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Items: 1 to 20 of 46

1.

Glucagon-like peptide-1 increases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression.

Cornu M, Modi H, Kawamori D, Kulkarni RN, Joffraud M, Thorens B.

J Biol Chem. 2010 Apr 2;285(14):10538-45. doi: 10.1074/jbc.M109.091116. Epub 2010 Feb 9.

2.

Pancreatic beta-cell mass in European subjects with type 2 diabetes.

Rahier J, Guiot Y, Goebbels RM, Sempoux C, Henquin JC.

Diabetes Obes Metab. 2008 Nov;10 Suppl 4:32-42. doi: 10.1111/j.1463-1326.2008.00969.x.

PMID:
18834431
3.

An update on lipotoxic endoplasmic reticulum stress in pancreatic beta-cells.

Cnop M, Igoillo-Esteve M, Cunha DA, Ladrière L, Eizirik DL.

Biochem Soc Trans. 2008 Oct;36(Pt 5):909-15. doi: 10.1042/BST0360909. Review.

PMID:
18793160
4.

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

Cunha DA, Hekerman P, Ladrière L, Bazarra-Castro A, Ortis F, Wakeham MC, Moore F, Rasschaert J, Cardozo AK, Bellomo E, Overbergh L, Mathieu C, Lupi R, Hai T, Herchuelz A, Marchetti P, Rutter GA, Eizirik DL, Cnop M.

J Cell Sci. 2008 Jul 15;121(Pt 14):2308-18. doi: 10.1242/jcs.026062. Epub 2008 Jun 17.

5.

Fatty acids as modulators of the cellular production of reactive oxygen species.

Schönfeld P, Wojtczak L.

Free Radic Biol Med. 2008 Aug 1;45(3):231-41. doi: 10.1016/j.freeradbiomed.2008.04.029. Epub 2008 Apr 29. Review.

PMID:
18482593
6.

Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes.

Cnop M.

Biochem Soc Trans. 2008 Jun;36(Pt 3):348-52. doi: 10.1042/BST0360348. Review.

PMID:
18481955
7.

Oxidative stress: the vulnerable beta-cell.

Lenzen S.

Biochem Soc Trans. 2008 Jun;36(Pt 3):343-7. doi: 10.1042/BST0360343. Review.

PMID:
18481954
8.

Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells.

Lambertucci RH, Hirabara SM, Silveira Ldos R, Levada-Pires AC, Curi R, Pithon-Curi TC.

J Cell Physiol. 2008 Sep;216(3):796-804. doi: 10.1002/jcp.21463.

PMID:
18446788
9.

Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells.

Lai E, Bikopoulos G, Wheeler MB, Rozakis-Adcock M, Volchuk A.

Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E540-50. doi: 10.1152/ajpendo.00478.2007. Epub 2008 Jan 15.

10.

Peroxisome proliferator-activated receptor alpha-retinoid X receptor agonists induce beta-cell protection against palmitate toxicity.

Hellemans K, Kerckhofs K, Hannaert JC, Martens G, Van Veldhoven P, Pipeleers D.

FEBS J. 2007 Dec;274(23):6094-105. Epub 2007 Oct 26.

11.

Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line.

Morgan D, Oliveira-Emilio HR, Keane D, Hirata AE, Santos da Rocha M, Bordin S, Curi R, Newsholme P, Carpinelli AR.

Diabetologia. 2007 Feb;50(2):359-69. Epub 2006 Dec 7.

PMID:
17151863
12.

Life and death decisions of the pancreatic beta-cell: the role of fatty acids.

Newsholme P, Keane D, Welters HJ, Morgan NG.

Clin Sci (Lond). 2007 Jan;112(1):27-42. Review.

PMID:
17132138
13.

Biochemistry of mammalian peroxisomes revisited.

Wanders RJ, Waterham HR.

Annu Rev Biochem. 2006;75:295-332. Review.

PMID:
16756494
14.

Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells.

Azevedo-Martins AK, Monteiro AP, Lima CL, Lenzen S, Curi R.

Toxicol In Vitro. 2006 Oct;20(7):1106-13. Epub 2006 Feb 28.

PMID:
16644178
15.

Genetically encoded fluorescent indicator for intracellular hydrogen peroxide.

Belousov VV, Fradkov AF, Lukyanov KA, Staroverov DB, Shakhbazov KS, Terskikh AV, Lukyanov S.

Nat Methods. 2006 Apr;3(4):281-6.

PMID:
16554833
16.
17.
18.

A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes.

Kashyap S, Belfort R, Gastaldelli A, Pratipanawatr T, Berria R, Pratipanawatr W, Bajaj M, Mandarino L, DeFronzo R, Cusi K.

Diabetes. 2003 Oct;52(10):2461-74.

19.

Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death.

El-Assaad W, Buteau J, Peyot ML, Nolan C, Roduit R, Hardy S, Joly E, Dbaibo G, Rosenberg L, Prentki M.

Endocrinology. 2003 Sep;144(9):4154-63.

PMID:
12933690
20.

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes.

Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC.

Diabetes. 2003 Jan;52(1):102-10.

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