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Effects of PNPLA3 on liver fat and metabolic profile in Hispanic children and adolescents.

Goran MI, Walker R, Le KA, Mahurkar S, Vikman S, Davis JN, Spruijt-Metz D, Weigensberg MJ, Allayee H.

Diabetes. 2010 Dec;59(12):3127-30. doi: 10.2337/db10-0554. Epub 2010 Sep 17.


Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection.

Starley BQ, Calcagno CJ, Harrison SA.

Hepatology. 2010 May;51(5):1820-32. doi: 10.1002/hep.23594. Review.


Interventions for improving metabolic risk in overweight Latino youth.

Davis JN, Ventura EE, Shaibi GQ, Byrd-Williams CE, Alexander KE, Vanni AK, Meija MR, Weigensberg MJ, Spruijt-Metz D, Goran MI.

Int J Pediatr Obes. 2010 Oct;5(5):451-5. doi: 10.3109/17477161003770123. Review.


A feed-forward loop amplifies nutritional regulation of PNPLA3.

Huang Y, He S, Li JZ, Seo YK, Osborne TF, Cohen JC, Hobbs HH.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7892-7. doi: 10.1073/pnas.1003585107. Epub 2010 Apr 12.


Nonalcoholic fatty liver disease: pathology and pathogenesis.

Tiniakos DG, Vos MB, Brunt EM.

Annu Rev Pathol. 2010;5:145-71. doi: 10.1146/annurev-pathol-121808-102132. Review.


The expression level of non-alcoholic fatty liver disease-related gene PNPLA3 in hepatocytes is highly influenced by hepatic lipid status.

Hoekstra M, Li Z, Kruijt JK, Van Eck M, Van Berkel TJ, Kuiper J.

J Hepatol. 2010 Feb;52(2):244-51. doi: 10.1016/j.jhep.2009.11.004. Epub 2009 Nov 24.


Weight loss reduces liver fat and improves hepatic and skeletal muscle insulin sensitivity in obese adolescents.

Vitola BE, Deivanayagam S, Stein RI, Mohammed BS, Magkos F, Kirk EP, Klein S.

Obesity (Silver Spring). 2009 Sep;17(9):1744-8. doi: 10.1038/oby.2009.171. Epub 2009 Jun 4.


Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes.

Lê KA, Ith M, Kreis R, Faeh D, Bortolotti M, Tran C, Boesch C, Tappy L.

Am J Clin Nutr. 2009 Jun;89(6):1760-5. doi: 10.3945/ajcn.2008.27336. Epub 2009 Apr 29.


Randomized control trial to improve adiposity and insulin resistance in overweight Latino adolescents.

Davis JN, Kelly LA, Lane CJ, Ventura EE, Byrd-Williams CE, Alexandar KA, Azen SP, Chou CP, Spruijt-Metz D, Weigensberg MJ, Berhane K, Goran MI.

Obesity (Silver Spring). 2009 Aug;17(8):1542-8. doi: 10.1038/oby.2009.19. Epub 2009 Feb 26.


High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease.

Kantartzis K, Thamer C, Peter A, Machann J, Schick F, Schraml C, Königsrainer A, Königsrainer I, Kröber S, Niess A, Fritsche A, Häring HU, Stefan N.

Gut. 2009 Sep;58(9):1281-8. doi: 10.1136/gut.2008.151977. Epub 2008 Dec 11.


Underreporting of energy intake in Brazilian women varies according to dietary assessment: a cross-sectional study using doubly labeled water.

Scagliusi FB, Ferriolli E, Pfrimer K, Laureano C, Cunha CS, Gualano B, Lourenço BH, Lancha AH Jr.

J Am Diet Assoc. 2008 Dec;108(12):2031-40. doi: 10.1016/j.jada.2008.09.012.


Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.

Romeo S, Kozlitina J, Xing C, Pertsemlidis A, Cox D, Pennacchio LA, Boerwinkle E, Cohen JC, Hobbs HH.

Nat Genet. 2008 Dec;40(12):1461-5. doi: 10.1038/ng.257. Epub 2008 Sep 25.


Associations of dietary sugar and glycemic index with adiposity and insulin dynamics in overweight Latino youth.

Davis JN, Alexander KE, Ventura EE, Kelly LA, Lane CJ, Byrd-Williams CE, Toledo-Corral CM, Roberts CK, Spruijt-Metz D, Weigensberg MJ, Goran MI.

Am J Clin Nutr. 2007 Nov;86(5):1331-8.


Prevalence of fatty liver in children and adolescents.

Schwimmer JB, Deutsch R, Kahen T, Lavine JE, Stanley C, Behling C.

Pediatrics. 2006 Oct;118(4):1388-93.


Variation in the adiponutrin gene influences its expression and associates with obesity.

Johansson LE, Hoffstedt J, Parikh H, Carlsson E, Wabitsch M, Bondeson AG, Hedenbro J, Tornqvist H, Groop L, Ridderstråle M.

Diabetes. 2006 Mar;55(3):826-33.


The relation of sugar intake to beta cell function in overweight Latino children.

Davis JN, Ventura EE, Weigensberg MJ, Ball GD, Cruz ML, Shaibi GQ, Goran MI.

Am J Clin Nutr. 2005 Nov;82(5):1004-10.


Decreased beta-cell function in overweight Latino children with impaired fasting glucose.

Weigensberg MJ, Ball GD, Shaibi GQ, Cruz ML, Goran MI.

Diabetes Care. 2005 Oct;28(10):2519-24.


Effect of changes on body weight and lifestyle in nonalcoholic fatty liver disease.

Suzuki A, Lindor K, St Saver J, Lymp J, Mendes F, Muto A, Okada T, Angulo P.

J Hepatol. 2005 Dec;43(6):1060-6. Epub 2005 Jul 11.


Effect of fructose overfeeding and fish oil administration on hepatic de novo lipogenesis and insulin sensitivity in healthy men.

Faeh D, Minehira K, Schwarz JM, Periasamy R, Park S, Tappy L.

Diabetes. 2005 Jul;54(7):1907-13. Erratum in: Diabetes. 2006 Feb;55(2):563. Periasami, Raj [corrected to Periasamy, Raj]; Seongsu, Park [corrected to Park, Seongsu].


Secular trends in under-reporting in young people.

Rennie KL, Jebb SA, Wright A, Coward WA.

Br J Nutr. 2005 Feb;93(2):241-7.


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