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The Respiratory Exchange Ratio is Associated with Fitness Indicators Both in Trained and Untrained Men: A Possible Application for People with Reduced Exercise Tolerance.

Ramos-Jiménez A, Hernández-Torres RP, Torres-Durán PV, Romero-Gonzalez J, Mascher D, Posadas-Romero C, Juárez-Oropeza MA.

Clin Med Circ Respirat Pulm Med. 2008 Feb 1;2:1-9.


Mitochondrial respiration protects against oxygen-associated DNA damage.

Sung HJ, Ma W, Wang PY, Hynes J, O'Riordan TC, Combs CA, McCoy JP Jr, Bunz F, Kang JG, Hwang PM.

Nat Commun. 2010 Apr 12;1:5. doi: 10.1038/ncomms1003.


Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function.

Hu W, Zhang C, Wu R, Sun Y, Levine A, Feng Z.

Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7455-60. doi: 10.1073/pnas.1001006107. Epub 2010 Apr 8.


Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species.

Suzuki S, Tanaka T, Poyurovsky MV, Nagano H, Mayama T, Ohkubo S, Lokshin M, Hosokawa H, Nakayama T, Suzuki Y, Sugano S, Sato E, Nagao T, Yokote K, Tatsuno I, Prives C.

Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7461-6. doi: 10.1073/pnas.1002459107. Epub 2010 Mar 29.


Tumor protein 53 mutations and inherited cancer: beyond Li-Fraumeni syndrome.

Palmero EI, Achatz MI, Ashton-Prolla P, Olivier M, Hainaut P.

Curr Opin Oncol. 2010 Jan;22(1):64-9. doi: 10.1097/CCO.0b013e328333bf00. Review.


Autophagy is required to maintain muscle mass.

Masiero E, Agatea L, Mammucari C, Blaauw B, Loro E, Komatsu M, Metzger D, Reggiani C, Schiaffino S, Sandri M.

Cell Metab. 2009 Dec;10(6):507-15. doi: 10.1016/j.cmet.2009.10.008.


Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, Rabinowitz JD, Cantley LC, Thompson CB, Vander Heiden MG, Su SM.

Nature. 2009 Dec 10;462(7274):739-44. doi: 10.1038/nature08617.


p53 ancestry: gazing through an evolutionary lens.

Lu WJ, Amatruda JF, Abrams JM.

Nat Rev Cancer. 2009 Oct;9(10):758-62. doi: 10.1038/nrc2732. Review.


p53 and metabolism.

Vousden KH, Ryan KM.

Nat Rev Cancer. 2009 Oct;9(10):691-700. doi: 10.1038/nrc2715. Epub 2009 Sep 17. Review.


Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53.

Wong TS, Rajagopalan S, Freund SM, Rutherford TJ, Andreeva A, Townsley FM, Petrovich M, Fersht AR.

Nucleic Acids Res. 2009 Nov;37(20):6765-83. doi: 10.1093/nar/gkp750. Epub 2009 Sep 15.


Modulation of intracellular ROS levels by TIGAR controls autophagy.

Bensaad K, Cheung EC, Vousden KH.

EMBO J. 2009 Oct 7;28(19):3015-26. doi: 10.1038/emboj.2009.242. Epub 2009 Aug 27.


Polo-like kinases mediate cell survival in mitochondrial dysfunction.

Matsumoto T, Wang PY, Ma W, Sung HJ, Matoba S, Hwang PM.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14542-6. doi: 10.1073/pnas.0904229106. Epub 2009 Aug 11.


p53 improves aerobic exercise capacity and augments skeletal muscle mitochondrial DNA content.

Park JY, Wang PY, Matsumoto T, Sung HJ, Ma W, Choi JW, Anderson SA, Leary SC, Balaban RS, Kang JG, Hwang PM.

Circ Res. 2009 Sep 25;105(7):705-12, 11 p following 712. doi: 10.1161/CIRCRESAHA.109.205310. Epub 2009 Aug 20.


Anticancer DNA intercalators cause p53-dependent mitochondrial DNA nucleoid re-modelling.

Ashley N, Poulton J.

Oncogene. 2009 Nov 5;28(44):3880-91. doi: 10.1038/onc.2009.242. Epub 2009 Aug 17.


Cardiorespiratory fitness, lifestyle factors and cancer risk and mortality in Finnish men.

Laukkanen JA, Pukkala E, Rauramaa R, Mäkikallio TH, Toriola AT, Kurl S.

Eur J Cancer. 2010 Jan;46(2):355-63. doi: 10.1016/j.ejca.2009.07.013. Epub 2009 Aug 13.


Effect of thioredoxin deletion and p53 cysteine replacement on human p53 activity in wild-type and thioredoxin reductase null yeast.

Stoner CS, Pearson GD, Koç A, Merwin JR, Lopez NI, Merrill GF.

Biochemistry. 2009 Sep 29;48(38):9156-69. doi: 10.1021/bi900757q.


Function and biogenesis of iron-sulphur proteins.

Lill R.

Nature. 2009 Aug 13;460(7257):831-8. doi: 10.1038/nature08301. Review.


A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase.

Mitra K, Wunder C, Roysam B, Lin G, Lippincott-Schwartz J.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):11960-5. doi: 10.1073/pnas.0904875106. Epub 2009 Jul 15.


Down-regulation of Bcl-2 enhances autophagy activation and cell death induced by mitochondrial dysfunction in rat striatum.

Zhang XD, Wang Y, Wu JC, Lin F, Han R, Han F, Fukunaga K, Qin ZH.

J Neurosci Res. 2009 Dec;87(16):3600-10. doi: 10.1002/jnr.22152.


p53 regulates mtDNA copy number and mitocheckpoint pathway.

Kulawiec M, Ayyasamy V, Singh KK.

J Carcinog. 2009;8:8. doi: 10.4103/1477-3163.50893.

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