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Items: 1 to 20 of 49

1.

The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway.

Yang P, An H, Liu X, Wen M, Zheng Y, Rui Y, Cao X.

Nat Immunol. 2010 Jun;11(6):487-94. doi: 10.1038/ni.1876. Epub 2010 May 9.

PMID:
20453844
2.

Targeting early infection to prevent HIV-1 mucosal transmission.

Haase AT.

Nature. 2010 Mar 11;464(7286):217-23. doi: 10.1038/nature08757. Review.

PMID:
20220840
3.

Intracellular DNA recognition.

Hornung V, Latz E.

Nat Rev Immunol. 2010 Feb;10(2):123-30. doi: 10.1038/nri2690. Review.

PMID:
20098460
4.

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses.

Yanai H, Ban T, Wang Z, Choi MK, Kawamura T, Negishi H, Nakasato M, Lu Y, Hangai S, Koshiba R, Savitsky D, Ronfani L, Akira S, Bianchi ME, Honda K, Tamura T, Kodama T, Taniguchi T.

Nature. 2009 Nov 5;462(7269):99-103. doi: 10.1038/nature08512.

PMID:
19890330
5.

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity.

Ishikawa H, Ma Z, Barber GN.

Nature. 2009 Oct 8;461(7265):788-92. doi: 10.1038/nature08476. Epub 2009 Sep 23.

6.

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway.

Chiu YH, Macmillan JB, Chen ZJ.

Cell. 2009 Aug 7;138(3):576-91. doi: 10.1016/j.cell.2009.06.015. Epub 2009 Jul 23.

7.

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.

Ablasser A, Bauernfeind F, Hartmann G, Latz E, Fitzgerald KA, Hornung V.

Nat Immunol. 2009 Oct;10(10):1065-72. doi: 10.1038/ni.1779. Epub 2009 Jul 16.

8.

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization.

Sun W, Li Y, Chen L, Chen H, You F, Zhou X, Zhou Y, Zhai Z, Chen D, Jiang Z.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8653-8. doi: 10.1073/pnas.0900850106. Epub 2009 May 11.

9.

Ubiquitin-regulated recruitment of IkappaB kinase epsilon to the MAVS interferon signaling adapter.

Paz S, Vilasco M, Arguello M, Sun Q, Lacoste J, Nguyen TL, Zhao T, Shestakova EA, Zaari S, Bibeau-Poirier A, Servant MJ, Lin R, Meurs EF, Hiscott J.

Mol Cell Biol. 2009 Jun;29(12):3401-12. doi: 10.1128/MCB.00880-08. Epub 2009 Apr 20.

10.

Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.

Schroder K, Muruve DA, Tschopp J.

Curr Biol. 2009 Mar 24;19(6):R262-5. doi: 10.1016/j.cub.2009.02.011.

11.

The SET complex acts as a barrier to autointegration of HIV-1.

Yan N, Cherepanov P, Daigle JE, Engelman A, Lieberman J.

PLoS Pathog. 2009 Mar;5(3):e1000327. doi: 10.1371/journal.ppat.1000327. Epub 2009 Mar 6.

12.

Nucleotide sequences and modifications that determine RIG-I/RNA binding and signaling activities.

Uzri D, Gehrke L.

J Virol. 2009 May;83(9):4174-84. doi: 10.1128/JVI.02449-08. Epub 2009 Feb 18.

13.

Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance.

El Gazzar M, Yoza BK, Chen X, Garcia BA, Young NL, McCall CE.

Mol Cell Biol. 2009 Apr;29(7):1959-71. doi: 10.1128/MCB.01862-08. Epub 2009 Jan 21.

14.

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation.

Zhong B, Yang Y, Li S, Wang YY, Li Y, Diao F, Lei C, He X, Zhang L, Tien P, Shu HB.

Immunity. 2008 Oct 17;29(4):538-50. doi: 10.1016/j.immuni.2008.09.003. Epub 2008 Sep 25.

15.

The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease.

Lehtinen DA, Harvey S, Mulcahy MJ, Hollis T, Perrino FW.

J Biol Chem. 2008 Nov 14;283(46):31649-56. doi: 10.1074/jbc.M806155200. Epub 2008 Sep 18.

16.

Trex1 prevents cell-intrinsic initiation of autoimmunity.

Stetson DB, Ko JS, Heidmann T, Medzhitov R.

Cell. 2008 Aug 22;134(4):587-98. doi: 10.1016/j.cell.2008.06.032.

17.

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling.

Ishikawa H, Barber GN.

Nature. 2008 Oct 2;455(7213):674-8. doi: 10.1038/nature07317. Epub 2008 Aug 24. Erratum in: Nature. 2008 Nov 13;456(7219):274.

18.

Identification of host proteins required for HIV infection through a functional genomic screen.

Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ.

Science. 2008 Feb 15;319(5865):921-6. doi: 10.1126/science.1152725. Epub 2008 Jan 10.

19.

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

Lee-Kirsch MA, Gong M, Chowdhury D, Senenko L, Engel K, Lee YA, de Silva U, Bailey SL, Witte T, Vyse TJ, Kere J, Pfeiffer C, Harvey S, Wong A, Koskenmies S, Hummel O, Rohde K, Schmidt RE, Dominiczak AF, Gahr M, Hollis T, Perrino FW, Lieberman J, Hübner N.

Nat Genet. 2007 Sep;39(9):1065-7. Epub 2007 Jul 29.

PMID:
17660818
20.

LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration.

Shun MC, Raghavendra NK, Vandegraaff N, Daigle JE, Hughes S, Kellam P, Cherepanov P, Engelman A.

Genes Dev. 2007 Jul 15;21(14):1767-78.

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