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Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era.

Humbert M, Sitbon O, Chaouat A, Bertocchi M, Habib G, Gressin V, Yaïci A, Weitzenblum E, Cordier JF, Chabot F, Dromer C, Pison C, Reynaud-Gaubert M, Haloun A, Laurent M, Hachulla E, Cottin V, Degano B, Jaïs X, Montani D, Souza R, Simonneau G.

Circulation. 2010 Jul 13;122(2):156-63. doi: 10.1161/CIRCULATIONAHA.109.911818. Epub 2010 Jun 28.


Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target.

Archer SL, Marsboom G, Kim GH, Zhang HJ, Toth PT, Svensson EC, Dyck JR, Gomberg-Maitland M, Thébaud B, Husain AN, Cipriani N, Rehman J.

Circulation. 2010 Jun 22;121(24):2661-71. doi: 10.1161/CIRCULATIONAHA.109.916098. Epub 2010 Jun 7.


Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies.

Archer SL, Weir EK, Wilkins MR.

Circulation. 2010 May 11;121(18):2045-66. doi: 10.1161/CIRCULATIONAHA.108.847707. Review. No abstract available.


Targeting of drugs and nanoparticles to tumors.

Ruoslahti E, Bhatia SN, Sailor MJ.

J Cell Biol. 2010 Mar 22;188(6):759-68. doi: 10.1083/jcb.200910104. Epub 2010 Mar 15. Review.


Systematic review of trials using vasodilators in pulmonary arterial hypertension: why a new approach is needed.

Macchia A, Marchioli R, Tognoni G, Scarano M, Marfisi R, Tavazzi L, Rich S.

Am Heart J. 2010 Feb;159(2):245-57. doi: 10.1016/j.ahj.2009.11.028. Review.


Pulmonary hypertension in lung diseases: survey of beliefs and practice patterns.

Minai OA, Nathan SD, Hill NS, Badesch DB, Stoller JK.

Respir Med. 2010 May;104(5):741-8. doi: 10.1016/j.rmed.2009.12.015. Epub 2010 Jan 21.


Percent emphysema, airflow obstruction, and impaired left ventricular filling.

Barr RG, Bluemke DA, Ahmed FS, Carr JJ, Enright PL, Hoffman EA, Jiang R, Kawut SM, Kronmal RA, Lima JA, Shahar E, Smith LJ, Watson KE.

N Engl J Med. 2010 Jan 21;362(3):217-27. doi: 10.1056/NEJMoa0808836.


Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension.

Rajkumar R, Konishi K, Richards TJ, Ishizawar DC, Wiechert AC, Kaminski N, Ahmad F.

Am J Physiol Heart Circ Physiol. 2010 Apr;298(4):H1235-48. doi: 10.1152/ajpheart.00254.2009. Epub 2010 Jan 15.


Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation.

Zuckerbraun BS, Shiva S, Ifedigbo E, Mathier MA, Mollen KP, Rao J, Bauer PM, Choi JJ, Curtis E, Choi AM, Gladwin MT.

Circulation. 2010 Jan 5;121(1):98-109. doi: 10.1161/CIRCULATIONAHA.109.891077. Epub 2009 Dec 21.


Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells.

Waypa GB, Marks JD, Guzy R, Mungai PT, Schriewer J, Dokic D, Schumacker PT.

Circ Res. 2010 Feb 19;106(3):526-35. doi: 10.1161/CIRCRESAHA.109.206334. Epub 2009 Dec 17.


Nitrate and nitrite in biology, nutrition and therapeutics.

Lundberg JO, Gladwin MT, Ahluwalia A, Benjamin N, Bryan NS, Butler A, Cabrales P, Fago A, Feelisch M, Ford PC, Freeman BA, Frenneaux M, Friedman J, Kelm M, Kevil CG, Kim-Shapiro DB, Kozlov AV, Lancaster JR Jr, Lefer DJ, McColl K, McCurry K, Patel RP, Petersson J, Rassaf T, Reutov VP, Richter-Addo GB, Schechter A, Shiva S, Tsuchiya K, van Faassen EE, Webb AJ, Zuckerbraun BS, Zweier JL, Weitzberg E.

Nat Chem Biol. 2009 Dec;5(12):865-9. doi: 10.1038/nchembio.260.


Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure.

Bogaard HJ, Natarajan R, Henderson SC, Long CS, Kraskauskas D, Smithson L, Ockaili R, McCord JM, Voelkel NF.

Circulation. 2009 Nov 17;120(20):1951-60. doi: 10.1161/CIRCULATIONAHA.109.883843. Epub 2009 Nov 2.


The protective role of adiponectin in pulmonary vascular disease.

Hansmann G, Rabinovitch M.

Am J Physiol Lung Cell Mol Physiol. 2010 Jan;298(1):L1-2. doi: 10.1152/ajplung.00367.2009. Epub 2009 Oct 30. No abstract available.


The effects of vasodilators in pulmonary hypertension: pulmonary vascular or peripheral vascular?

Rich S.

Circ Heart Fail. 2009 Mar;2(2):145-50. doi: 10.1161/CIRCHEARTFAILURE.108.805374. Review. No abstract available.


Thinking small, but with big league consequences: procoagulant microparticles in the alveolar space.

Zimmerman GA.

Am J Physiol Lung Cell Mol Physiol. 2009 Dec;297(6):L1033-4. doi: 10.1152/ajplung.00335.2009. Epub 2009 Oct 2. No abstract available.


Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: state of the art and clinical and research implications.

Champion HC, Michelakis ED, Hassoun PM.

Circulation. 2009 Sep 15;120(11):992-1007. doi: 10.1161/CIRCULATIONAHA.106.674028. Review. No abstract available.


Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure.

Stenmark KR, Meyrick B, Galie N, Mooi WJ, McMurtry IF.

Am J Physiol Lung Cell Mol Physiol. 2009 Dec;297(6):L1013-32. doi: 10.1152/ajplung.00217.2009. Epub 2009 Sep 11. Review.


Deformation imaging describes right ventricular function better than longitudinal displacement of the tricuspid ring.

Giusca S, Dambrauskaite V, Scheurwegs C, D'hooge J, Claus P, Herbots L, Magro M, Rademakers F, Meyns B, Delcroix M, Voigt JU.

Heart. 2010 Feb;96(4):281-8. doi: 10.1136/hrt.2009.171728. Epub 2009 Aug 30.


Cardiovascular pharmacogenomics and individualized drug therapy.

Pereira NL, Weinshilboum RM.

Nat Rev Cardiol. 2009 Oct;6(10):632-8. doi: 10.1038/nrcardio.2009.154. Epub 2009 Aug 25. Review.


Storage lesion in banked blood due to hemolysis-dependent disruption of nitric oxide homeostasis.

Gladwin MT, Kim-Shapiro DB.

Curr Opin Hematol. 2009 Nov;16(6):515-23. doi: 10.1097/MOH.0b013e32833157f4. Review.


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