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Items: 1 to 20 of 259

1.

Modulation of curcumin-induced Akt phosphorylation and apoptosis by PI3K inhibitor in MCF-7 cells.

Kizhakkayil J, Thayyullathil F, Chathoth S, Hago A, Patel M, Galadari S.

Biochem Biophys Res Commun. 2010 Apr 9;394(3):476-81. doi: 10.1016/j.bbrc.2010.01.132. Epub 2010 Feb 6.

PMID:
20138829
2.

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies.

Epstein J, Sanderson IR, Macdonald TT.

Br J Nutr. 2010 Jun;103(11):1545-57. doi: 10.1017/S0007114509993667. Epub 2010 Jan 26. Review.

PMID:
20100380
3.

Inhibitory effect of curcumin on IMP dehydrogenase, the target for anticancer and antiviral chemotherapy agents.

Dairaku I, Han Y, Yanaka N, Kato N.

Biosci Biotechnol Biochem. 2010;74(1):185-7. Epub 2010 Jan 7.

4.

Curcumin and its analogues: potential anticancer agents.

Agrawal DK, Mishra PK.

Med Res Rev. 2010 Sep;30(5):818-60. doi: 10.1002/med.20188. Review.

PMID:
20027668
5.

Insights into the inhibition of xanthine oxidase by curcumin.

Shen L, Ji HF.

Bioorg Med Chem Lett. 2009 Nov 1;19(21):5990-3. doi: 10.1016/j.bmcl.2009.09.076. Epub 2009 Sep 24.

PMID:
19800788
6.

Inhibitory effect of curcumin on motility of human oral squamous carcinoma YD-10B cells via suppression of ERK and NF-kappaB activations.

Shin HK, Kim J, Lee EJ, Kim SH.

Phytother Res. 2010 Apr;24(4):577-82. doi: 10.1002/ptr.2989.

PMID:
19777504
7.

Curcumin inhibits phorbol myristate acetate (PMA)-induced MCP-1 expression by inhibiting ERK and NF-kappaB transcriptional activity.

Lim JH, Kwon TK.

Food Chem Toxicol. 2010 Jan;48(1):47-52. doi: 10.1016/j.fct.2009.09.013. Epub 2009 Sep 18.

PMID:
19766691
8.

Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway.

Mun SH, Kim HS, Kim JW, Ko NY, Kim DK, Lee BY, Kim B, Won HS, Shin HS, Han JW, Lee HY, Kim YM, Choi WS.

J Pharmacol Sci. 2009 Sep;111(1):13-21.

9.

Curcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERT.

Lee JH, Chung IK.

Cancer Lett. 2010 Apr 1;290(1):76-86. doi: 10.1016/j.canlet.2009.08.026. Epub 2009 Sep 13.

PMID:
19751963
10.

Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo.

Anand P, Nair HB, Sung B, Kunnumakkara AB, Yadav VR, Tekmal RR, Aggarwal BB.

Biochem Pharmacol. 2010 Feb 1;79(3):330-8. doi: 10.1016/j.bcp.2009.09.003. Epub 2009 Sep 6. Retraction in: Biochem Pharmacol. 2016 Feb 15;102:143.

11.

Frequent alterations of the PI3K/AKT/mTOR pathways in hereditary nonpolyposis colorectal cancer.

Ekstrand AI, J├Ânsson M, Lindblom A, Borg A, Nilbert M.

Fam Cancer. 2010 Jun;9(2):125-9. doi: 10.1007/s10689-009-9293-1.

PMID:
19731079
12.

Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: a crucial role of AMPK and mTOR pathways.

Chiang PC, Lin SC, Pan SL, Kuo CH, Tsai IL, Kuo MT, Wen WC, Chen P, Guh JH.

Biochem Pharmacol. 2010 Jan 15;79(2):162-71. doi: 10.1016/j.bcp.2009.08.022. Epub 2009 Aug 31.

PMID:
19723512
13.

Regulatory effect of the AMPK-COX-2 signaling pathway in curcumin-induced apoptosis in HT-29 colon cancer cells.

Lee YK, Park SY, Kim YM, Park OJ.

Ann N Y Acad Sci. 2009 Aug;1171:489-94. doi: 10.1111/j.1749-6632.2009.04699.x.

PMID:
19723094
14.

Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling.

Johnson SM, Gulhati P, Arrieta I, Wang X, Uchida T, Gao T, Evers BM.

Anticancer Res. 2009 Aug;29(8):3185-90. Erratum in: Anticancer Res. 2009 Oct;29(10):4315.

15.

Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model.

Kunnumakkara AB, Diagaradjane P, Anand P, Harikumar KB, Deorukhkar A, Gelovani J, Guha S, Krishnan S, Aggarwal BB.

Int J Cancer. 2009 Nov 1;125(9):2187-97. doi: 10.1002/ijc.24593. Erratum in: Int J Cancer. 2010 Feb 1;126(3):799. Kuzhuvelil, Harikumar B [corrected to Harikumar, Kuzhuvelil B].

16.

Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of Wnt/beta-catenin signaling.

Prasad CP, Rath G, Mathur S, Bhatnagar D, Ralhan R.

Chem Biol Interact. 2009 Oct 7;181(2):263-71. doi: 10.1016/j.cbi.2009.06.012. Epub 2009 Jun 30.

PMID:
19573523
17.

Vascular cell adhesion molecule-1 expression in human intestinal microvascular endothelial cells is regulated by PI 3-kinase/Akt/MAPK/NF-kappaB: inhibitory role of curcumin.

Binion DG, Heidemann J, Li MS, Nelson VM, Otterson MF, Rafiee P.

Am J Physiol Gastrointest Liver Physiol. 2009 Aug;297(2):G259-68. doi: 10.1152/ajpgi.00087.2009. Epub 2009 Jun 11.

18.

Apoptosis in cancer: key molecular signaling pathways and therapy targets.

Burz C, Berindan-Neagoe I, Balacescu O, Irimie A.

Acta Oncol. 2009;48(6):811-21. doi: 10.1080/02841860902974175. Review.

PMID:
19513886
19.

Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF).

Lin SS, Lai KC, Hsu SC, Yang JS, Kuo CL, Lin JP, Ma YS, Wu CC, Chung JG.

Cancer Lett. 2009 Nov 28;285(2):127-33. doi: 10.1016/j.canlet.2009.04.037. Epub 2009 May 23.

PMID:
19477063
20.

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival.

Peterson TR, Laplante M, Thoreen CC, Sancak Y, Kang SA, Kuehl WM, Gray NS, Sabatini DM.

Cell. 2009 May 29;137(5):873-86. doi: 10.1016/j.cell.2009.03.046. Epub 2009 May 14.

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