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Pharmacologic inhibition of phospholipid transfer protein activity reduces apolipoprotein-B secretion from hepatocytes.

Luo Y, Shelly L, Sand T, Reidich B, Chang G, Macdougall M, Peakman MC, Jiang XC.

J Pharmacol Exp Ther. 2010 Mar;332(3):1100-6. doi: 10.1124/jpet.109.161232. Epub 2009 Nov 20.


Plasma phospholipid transfer activity is essential for increased atherogenesis in PLTP transgenic mice: a mutation-inactivation study.

Samyn H, Moerland M, van Gent T, van Haperen R, Metso J, Grosveld F, Jauhiainen M, van Tol A, de Crom R.

J Lipid Res. 2008 Dec;49(12):2504-12. doi: 10.1194/jlr.M800080-JLR200. Epub 2008 Aug 18.


Elevated expression of phospholipid transfer protein in bone marrow derived cells causes atherosclerosis.

van Haperen R, Samyn H, Moerland M, van Gent T, Peeters M, Grosveld F, van Tol A, de Crom R.

PLoS One. 2008 May 28;3(5):e2255. doi: 10.1371/journal.pone.0002255.


Elevated plasma phospholipid transfer protein activity is a determinant of carotid intima-media thickness in type 2 diabetes mellitus.

de Vries R, Dallinga-Thie GM, Smit AJ, Wolffenbuttel BH, van Tol A, Dullaart RP.

Diabetologia. 2006 Feb;49(2):398-404. Epub 2005 Dec 23.


Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein.

Rava P, Athar H, Johnson C, Hussain MM.

J Lipid Res. 2005 Aug;46(8):1779-85. Epub 2005 May 16.


A simple, rapid, and sensitive fluorescence assay for microsomal triglyceride transfer protein.

Athar H, Iqbal J, Jiang XC, Hussain MM.

J Lipid Res. 2004 Apr;45(4):764-72. Epub 2004 Feb 1.


Phospholipid transfer protein and atherosclerosis.

Tall AR, Lalanne F.

Arterioscler Thromb Vasc Biol. 2003 Sep 1;23(9):1484-5. Review. No abstract available.


High plasma phospholipid transfer protein levels as a risk factor for coronary artery disease.

Schlitt A, Bickel C, Thumma P, Blankenberg S, Rupprecht HJ, Meyer J, Jiang XC.

Arterioscler Thromb Vasc Biol. 2003 Oct 1;23(10):1857-62. Epub 2003 Aug 28.


Increased atherosclerotic lesions in apoE mice with plasma phospholipid transfer protein overexpression.

Yang XP, Yan D, Qiao C, Liu RJ, Chen JG, Li J, Schneider M, Lagrost L, Xiao X, Jiang XC.

Arterioscler Thromb Vasc Biol. 2003 Sep 1;23(9):1601-7. Epub 2003 Jul 10.


CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans.

Chandler CE, Wilder DE, Pettini JL, Savoy YE, Petras SF, Chang G, Vincent J, Harwood HJ Jr.

J Lipid Res. 2003 Oct;44(10):1887-901. Epub 2003 Jul 1.


Microsomal triglyceride transfer protein: a multifunctional protein.

Hussain MM, Iqbal J, Anwar K, Rava P, Dai K.

Front Biosci. 2003 May 1;8:s500-6. Review.


Increased risk of atherosclerosis by elevated plasma levels of phospholipid transfer protein.

van Haperen R, van Tol A, van Gent T, Scheek L, Visser P, van der Kamp A, Grosveld F, de Crom R.

J Biol Chem. 2002 Dec 13;277(50):48938-43. Epub 2002 Oct 7.


Apolipoprotein B secretion and atherosclerosis are decreased in mice with phospholipid-transfer protein deficiency.

Jiang XC, Qin S, Qiao C, Kawano K, Lin M, Skold A, Xiao X, Tall AR.

Nat Med. 2001 Jul;7(7):847-52. Erratum in: Nat Med 2001 Aug;7(8):973.


A mechanism of membrane neutral lipid acquisition by the microsomal triglyceride transfer protein.

Read J, Anderson TA, Ritchie PJ, Vanloo B, Amey J, Levitt D, Rosseneu M, Scott J, Shoulders CC.

J Biol Chem. 2000 Sep 29;275(39):30372-7.


Chylomicron-sized lipid particles are formed in the setting of apolipoprotein B deficiency.

Hamilton RL, Wong JS, Cham CM, Nielsen LB, Young SG.

J Lipid Res. 1998 Aug;39(8):1543-57.


The contribution of lipids and lipid metabolism to cellular functions of the Golgi complex.

Fang M, Rivas MP, Bankaitis VA.

Biochim Biophys Acta. 1998 Aug 14;1404(1-2):85-100. Review.


Evidence that microsomal triglyceride transfer protein is limiting in the production of apolipoprotein B-containing lipoproteins in hepatic cells.

Jamil H, Chu CH, Dickson JK Jr, Chen Y, Yan M, Biller SA, Gregg RE, Wetterau JR, Gordon DA.

J Lipid Res. 1998 Jul;39(7):1448-54.


An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells.

Jamil H, Gordon DA, Eustice DC, Brooks CM, Dickson JK Jr, Chen Y, Ricci B, Chu CH, Harrity TW, Ciosek CP Jr, Biller SA, Gregg RE, Wetterau JR.

Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11991-5.

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