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Items: 1 to 20 of 35

1.

Macrophages, innate immunity and cancer: balance, tolerance, and diversity.

Mantovani A, Sica A.

Curr Opin Immunol. 2010 Apr;22(2):231-7. doi: 10.1016/j.coi.2010.01.009. Epub 2010 Feb 9. Review.

PMID:
20144856
2.

Src kinases as therapeutic targets for cancer.

Kim LC, Song L, Haura EB.

Nat Rev Clin Oncol. 2009 Oct;6(10):587-95. doi: 10.1038/nrclinonc.2009.129. Review.

PMID:
19787002
3.

Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation.

Bhavsar PJ, Vigorito E, Turner M, Ridley AJ.

Exp Cell Res. 2009 Nov 15;315(19):3345-58. doi: 10.1016/j.yexcr.2009.08.010. Epub 2009 Aug 26.

PMID:
19715691
4.

Functional plasticity of macrophages: in situ reprogramming of tumor-associated macrophages.

Stout RD, Watkins SK, Suttles J.

J Leukoc Biol. 2009 Nov;86(5):1105-9. doi: 10.1189/jlb.0209073. Epub 2009 Jul 15. Review.

5.

Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility.

Tomar A, Schlaepfer DD.

Curr Opin Cell Biol. 2009 Oct;21(5):676-83. doi: 10.1016/j.ceb.2009.05.006. Epub 2009 Jun 12. Review.

6.

Adhesion signaling - crosstalk between integrins, Src and Rho.

Huveneers S, Danen EH.

J Cell Sci. 2009 Apr 15;122(Pt 8):1059-69. doi: 10.1242/jcs.039446. Review.

7.

Rac activation and inactivation control plasticity of tumor cell movement.

Sanz-Moreno V, Gadea G, Ahn J, Paterson H, Marra P, Pinner S, Sahai E, Marshall CJ.

Cell. 2008 Oct 31;135(3):510-23. doi: 10.1016/j.cell.2008.09.043.

8.

Localized alpha4 integrin phosphorylation directs shear stress-induced endothelial cell alignment.

Goldfinger LE, Tzima E, Stockton R, Kiosses WB, Kinbara K, Tkachenko E, Gutierrez E, Groisman A, Nguyen P, Chien S, Ginsberg MH.

Circ Res. 2008 Jul 18;103(2):177-85. doi: 10.1161/CIRCRESAHA.108.176354. Epub 2008 Jun 26.

9.

Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.

Weis SM, Lim ST, Lutu-Fuga KM, Barnes LA, Chen XL, Göthert JR, Shen TL, Guan JL, Schlaepfer DD, Cheresh DA.

J Cell Biol. 2008 Apr 7;181(1):43-50. doi: 10.1083/jcb.200710038.

10.

FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts.

Iwanicki MP, Vomastek T, Tilghman RW, Martin KH, Banerjee J, Wedegaertner PB, Parsons JT.

J Cell Sci. 2008 Mar 15;121(Pt 6):895-905. doi: 10.1242/jcs.020941. Epub 2008 Feb 26.

11.

Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase.

Owen KA, Pixley FJ, Thomas KS, Vicente-Manzanares M, Ray BJ, Horwitz AF, Parsons JT, Beggs HE, Stanley ER, Bouton AH.

J Cell Biol. 2007 Dec 17;179(6):1275-87. Epub 2007 Dec 10.

12.

Distinct FAK-Src activation events promote alpha5beta1 and alpha4beta1 integrin-stimulated neuroblastoma cell motility.

Wu L, Bernard-Trifilo JA, Lim Y, Lim ST, Mitra SK, Uryu S, Chen M, Pallen CJ, Cheung NK, Mikolon D, Mielgo A, Stupack DG, Schlaepfer DD.

Oncogene. 2008 Feb 28;27(10):1439-48. Epub 2007 Sep 10.

13.

Blockade of colony stimulating factor-1 (CSF-I) leads to inhibition of DSS-induced colitis.

Marshall D, Cameron J, Lightwood D, Lawson AD.

Inflamm Bowel Dis. 2007 Feb;13(2):219-24.

PMID:
17206685
14.

New vistas on macrophage differentiation and activation.

Mantovani A, Sica A, Locati M.

Eur J Immunol. 2007 Jan;37(1):14-6. Review.

15.

New approaches to blockade of alpha4-integrins, proven therapeutic targets in chronic inflammation.

Kummer C, Ginsberg MH.

Biochem Pharmacol. 2006 Nov 30;72(11):1460-8. Epub 2006 Jul 25. Review.

PMID:
16870156
16.

FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling.

Ohta Y, Hartwig JH, Stossel TP.

Nat Cell Biol. 2006 Aug;8(8):803-14. Epub 2006 Jul 23.

PMID:
16862148
17.

Rac1 and Rac2 regulate macrophage morphology but are not essential for migration.

Wheeler AP, Wells CM, Smith SD, Vega FM, Henderson RB, Tybulewicz VL, Ridley AJ.

J Cell Sci. 2006 Jul 1;119(Pt 13):2749-57. Epub 2006 Jun 13.

18.

The mononuclear phagocyte system.

Hume DA.

Curr Opin Immunol. 2006 Feb;18(1):49-53. Epub 2005 Dec 9. Review.

PMID:
16338128
19.

Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation of c-Src.

Hsia DA, Lim ST, Bernard-Trifilo JA, Mitra SK, Tanaka S, den Hertog J, Streblow DN, Ilic D, Ginsberg MH, Schlaepfer DD.

Mol Cell Biol. 2005 Nov;25(21):9700-12.

20.

An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells.

Nishiya N, Kiosses WB, Han J, Ginsberg MH.

Nat Cell Biol. 2005 Apr;7(4):343-52. Epub 2005 Mar 27. Erratum in: Nat Cell Biol. 2005 May;7(5):531.

PMID:
15793570

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