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Items: 1 to 20 of 58

1.

Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells.

Tompkins DH, Besnard V, Lange AW, Wert SE, Keiser AR, Smith AN, Lang R, Whitsett JA.

PLoS One. 2009 Dec 14;4(12):e8248. doi: 10.1371/journal.pone.0008248.

2.

Forkhead box M1 transcriptional factor is required for smooth muscle cells during embryonic development of blood vessels and esophagus.

Ustiyan V, Wang IC, Ren X, Zhang Y, Snyder J, Xu Y, Wert SE, Lessard JL, Kalin TV, Kalinichenko VV.

Dev Biol. 2009 Dec 15;336(2):266-79. doi: 10.1016/j.ydbio.2009.10.007. Epub 2009 Oct 14.

3.

SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production.

Chen G, Korfhagen TR, Xu Y, Kitzmiller J, Wert SE, Maeda Y, Gregorieff A, Clevers H, Whitsett JA.

J Clin Invest. 2009 Oct;119(10):2914-24. doi: 10.1172/JCI39731. Epub 2009 Sep 14.

4.

Deletion of Forkhead Box M1 transcription factor from respiratory epithelial cells inhibits pulmonary tumorigenesis.

Wang IC, Meliton L, Ren X, Zhang Y, Balli D, Snyder J, Whitsett JA, Kalinichenko VV, Kalin TV.

PLoS One. 2009 Aug 12;4(8):e6609. doi: 10.1371/journal.pone.0006609.

5.

Overexpression of hedgehog pathway molecules and FOXM1 in non-small cell lung carcinomas.

Gialmanidis IP, Bravou V, Amanetopoulou SG, Varakis J, Kourea H, Papadaki H.

Lung Cancer. 2009 Oct;66(1):64-74. doi: 10.1016/j.lungcan.2009.01.007. Epub 2009 Feb 6.

PMID:
19200615
6.

Forkhead box M1 expression in pulmonary squamous cell carcinoma: correlation with clinicopathologic features and its prognostic significance.

Yang DK, Son CH, Lee SK, Choi PJ, Lee KE, Roh MS.

Hum Pathol. 2009 Apr;40(4):464-70. doi: 10.1016/j.humpath.2008.10.001. Epub 2009 Jan 3.

PMID:
19121844
7.

Transcriptional up-regulation of FoxM1 in response to hypoxia is mediated by HIF-1.

Xia LM, Huang WJ, Wang B, Liu M, Zhang Q, Yan W, Zhu Q, Luo M, Zhou ZZ, Tian DA.

J Cell Biochem. 2009 Feb 1;106(2):247-56. doi: 10.1002/jcb.21996.

PMID:
19097132
8.

Forkhead Box m1 transcription factor is required for perinatal lung function.

Kalin TV, Wang IC, Meliton L, Zhang Y, Wert SE, Ren X, Snyder J, Bell SM, Graf L Jr, Whitsett JA, Kalinichenko VV.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19330-5. doi: 10.1073/pnas.0806748105. Epub 2008 Nov 25.

9.

C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia.

Blanco-Bose WE, Murphy MJ, Ehninger A, Offner S, Dubey C, Huang W, Moore DD, Trumpp A.

Hepatology. 2008 Oct;48(4):1302-11. doi: 10.1002/hep.22475.

PMID:
18798339
10.

Anaphase-promoting complex/cyclosome-CDH1-mediated proteolysis of the forkhead box M1 transcription factor is critical for regulated entry into S phase.

Park HJ, Costa RH, Lau LF, Tyner AL, Raychaudhuri P.

Mol Cell Biol. 2008 Sep;28(17):5162-71. doi: 10.1128/MCB.00387-08. Epub 2008 Jun 23.

11.

FoxM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness.

Wang IC, Chen YJ, Hughes DE, Ackerson T, Major ML, Kalinichenko VV, Costa RH, Raychaudhuri P, Tyner AL, Lau LF.

J Biol Chem. 2008 Jul 25;283(30):20770-8. doi: 10.1074/jbc.M709892200. Epub 2008 Jun 4.

12.

FoxM1-driven cell division is required for neuronal differentiation in early Xenopus embryos.

Ueno H, Nakajo N, Watanabe M, Isoda M, Sagata N.

Development. 2008 Jun;135(11):2023-30. doi: 10.1242/dev.019893.

13.

Transgenic expression of the forkhead box M1 transcription factor induces formation of lung tumors.

Wang IC, Meliton L, Tretiakova M, Costa RH, Kalinichenko VV, Kalin TV.

Oncogene. 2008 Jul 10;27(30):4137-49. doi: 10.1038/onc.2008.60. Epub 2008 Mar 17.

PMID:
18345025
14.

Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain.

Laoukili J, Alvarez M, Meijer LA, Stahl M, Mohammed S, Kleij L, Heck AJ, Medema RH.

Mol Cell Biol. 2008 May;28(9):3076-87. doi: 10.1128/MCB.01710-07. Epub 2008 Feb 19.

15.

R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis.

Bell SM, Schreiner CM, Wert SE, Mucenski ML, Scott WJ, Whitsett JA.

Development. 2008 Mar;135(6):1049-58. doi: 10.1242/dev.013359. Epub 2008 Feb 6.

16.

Conditional deletion of Pten causes bronchiolar hyperplasia.

Davé V, Wert SE, Tanner T, Thitoff AR, Loudy DE, Whitsett JA.

Am J Respir Cell Mol Biol. 2008 Mar;38(3):337-45. Epub 2007 Oct 5.

17.

Forkhead transcription factor FoxM1 regulates mitotic entry and prevents spindle defects in cerebellar granule neuron precursors.

Schüller U, Zhao Q, Godinho SA, Heine VM, Medema RH, Pellman D, Rowitch DH.

Mol Cell Biol. 2007 Dec;27(23):8259-70. Epub 2007 Sep 24.

18.

An N-terminal inhibitory domain modulates activity of FoxM1 during cell cycle.

Park HJ, Wang Z, Costa RH, Tyner A, Lau LF, Raychaudhuri P.

Oncogene. 2008 Mar 13;27(12):1696-704. Epub 2007 Sep 24.

19.

The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer.

Yoshida Y, Wang IC, Yoder HM, Davidson NO, Costa RH.

Gastroenterology. 2007 Apr;132(4):1420-31. Epub 2007 Jan 25.

PMID:
17408638
20.

Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis.

Shaw AT, Meissner A, Dowdle JA, Crowley D, Magendantz M, Ouyang C, Parisi T, Rajagopal J, Blank LJ, Bronson RT, Stone JR, Tuveson DA, Jaenisch R, Jacks T.

Genes Dev. 2007 Mar 15;21(6):694-707. Erratum in: Genes Dev. 2008 Jan 15;22(2):277.

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