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Items: 1 to 20 of 60

1.

Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1.

Cui M, Tang X, Christian WV, Yoon Y, Tieu K.

J Biol Chem. 2010 Apr 9;285(15):11740-52. doi: 10.1074/jbc.M109.066662. Epub 2010 Feb 17.

2.

PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy.

Kawajiri S, Saiki S, Sato S, Sato F, Hatano T, Eguchi H, Hattori N.

FEBS Lett. 2010 Mar 19;584(6):1073-9. doi: 10.1016/j.febslet.2010.02.016. Epub 2010 Feb 12.

3.

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.

Narendra DP, Jin SM, Tanaka A, Suen DF, Gautier CA, Shen J, Cookson MR, Youle RJ.

PLoS Biol. 2010 Jan 26;8(1):e1000298. doi: 10.1371/journal.pbio.1000298.

4.

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.

Geisler S, Holmström KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ, Springer W.

Nat Cell Biol. 2010 Feb;12(2):119-31. doi: 10.1038/ncb2012. Epub 2010 Jan 24.

PMID:
20098416
5.

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.

Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RL, Kim J, May J, Tocilescu MA, Liu W, Ko HS, Magrané J, Moore DJ, Dawson VL, Grailhe R, Dawson TM, Li C, Tieu K, Przedborski S.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):378-83. doi: 10.1073/pnas.0911187107. Epub 2009 Dec 4.

6.

Mitochondrial DNA (mtDNA) biogenesis: visualization and duel incorporation of BrdU and EdU into newly synthesized mtDNA in vitro.

Lentz SI, Edwards JL, Backus C, McLean LL, Haines KM, Feldman EL.

J Histochem Cytochem. 2010 Feb;58(2):207-18. doi: 10.1369/jhc.2009.954701.

7.

Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation.

Lutz AK, Exner N, Fett ME, Schlehe JS, Kloos K, Lämmermann K, Brunner B, Kurz-Drexler A, Vogel F, Reichert AS, Bouman L, Vogt-Weisenhorn D, Wurst W, Tatzelt J, Haass C, Winklhofer KF.

J Biol Chem. 2009 Aug 21;284(34):22938-51. doi: 10.1074/jbc.M109.035774. Epub 2009 Jun 22.

8.

Frequency and selectivity of mitochondrial fusion are key to its quality maintenance function.

Mouli PK, Twig G, Shirihai OS.

Biophys J. 2009 May 6;96(9):3509-18. doi: 10.1016/j.bpj.2008.12.3959.

9.

Mitochondrial dynamics in Parkinson's disease.

Van Laar VS, Berman SB.

Exp Neurol. 2009 Aug;218(2):247-56. doi: 10.1016/j.expneurol.2009.03.019. Epub 2009 Mar 28. Review.

10.

Mitophagy.

Tolkovsky AM.

Biochim Biophys Acta. 2009 Sep;1793(9):1508-15. doi: 10.1016/j.bbamcr.2009.03.002. Epub 2009 Mar 13. Review.

11.

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission.

Dagda RK, Cherra SJ 3rd, Kulich SM, Tandon A, Park D, Chu CT.

J Biol Chem. 2009 May 15;284(20):13843-55. doi: 10.1074/jbc.M808515200. Epub 2009 Mar 10.

12.

Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons.

Berman SB, Chen YB, Qi B, McCaffery JM, Rucker EB 3rd, Goebbels S, Nave KA, Arnold BA, Jonas EA, Pineda FJ, Hardwick JM.

J Cell Biol. 2009 Mar 9;184(5):707-19. doi: 10.1083/jcb.200809060. Epub 2009 Mar 2.

13.

Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses.

Macaskill AF, Rinholm JE, Twelvetrees AE, Arancibia-Carcamo IL, Muir J, Fransson A, Aspenstrom P, Attwell D, Kittler JT.

Neuron. 2009 Feb 26;61(4):541-55. doi: 10.1016/j.neuron.2009.01.030.

14.

The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility.

Wang X, Schwarz TL.

Cell. 2009 Jan 9;136(1):163-74. doi: 10.1016/j.cell.2008.11.046.

15.

Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells.

Borland MK, Trimmer PA, Rubinstein JD, Keeney PM, Mohanakumar K, Liu L, Bennett JP Jr.

Mol Neurodegener. 2008 Dec 29;3:21. doi: 10.1186/1750-1326-3-21.

16.

The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.

Park J, Lee G, Chung J.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):518-23. doi: 10.1016/j.bbrc.2008.11.086. Epub 2008 Dec 3.

PMID:
19056353
17.

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.

Narendra D, Tanaka A, Suen DF, Youle RJ.

J Cell Biol. 2008 Dec 1;183(5):795-803. doi: 10.1083/jcb.200809125. Epub 2008 Nov 24.

18.

Low dose rotenone treatment causes selective transcriptional activation of cell death related pathways in dopaminergic neurons in vivo.

Meurers BH, Zhu C, Fernagut PO, Richter F, Hsia YC, Fleming SM, Oh M, Elashoff D, Dicarlo CD, Seaman RL, Chesselet MF.

Neurobiol Dis. 2009 Feb;33(2):182-92. doi: 10.1016/j.nbd.2008.10.001. Epub 2008 Oct 26.

19.

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria.

Cereghetti GM, Stangherlin A, Martins de Brito O, Chang CR, Blackstone C, Bernardi P, Scorrano L.

Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15803-8. doi: 10.1073/pnas.0808249105. Epub 2008 Oct 6.

20.

Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA.

Parone PA, Da Cruz S, Tondera D, Mattenberger Y, James DI, Maechler P, Barja F, Martinou JC.

PLoS One. 2008 Sep 22;3(9):e3257. doi: 10.1371/journal.pone.0003257.

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