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Modes of p53 regulation.

Kruse JP, Gu W.

Cell. 2009 May 15;137(4):609-22. doi: 10.1016/j.cell.2009.04.050. Review.


Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma.

Morrison BH, Haney R, Lamarre E, Drazba J, Prestwich GD, Lindner DJ.

Oncogene. 2009 Jun 25;28(25):2383-92. doi: 10.1038/onc.2009.113. Epub 2009 May 11.


Blinded by the Light: The Growing Complexity of p53.

Vousden KH, Prives C.

Cell. 2009 May 1;137(3):413-31. doi: 10.1016/j.cell.2009.04.037. Review.


Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis.

Bhandari R, Juluri KR, Resnick AC, Snyder SH.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2349-53. doi: 10.1073/pnas.0712227105. Epub 2008 Feb 11.


HSP90 regulates cell survival via inositol hexakisphosphate kinase-2.

Chakraborty A, Koldobskiy MA, Sixt KM, Juluri KR, Mustafa AK, Snowman AM, van Rossum DB, Patterson RL, Snyder SH.

Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1134-9. doi: 10.1073/pnas.0711168105. Epub 2008 Jan 14.


Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic beta cells.

Illies C, Gromada J, Fiume R, Leibiger B, Yu J, Juhl K, Yang SN, Barma DK, Falck JR, Saiardi A, Barker CJ, Berggren PO.

Science. 2007 Nov 23;318(5854):1299-302.


Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation.

Das S, Raj L, Zhao B, Kimura Y, Bernstein A, Aaronson SA, Lee SW.

Cell. 2007 Aug 24;130(4):624-37.


Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates.

Lee YS, Mulugu S, York JD, O'Shea EK.

Science. 2007 Apr 6;316(5821):109-12.


A conserved family of enzymes that phosphorylate inositol hexakisphosphate.

Mulugu S, Bai W, Fridy PC, Bastidas RJ, Otto JC, Dollins DE, Haystead TA, Ribeiro AA, York JD.

Science. 2007 Apr 6;316(5821):106-9.


The multiple battles fought by anti-apoptotic p21.

Jänicke RU, Sohn D, Essmann F, Schulze-Osthoff K.

Cell Cycle. 2007 Feb 15;6(4):407-13. Epub 2007 Feb 19.


The p53 family in nervous system development and disease.

Jacobs WB, Kaplan DR, Miller FD.

J Neurochem. 2006 Jun;97(6):1571-84. Review.


p53 in recombination and repair.

Gatz SA, Wiesmüller L.

Cell Death Differ. 2006 Jun;13(6):1003-16. Review.


p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease.

Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, Taya Y, Hayward SD, Moran TH, Montell C, Ross CA, Snyder SH, Sawa A.

Neuron. 2005 Jul 7;47(1):29-41.


Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases.

Saiardi A, Resnick AC, Snowman AM, Wendland B, Snyder SH.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):1911-4. Epub 2005 Jan 21.


Inositol diphosphate signaling regulates telomere length.

York SJ, Armbruster BN, Greenwell P, Petes TD, York JD.

J Biol Chem. 2005 Feb 11;280(6):4264-9. Epub 2004 Nov 23.


Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death.

Nagata E, Luo HR, Saiardi A, Bae BI, Suzuki N, Snyder SH.

J Biol Chem. 2005 Jan 14;280(2):1634-40. Epub 2004 Nov 8.


Puma is an essential mediator of p53-dependent and -independent apoptotic pathways.

Jeffers JR, Parganas E, Lee Y, Yang C, Wang J, Brennan J, MacLean KH, Han J, Chittenden T, Ihle JN, McKinnon PJ, Cleveland JL, Zambetti GP.

Cancer Cell. 2003 Oct;4(4):321-8.


p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa.

Villunger A, Michalak EM, Coultas L, Müllauer F, Böck G, Ausserlechner MJ, Adams JM, Strasser A.

Science. 2003 Nov 7;302(5647):1036-8. Epub 2003 Sep 18.

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