Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 48


DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

Cejka P, Cannavo E, Polaczek P, Masuda-Sasa T, Pokharel S, Campbell JL, Kowalczykowski SC.

Nature. 2010 Sep 2;467(7311):112-6. doi: 10.1038/nature09355.


Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.

Niu H, Chung WH, Zhu Z, Kwon Y, Zhao W, Chi P, Prakash R, Seong C, Liu D, Lu L, Ira G, Sung P.

Nature. 2010 Sep 2;467(7311):108-11. doi: 10.1038/nature09318.


Defective resection at DNA double-strand breaks leads to de novo telomere formation and enhances gene targeting.

Chung WH, Zhu Z, Papusha A, Malkova A, Ira G.

PLoS Genet. 2010 May 13;6(5):e1000948. doi: 10.1371/journal.pgen.1000948.


Ctp1 and the MRN-complex are required for endonucleolytic Rec12 removal with release of a single class of oligonucleotides in fission yeast.

Rothenberg M, Kohli J, Ludin K.

PLoS Genet. 2009 Nov;5(11):e1000722. doi: 10.1371/journal.pgen.1000722. Epub 2009 Nov 13.


Meiotic DNA double-strand break repair requires two nucleases, MRN and Ctp1, to produce a single size class of Rec12 (Spo11)-oligonucleotide complexes.

Milman N, Higuchi E, Smith GR.

Mol Cell Biol. 2009 Nov;29(22):5998-6005. doi: 10.1128/MCB.01127-09. Epub 2009 Sep 14.


Interplay of Mre11 nuclease with Dna2 plus Sgs1 in Rad51-dependent recombinational repair.

Budd ME, Campbell JL.

PLoS One. 2009;4(1):e4267. doi: 10.1371/journal.pone.0004267. Epub 2009 Jan 23.


Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA.

Hartsuiker E, Neale MJ, Carr AM.

Mol Cell. 2009 Jan 16;33(1):117-23. doi: 10.1016/j.molcel.2008.11.021.


Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRN-dependent meiotic functions.

Hartsuiker E, Mizuno K, Molnar M, Kohli J, Ohta K, Carr AM.

Mol Cell Biol. 2009 Apr;29(7):1671-81. doi: 10.1128/MCB.01182-08. Epub 2009 Jan 12.


Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair.

Nimonkar AV, Ozsoy AZ, Genschel J, Modrich P, Kowalczykowski SC.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):16906-11. doi: 10.1073/pnas.0809380105. Epub 2008 Oct 29.


The P. furiosus mre11/rad50 complex promotes 5' strand resection at a DNA double-strand break.

Hopkins BB, Paull TT.

Cell. 2008 Oct 17;135(2):250-60. doi: 10.1016/j.cell.2008.09.054.


Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.

Buis J, Wu Y, Deng Y, Leddon J, Westfield G, Eckersdorff M, Sekiguchi JM, Chang S, Ferguson DO.

Cell. 2008 Oct 3;135(1):85-96. doi: 10.1016/j.cell.2008.08.015.


Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing.

Mimitou EP, Symington LS.

Nature. 2008 Oct 9;455(7214):770-4. doi: 10.1038/nature07312. Epub 2008 Sep 21.


Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends.

Zhu Z, Chung WH, Shim EY, Lee SE, Ira G.

Cell. 2008 Sep 19;134(6):981-94. doi: 10.1016/j.cell.2008.08.037.


Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations.

Lee K, Zhang Y, Lee SE.

Nature. 2008 Jul 24;454(7203):543-6. doi: 10.1038/nature07054.


Break dosage, cell cycle stage and DNA replication influence DNA double strand break response.

Zierhut C, Diffley JF.

EMBO J. 2008 Jul 9;27(13):1875-85. doi: 10.1038/emboj.2008.111. Epub 2008 May 29.


Differential regulation of the cellular response to DNA double-strand breaks in G1.

Barlow JH, Lisby M, Rothstein R.

Mol Cell. 2008 Apr 11;30(1):73-85. doi: 10.1016/j.molcel.2008.01.016.


Mechanism of eukaryotic homologous recombination.

San Filippo J, Sung P, Klein H.

Annu Rev Biochem. 2008;77:229-57. doi: 10.1146/annurev.biochem.77.061306.125255. Review.


Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex.

Lengsfeld BM, Rattray AJ, Bhaskara V, Ghirlando R, Paull TT.

Mol Cell. 2007 Nov 30;28(4):638-51.


Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes.

Bhaskara V, Dupré A, Lengsfeld B, Hopkins BB, Chan A, Lee JH, Zhang X, Gautier J, Zakian V, Paull TT.

Mol Cell. 2007 Mar 9;25(5):647-61.


DNA double-strand break repair: all's well that ends well.

Wyman C, Kanaar R.

Annu Rev Genet. 2006;40:363-83. Review.


Supplemental Content

Support Center