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Items: 1 to 20 of 33


A highly accurate statistical approach for the prediction of transmembrane beta-barrels.

Freeman TC Jr, Wimley WC.

Bioinformatics. 2010 Aug 15;26(16):1965-74. doi: 10.1093/bioinformatics/btq308. Epub 2010 Jun 10.


Structure and hydration of membranes embedded with voltage-sensing domains.

Krepkiy D, Mihailescu M, Freites JA, Schow EV, Worcester DL, Gawrisch K, Tobias DJ, White SH, Swartz KJ.

Nature. 2009 Nov 26;462(7272):473-9. doi: 10.1038/nature08542.


MPEx: a tool for exploring membrane proteins.

Snider C, Jayasinghe S, Hristova K, White SH.

Protein Sci. 2009 Dec;18(12):2624-8. doi: 10.1002/pro.256.


Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity.

Rathinakumar R, Walkenhorst WF, Wimley WC.

J Am Chem Soc. 2009 Jun 10;131(22):7609-17. doi: 10.1021/ja8093247.


Biomolecular engineering by combinatorial design and high-throughput screening: small, soluble peptides that permeabilize membranes.

Rathinakumar R, Wimley WC.

J Am Chem Soc. 2008 Jul 30;130(30):9849-58. doi: 10.1021/ja8017863. Epub 2008 Jul 9.


Distribution of amino acids in a lipid bilayer from computer simulations.

MacCallum JL, Bennett WF, Tieleman DP.

Biophys J. 2008 May 1;94(9):3393-404. doi: 10.1529/biophysj.107.112805. Epub 2008 Jan 22.


Molecular code for transmembrane-helix recognition by the Sec61 translocon.

Hessa T, Meindl-Beinker NM, Bernsel A, Kim H, Sato Y, Lerch-Bader M, Nilsson I, White SH, von Heijne G.

Nature. 2007 Dec 13;450(7172):1026-30.


Is arginine charged in a membrane?

Li L, Vorobyov I, MacKerell AD Jr, Allen TW.

Biophys J. 2008 Jan 15;94(2):L11-3. Epub 2007 Nov 2.


Effect of sequence hydrophobicity and bilayer width upon the minimum length required for the formation of transmembrane helices in membranes.

Krishnakumar SS, London E.

J Mol Biol. 2007 Nov 30;374(3):671-87. Epub 2007 Sep 20. Erratum in: J Mol Biol. 2008 Dec 19;384(3):740-1.


Partitioning of amino acid side chains into lipid bilayers: results from computer simulations and comparison to experiment.

MacCallum JL, Bennett WF, Tieleman DP.

J Gen Physiol. 2007 May;129(5):371-7. Epub 2007 Apr 16. No abstract available.


On the thermodynamic stability of a charged arginine side chain in a transmembrane helix.

Dorairaj S, Allen TW.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):4943-8. Epub 2007 Mar 13.


A voltage-sensor water pore.

Freites JA, Tobias DJ, White SH.

Biophys J. 2006 Dec 1;91(11):L90-2. Epub 2006 Sep 29.


Interface connections of a transmembrane voltage sensor.

Freites JA, Tobias DJ, von Heijne G, White SH.

Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15059-64. Epub 2005 Oct 10.


Properties of integral membrane protein structures: derivation of an implicit membrane potential.

Ulmschneider MB, Sansom MS, Di Nola A.

Proteins. 2005 May 1;59(2):252-65.


Membrane insertion of a potassium-channel voltage sensor.

Hessa T, White SH, von Heijne G.

Science. 2005 Mar 4;307(5714):1427. Epub 2005 Jan 27. Erratum in: Science. 2005 Jun 17;308(5729):1743.


Recognition of transmembrane helices by the endoplasmic reticulum translocon.

Hessa T, Kim H, Bihlmaier K, Lundin C, Boekel J, Andersson H, Nilsson I, White SH, von Heijne G.

Nature. 2005 Jan 27;433(7024):377-81.


Multidimensional signatures in antimicrobial peptides.

Yount NY, Yeaman MR.

Proc Natl Acad Sci U S A. 2004 May 11;101(19):7363-8. Epub 2004 Apr 26.


The versatile beta-barrel membrane protein.

Wimley WC.

Curr Opin Struct Biol. 2003 Aug;13(4):404-11. Review.


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