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Cell cycle-dependent accumulation of histone H3.3 and euchromatic histone modifications in pericentromeric heterochromatin in response to a decrease in DNA methylation levels.

Sugimura K, Fukushima Y, Ishida M, Ito S, Nakamura M, Mori Y, Okumura K.

Exp Cell Res. 2010 Oct 15;316(17):2731-46. doi: 10.1016/j.yexcr.2010.06.016. Epub 2010 Jun 25.


A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation.

Neumann H, Hancock SM, Buning R, Routh A, Chapman L, Somers J, Owen-Hughes T, van Noort J, Rhodes D, Chin JW.

Mol Cell. 2009 Oct 9;36(1):153-63. doi: 10.1016/j.molcel.2009.07.027.


Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.

Sun Y, Jiang X, Xu Y, Ayrapetov MK, Moreau LA, Whetstine JR, Price BD.

Nat Cell Biol. 2009 Nov;11(11):1376-82. doi: 10.1038/ncb1982. Epub 2009 Sep 27.


Exonuclease function of human Mre11 promotes deletional nonhomologous end joining.

Zhuang J, Jiang G, Willers H, Xia F.

J Biol Chem. 2009 Oct 30;284(44):30565-73. doi: 10.1074/jbc.M109.059444. Epub 2009 Sep 9.


Vorinostat enhances the radiosensitivity of a breast cancer brain metastatic cell line grown in vitro and as intracranial xenografts.

Baschnagel A, Russo A, Burgan WE, Carter D, Beam K, Palmieri D, Steeg PS, Tofilon P, Camphausen K.

Mol Cancer Ther. 2009 Jun;8(6):1589-95. doi: 10.1158/1535-7163.MCT-09-0038. Epub 2009 Jun 9.


Heterochromatin protein 1 is recruited to various types of DNA damage.

Luijsterburg MS, Dinant C, Lans H, Stap J, Wiernasz E, Lagerwerf S, Warmerdam DO, Lindh M, Brink MC, Dobrucki JW, Aten JA, Fousteri MI, Jansen G, Dantuma NP, Vermeulen W, Mullenders LH, Houtsmuller AB, Verschure PJ, van Driel R.

J Cell Biol. 2009 May 18;185(4):577-86. doi: 10.1083/jcb.200810035.


The impact of heterochromatin on DSB repair.

Goodarzi AA, Noon AT, Jeggo PA.

Biochem Soc Trans. 2009 Jun;37(Pt 3):569-76. doi: 10.1042/BST0370569.


Histone H3-K56 acetylation is important for genomic stability in mammals.

Yuan J, Pu M, Zhang Z, Lou Z.

Cell Cycle. 2009 Jun 1;8(11):1747-53. Epub 2009 Jun 3.


Histone deacetylase Rpd3 antagonizes Sir2-dependent silent chromatin propagation.

Zhou J, Zhou BO, Lenzmeier BA, Zhou JQ.

Nucleic Acids Res. 2009 Jun;37(11):3699-713. doi: 10.1093/nar/gkp233. Epub 2009 Apr 16.


Deletion 5q in myelodysplastic syndrome: a paradigm for the study of hemizygous deletions in cancer.

Ebert BL.

Leukemia. 2009 Jul;23(7):1252-6. doi: 10.1038/leu.2009.53. Epub 2009 Mar 26. Review.


Enhancement of cisplatin cytotoxicity by SAHA involves endoplasmic reticulum stress-mediated apoptosis in oral squamous cell carcinoma cells.

Suzuki M, Endo M, Shinohara F, Echigo S, Rikiishi H.

Cancer Chemother Pharmacol. 2009 Nov;64(6):1115-22. doi: 10.1007/s00280-009-0969-x. Epub 2009 Mar 11.


HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions.

Aucott R, Bullwinkel J, Yu Y, Shi W, Billur M, Brown JP, Menzel U, Kioussis D, Wang G, Reisert I, Weimer J, Pandita RK, Sharma GG, Pandita TK, Fundele R, Singh PB.

J Cell Biol. 2008 Nov 17;183(4):597-606. doi: 10.1083/jcb.200804041.


NCBI GEO: archive for high-throughput functional genomic data.

Barrett T, Troup DB, Wilhite SE, Ledoux P, Rudnev D, Evangelista C, Kim IF, Soboleva A, Tomashevsky M, Marshall KA, Phillippy KH, Sherman PM, Muertter RN, Edgar R.

Nucleic Acids Res. 2009 Jan;37(Database issue):D885-90. doi: 10.1093/nar/gkn764. Epub 2008 Oct 21.


p53 chromatin epigenetic domain organization and p53 transcription.

Su CH, Shann YJ, Hsu MT.

Mol Cell Biol. 2009 Jan;29(1):93-103. doi: 10.1128/MCB.00704-08. Epub 2008 Oct 20.


Abnormal expression of insulin-like growth factor-II and its dynamic quantitative analysis at different stages of hepatocellular carcinoma development.

Qiu LW, Yao DF, Zong L, Lu YY, Huang H, Wu W, Wu XH.

Hepatobiliary Pancreat Dis Int. 2008 Aug;7(4):406-11.


DNA damage detection and repair pathways--recent advances with inhibitors of checkpoint kinases in cancer therapy.

Ashwell S, Zabludoff S.

Clin Cancer Res. 2008 Jul 1;14(13):4032-7. doi: 10.1158/1078-0432.CCR-07-5138. Review.


Identification of SOX4 target genes using phylogenetic footprinting-based prediction from expression microarrays suggests that overexpression of SOX4 potentiates metastasis in hepatocellular carcinoma.

Liao YL, Sun YM, Chau GY, Chau YP, Lai TC, Wang JL, Horng JT, Hsiao M, Tsou AP.

Oncogene. 2008 Sep 18;27(42):5578-89. doi: 10.1038/onc.2008.168. Epub 2008 May 26.


MicroRNA-34 mediates AR-dependent p53-induced apoptosis in prostate cancer.

Rokhlin OW, Scheinker VS, Taghiyev AF, Bumcrot D, Glover RA, Cohen MB.

Cancer Biol Ther. 2008 Aug;7(8):1288-96. Epub 2008 Aug 13.


Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells.

Kondo Y, Shen L, Ahmed S, Boumber Y, Sekido Y, Haddad BR, Issa JP.

PLoS One. 2008 Apr 30;3(4):e2037. doi: 10.1371/journal.pone.0002037.


HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response.

Ayoub N, Jeyasekharan AD, Bernal JA, Venkitaraman AR.

Nature. 2008 May 29;453(7195):682-6. doi: 10.1038/nature06875. Epub 2008 Apr 27.


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