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Items: 1 to 20 of 63

1.

Involvement of choline transporter-like proteins, CTL1 and CTL2, in glucocorticoid-induced acceleration of phosphatidylcholine synthesis via increased choline uptake.

Nakamura T, Fujiwara R, Ishiguro N, Oyabu M, Nakanishi T, Shirasaka Y, Maeda T, Tamai I.

Biol Pharm Bull. 2010;33(4):691-6.

2.

Heat shock proteins as targets in oncology.

Giménez Ortiz A, Montalar Salcedo J.

Clin Transl Oncol. 2010 Mar;12(3):166-73. doi: 10.1007/s12094-010-0486-8. Review.

PMID:
20231121
3.

Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy.

Ward CS, Venkatesh HS, Chaumeil MM, Brandes AH, Vancriekinge M, Dafni H, Sukumar S, Nelson SJ, Vigneron DB, Kurhanewicz J, James CD, Haas-Kogan DA, Ronen SM.

Cancer Res. 2010 Feb 15;70(4):1296-305. doi: 10.1158/0008-5472.CAN-09-2251. Epub 2010 Feb 9.

4.

Molecular and functional imaging of cancer.

Bhujwalla ZM.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:47-9. doi: 10.1109/IEMBS.2009.5335068.

PMID:
19965110
5.

Metabolic assessment of the action of targeted cancer therapeutics using magnetic resonance spectroscopy.

Beloueche-Babari M, Chung YL, Al-Saffar NM, Falck-Miniotis M, Leach MO.

Br J Cancer. 2010 Jan 5;102(1):1-7. doi: 10.1038/sj.bjc.6605457. Epub 2009 Nov 24. Review.

6.

Proton MRS detects metabolic changes in hormone sensitive and resistant human prostate cancer models CWR22 and CWR22r.

Le HC, Lupu M, Kotedia K, Rosen N, Solit D, Koutcher JA.

Magn Reson Med. 2009 Nov;62(5):1112-9. doi: 10.1002/mrm.22137.

7.

Hsp90 and co-chaperones twist the functions of diverse client proteins.

Zuehlke A, Johnson JL.

Biopolymers. 2010 Mar;93(3):211-7. doi: 10.1002/bip.21292. Review.

8.

Targeting PI3K signalling in cancer: opportunities, challenges and limitations.

Engelman JA.

Nat Rev Cancer. 2009 Aug;9(8):550-62. doi: 10.1038/nrc2664. Review.

PMID:
19629070
9.

Detection of choline transporter-like 1 protein CTL1 in neuroblastoma x glioma cells and in the CNS, and its role in choline uptake.

Machová E, O'Regan S, Newcombe J, Meunier FM, Prentice J, Dove R, Lisá V, Dolezal V.

J Neurochem. 2009 Aug;110(4):1297-309. doi: 10.1111/j.1471-4159.2009.06218.x. Epub 2009 Jun 10.

10.

Abnormalities in glucose uptake and metabolism in imatinib-resistant human BCR-ABL-positive cells.

Kominsky DJ, Klawitter J, Brown JL, Boros LG, Melo JV, Eckhardt SG, Serkova NJ.

Clin Cancer Res. 2009 May 15;15(10):3442-50. doi: 10.1158/1078-0432.CCR-08-3291. Epub 2009 Apr 28.

11.

The solute carrier 44A1 is a mitochondrial protein and mediates choline transport.

Michel V, Bakovic M.

FASEB J. 2009 Aug;23(8):2749-58. doi: 10.1096/fj.08-121491. Epub 2009 Apr 8.

PMID:
19357133
12.

Evaluation of the Hsp90 inhibitor NVP-AUY922 in multicellular tumour spheroids with respect to effects on growth and PET tracer uptake.

Monazzam A, Razifar P, Ide S, Rugaard Jensen M, Josephsson R, Blomqvist C, Langström B, Bergström M.

Nucl Med Biol. 2009 Apr;36(3):335-42. doi: 10.1016/j.nucmedbio.2008.12.009.

PMID:
19324279
13.

Heat shock protein 90 is important for Sp1 stability during mitosis.

Wang SA, Chuang JY, Yeh SH, Wang YT, Liu YW, Chang WC, Hung JJ.

J Mol Biol. 2009 Apr 17;387(5):1106-19. doi: 10.1016/j.jmb.2009.02.040. Epub 2009 Feb 23.

PMID:
19245816
14.

Heat shock protein 90 as a drug target: some like it hot.

Banerji U.

Clin Cancer Res. 2009 Jan 1;15(1):9-14. doi: 10.1158/1078-0432.CCR-08-0132. Review.

15.

Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer.

Song D, Chaerkady R, Tan AC, García-García E, Nalli A, Suárez-Gauthier A, López-Ríos F, Zhang XF, Solomon A, Tong J, Read M, Fritz C, Jimeno A, Pandey A, Hidalgo M.

Mol Cancer Ther. 2008 Oct;7(10):3275-84. doi: 10.1158/1535-7163.MCT-08-0508.

16.

Molecular and functional imaging of breast cancer.

Glunde K, Jacobs MA, Pathak AP, Artemov D, Bhujwalla ZM.

NMR Biomed. 2009 Jan;22(1):92-103. doi: 10.1002/nbm.1269. Review.

PMID:
18792419
17.

Fatty acid synthase inhibition results in a magnetic resonance-detectable drop in phosphocholine.

Ross J, Najjar AM, Sankaranarayanapillai M, Tong WP, Kaluarachchi K, Ronen SM.

Mol Cancer Ther. 2008 Aug;7(8):2556-65. doi: 10.1158/1535-7163.MCT-08-0015.

18.

Recent advances in breast MRI and MRS.

Sinha S, Sinha U.

NMR Biomed. 2009 Jan;22(1):3-16. doi: 10.1002/nbm.1270. Review.

PMID:
18654998
19.

HER-2 positive breast cancer: what else beyond trastuzumab-based therapy?

Widakowich C, Dinh P, de Azambuja E, Awada A, Piccart-Gebhart M.

Anticancer Agents Med Chem. 2008 Jun;8(5):488-96. Review.

PMID:
18537532
20.

1H MR spectroscopic imaging of phospholipase-mediated membrane lipid release in apoptotic rat glioma in vivo.

Liimatainen TJ, Erkkilä AT, Valonen P, Vidgren H, Lakso M, Wong G, Gröhn OH, Ylä-Herttuala S, Hakumäki JM.

Magn Reson Med. 2008 Jun;59(6):1232-8. doi: 10.1002/mrm.21607.

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