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Items: 1 to 20 of 65

1.

GPI anchoring facilitates propagation and spread of misfolded Sup35 aggregates in mammalian cells.

Speare JO, Offerdahl DK, Hasenkrug A, Carmody AB, Baron GS.

EMBO J. 2010 Feb 17;29(4):782-94. doi: 10.1038/emboj.2009.392. Epub 2010 Jan 7.

2.

Fibril fragmentation enhances amyloid cytotoxicity.

Xue WF, Hellewell AL, Gosal WS, Homans SW, Hewitt EW, Radford SE.

J Biol Chem. 2009 Dec 4;284(49):34272-82. doi: 10.1074/jbc.M109.049809. Epub 2009 Oct 6.

3.

Lipid rafts and clathrin cooperate in the internalization of PrP in epithelial FRT cells.

Sarnataro D, Caputo A, Casanova P, Puri C, Paladino S, Tivodar SS, Campana V, Tacchetti C, Zurzolo C.

PLoS One. 2009 Jun 8;4(6):e5829. doi: 10.1371/journal.pone.0005829.

4.

Pathologic prion protein infects cells by lipid-raft dependent macropinocytosis.

Wadia JS, Schaller M, Williamson RA, Dowdy SF.

PLoS One. 2008;3(10):e3314. doi: 10.1371/journal.pone.0003314. Epub 2008 Oct 2.

5.

Synthetic lipid vesicles recruit native-like aggregates and affect the aggregation process of the prion Ure2p: insights on vesicle permeabilization and charge selectivity.

Pieri L, Bucciantini M, Guasti P, Savistchenko J, Melki R, Stefani M.

Biophys J. 2009 Apr 22;96(8):3319-30. doi: 10.1016/j.bpj.2008.12.3958.

6.

Novel glutaredoxin activity of the yeast prion protein Ure2 reveals a native-like dimer within fibrils.

Zhang ZR, Perrett S.

J Biol Chem. 2009 May 22;284(21):14058-67. doi: 10.1074/jbc.M901189200. Epub 2009 Mar 25.

7.

The yeast Sup35NM domain propagates as a prion in mammalian cells.

Krammer C, Kryndushkin D, Suhre MH, Kremmer E, Hofmann A, Pfeifer A, Scheibel T, Wickner RB, Schätzl HM, Vorberg I.

Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):462-7. doi: 10.1073/pnas.0811571106. Epub 2008 Dec 29.

8.

"Restoration" of glutathione transferase activity by single-site mutation of the yeast prion protein Ure2.

Zhang ZR, Bai M, Wang XY, Zhou JM, Perrett S.

J Mol Biol. 2008 Dec 19;384(3):641-51. doi: 10.1016/j.jmb.2008.09.047. Epub 2008 Sep 27.

PMID:
18845158
9.

Species-specific anti-apoptotic activity of cellular prion protein in a mouse PrP-deficient neuronal cell line transfected with mouse, hamster, and bovine Prnp.

Wu G, Nakajima K, Takeyama N, Yukawa M, Taniuchi Y, Sakudo A, Onodera T.

Neurosci Lett. 2008 Nov 28;446(1):11-5. doi: 10.1016/j.neulet.2008.09.020. Epub 2008 Sep 16.

PMID:
18809465
10.

The involvement of cellular prion protein in the autophagy pathway in neuronal cells.

Oh JM, Shin HY, Park SJ, Kim BH, Choi JK, Choi EK, Carp RI, Kim YS.

Mol Cell Neurosci. 2008 Oct;39(2):238-47. doi: 10.1016/j.mcn.2008.07.003. Epub 2008 Jul 12.

PMID:
18674620
11.

p75(NTR) activation of NF-kappaB is involved in PrP106-126-induced apoptosis in mouse neuroblastoma cells.

Bai Y, Li Q, Yang J, Zhou X, Yin X, Zhao D.

Neurosci Res. 2008 Sep;62(1):9-14. doi: 10.1016/j.neures.2008.05.004. Epub 2008 May 23.

PMID:
18602709
12.

Focusing on clathrin-mediated endocytosis.

Rappoport JZ.

Biochem J. 2008 Jun 15;412(3):415-23. doi: 10.1042/BJ20080474. Review.

PMID:
18498251
13.

Differentiation increases the resistance of neuronal cells to amyloid toxicity.

Cecchi C, Pensalfini A, Liguri G, Baglioni S, Fiorillo C, Guadagna S, Zampagni M, Formigli L, Nosi D, Stefani M.

Neurochem Res. 2008 Dec;33(12):2516-31. doi: 10.1007/s11064-008-9627-7. Epub 2008 Feb 29.

PMID:
18307032
14.

Endocytosis: clathrin-mediated membrane budding.

Ungewickell EJ, Hinrichsen L.

Curr Opin Cell Biol. 2007 Aug;19(4):417-25. Epub 2007 Jul 13. Review.

PMID:
17631994
15.

Insights into prion strains and neurotoxicity.

Aguzzi A, Heikenwalder M, Polymenidou M.

Nat Rev Mol Cell Biol. 2007 Jul;8(7):552-61. Review.

PMID:
17585315
16.

Protein misfolding, functional amyloid, and human disease.

Chiti F, Dobson CM.

Annu Rev Biochem. 2006;75:333-66. Review.

PMID:
16756495
17.

The prion protein and lipid rafts.

Taylor DR, Hooper NM.

Mol Membr Biol. 2006 Jan-Feb;23(1):89-99. Review.

PMID:
16611584
18.

The yeast prion Ure2p native-like assemblies are toxic to mammalian cells regardless of their aggregation state.

Pieri L, Bucciantini M, Nosi D, Formigli L, Savistchenko J, Melki R, Stefani M.

J Biol Chem. 2006 Jun 2;281(22):15337-44. Epub 2006 Mar 29.

19.

Common mechanisms of amyloid oligomer pathogenesis in degenerative disease.

Glabe CG.

Neurobiol Aging. 2006 Apr;27(4):570-5. Epub 2006 Feb 14. Review.

PMID:
16481071
20.

Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates.

Cecchi C, Baglioni S, Fiorillo C, Pensalfini A, Liguri G, Nosi D, Rigacci S, Bucciantini M, Stefani M.

J Cell Sci. 2005 Aug 1;118(Pt 15):3459-70.

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