutive modeling of the stress-strain behavior of F-actin filament networks.

Palmer JS, Boyce MC.

Acta Biomater. 2008 May;4(3):597-612. doi: 10.1016/j.actbio.2007.12.007. Epub 2008 Jan 8.


Direct observation of chaperone-induced changes in a protein folding pathway.

Bechtluft P, van Leeuwen RG, Tyreman M, Tomkiewicz D, Nouwen N, Tepper HL, Driessen AJ, Tans SJ.

Science. 2007 Nov 30;318(5855):1458-61.


How do chemical denaturants affect the mechanical folding and unfolding of proteins?

Cao Y, Li H.

J Mol Biol. 2008 Jan 4;375(1):316-24. Epub 2007 Oct 15.


Mechanical unbinding of abeta peptides from amyloid fibrils.

Raman EP, Takeda T, Barsegov V, Klimov DK.

J Mol Biol. 2007 Oct 26;373(3):785-800. Epub 2007 Aug 22.


The structural basis of yeast prion strain variants.

Toyama BH, Kelly MJ, Gross JD, Weissman JS.

Nature. 2007 Sep 13;449(7159):233-7. Epub 2007 Sep 2.


Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models.

Cheng IH, Scearce-Levie K, Legleiter J, Palop JJ, Gerstein H, Bien-Ly N, Puoliväli J, Lesné S, Ashe KH, Muchowski PJ, Mucke L.

J Biol Chem. 2007 Aug 17;282(33):23818-28. Epub 2007 Jun 4.


Prion recognition elements govern nucleation, strain specificity and species barriers.

Tessier PM, Lindquist S.

Nature. 2007 May 31;447(7144):556-61. Epub 2007 May 9.


Kinesin motor mechanics: binding, stepping, tracking, gating, and limping.

Block SM.

Biophys J. 2007 May 1;92(9):2986-95. Epub 2007 Feb 26. Review. No abstract available.


A three-stage kinetic model of amyloid fibrillation.

Lee CC, Nayak A, Sethuraman A, Belfort G, McRae GJ.

Biophys J. 2007 May 15;92(10):3448-58. Epub 2007 Feb 26.


Hsp104-dependent remodeling of prion complexes mediates protein-only inheritance.

Satpute-Krishnan P, Langseth SX, Serio TR.

PLoS Biol. 2007 Feb;5(2):e24.

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