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Items: 1 to 20 of 44

1.

FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation.

Davis DB, Lavine JA, Suhonen JI, Krautkramer KA, Rabaglia ME, Sperger JM, Fernandez LA, Yandell BS, Keller MP, Wang IM, Schadt EE, Attie AD.

Mol Endocrinol. 2010 Sep;24(9):1822-34. doi: 10.1210/me.2010-0082.

2.

Unique arrangement of alpha- and beta-cells in human islets of Langerhans.

Bosco D, Armanet M, Morel P, Niclauss N, Sgroi A, Muller YD, Giovannoni L, Parnaud G, Berney T.

Diabetes. 2010 May;59(5):1202-10. doi: 10.2337/db09-1177.

3.

{beta}-Cell mass dynamics and islet cell plasticity in human type 2 diabetes.

Hanley SC, Austin E, Assouline-Thomas B, Kapeluto J, Blaichman J, Moosavi M, Petropavlovskaia M, Rosenberg L.

Endocrinology. 2010 Apr;151(4):1462-72. doi: 10.1210/en.2009-1277.

PMID:
20176718
4.

Blood glucose levels regulate pancreatic beta-cell proliferation during experimentally-induced and spontaneous autoimmune diabetes in mice.

Pechhold K, Koczwara K, Zhu X, Harrison VS, Walker G, Lee J, Harlan DM.

PLoS One. 2009;4(3):e4827. doi: 10.1371/journal.pone.0004827.

5.

Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

Assmann A, Ueki K, Winnay JN, Kadowaki T, Kulkarni RN.

Mol Cell Biol. 2009 Jun;29(11):3219-28. doi: 10.1128/MCB.01489-08.

6.

Minireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansion.

Sachdeva MM, Stoffers DA.

Mol Endocrinol. 2009 Jun;23(6):747-58. doi: 10.1210/me.2008-0400. Review.

7.

Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo.

Fiaschi-Taesch N, Bigatel TA, Sicari B, Takane KK, Salim F, Velazquez-Garcia S, Harb G, Selk K, Cozar-Castellano I, Stewart AF.

Diabetes. 2009 Apr;58(4):882-93. doi: 10.2337/db08-0631.

8.

Glycogen synthase kinase-3 and mammalian target of rapamycin pathways contribute to DNA synthesis, cell cycle progression, and proliferation in human islets.

Liu H, Remedi MS, Pappan KL, Kwon G, Rohatgi N, Marshall CA, McDaniel ML.

Diabetes. 2009 Mar;58(3):663-72. doi: 10.2337/db07-1208.

9.

Blood vessels of human islets of Langerhans are surrounded by a double basement membrane.

Virtanen I, Banerjee M, Palgi J, Korsgren O, Lukinius A, Thornell LE, Kikkawa Y, Sekiguchi K, Hukkanen M, Konttinen YT, Otonkoski T.

Diabetologia. 2008 Jul;51(7):1181-91. doi: 10.1007/s00125-008-0997-9.

PMID:
18438639
10.

Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans.

Meier JJ, Butler AE, Saisho Y, Monchamp T, Galasso R, Bhushan A, Rizza RA, Butler PC.

Diabetes. 2008 Jun;57(6):1584-94. doi: 10.2337/db07-1369.

11.

Enhanced beta-cell mass without increased proliferation following chronic mild glucose infusion.

Jetton TL, Everill B, Lausier J, Roskens V, Habibovic A, LaRock K, Gokin A, Peshavaria M, Leahy JL.

Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E679-87. doi: 10.1152/ajpendo.00569.2007.

12.

Glucolipotoxicity: fuel excess and beta-cell dysfunction.

Poitout V, Robertson RP.

Endocr Rev. 2008 May;29(3):351-66. Review.

13.

Proliferation of sorted human and rat beta cells.

Parnaud G, Bosco D, Berney T, Pattou F, Kerr-Conte J, Donath MY, Bruun C, Mandrup-Poulsen T, Billestrup N, Halban PA.

Diabetologia. 2008 Jan;51(1):91-100.

PMID:
17994216
14.

Partial pancreatectomy in adult humans does not provoke beta-cell regeneration.

Menge BA, Tannapfel A, Belyaev O, Drescher R, Müller C, Uhl W, Schmidt WE, Meier JJ.

Diabetes. 2008 Jan;57(1):142-9.

15.

Modestly increased beta cell apoptosis but no increased beta cell replication in recent-onset type 1 diabetic patients who died of diabetic ketoacidosis.

Butler AE, Galasso R, Meier JJ, Basu R, Rizza RA, Butler PC.

Diabetologia. 2007 Nov;50(11):2323-31.

PMID:
17805509
16.

Glucose infusion in mice: a new model to induce beta-cell replication.

Alonso LC, Yokoe T, Zhang P, Scott DK, Kim SK, O'Donnell CP, Garcia-Ocaña A.

Diabetes. 2007 Jul;56(7):1792-801.

17.

Aging correlates with decreased beta-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for Fas and pancreatic duodenal homeobox-1.

Maedler K, Schumann DM, Schulthess F, Oberholzer J, Bosco D, Berney T, Donath MY.

Diabetes. 2006 Sep;55(9):2455-62.

18.

Direct evidence of attempted beta cell regeneration in an 89-year-old patient with recent-onset type 1 diabetes.

Meier JJ, Lin JC, Butler AE, Galasso R, Martinez DS, Butler PC.

Diabetologia. 2006 Aug;49(8):1838-44.

PMID:
16802132
19.

The unique cytoarchitecture of human pancreatic islets has implications for islet cell function.

Cabrera O, Berman DM, Kenyon NS, Ricordi C, Berggren PO, Caicedo A.

Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2334-9.

20.

Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy.

Brissova M, Fowler MJ, Nicholson WE, Chu A, Hirshberg B, Harlan DM, Powers AC.

J Histochem Cytochem. 2005 Sep;53(9):1087-97.

PMID:
15923354
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