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Items: 1 to 20 of 48


Fine-scale variation and genetic determinants of alternative splicing across individuals.

Coulombe-Huntington J, Lam KC, Dias C, Majewski J.

PLoS Genet. 2009 Dec;5(12):e1000766. doi: 10.1371/journal.pgen.1000766. Epub 2009 Dec 11.


The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.

Krentz AD, Murphy MW, Kim S, Cook MS, Capel B, Zhu R, Matin A, Sarver AL, Parker KL, Griswold MD, Looijenga LH, Bardwell VJ, Zarkower D.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22323-8. doi: 10.1073/pnas.0905431106. Epub 2009 Dec 10.


Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.

Kanetsky PA, Mitra N, Vardhanabhuti S, Li M, Vaughn DJ, Letrero R, Ciosek SL, Doody DR, Smith LM, Weaver J, Albano A, Chen C, Starr JR, Rader DJ, Godwin AK, Reilly MP, Hakonarson H, Schwartz SM, Nathanson KL.

Nat Genet. 2009 Jul;41(7):811-5. doi: 10.1038/ng.393. Epub 2009 May 31.


A genome-wide association study of testicular germ cell tumor.

Rapley EA, Turnbull C, Al Olama AA, Dermitzakis ET, Linger R, Huddart RA, Renwick A, Hughes D, Hines S, Seal S, Morrison J, Nsengimana J, Deloukas P; UK Testicular Cancer Collaboration, Rahman N, Bishop DT, Easton DF, Stratton MR.

Nat Genet. 2009 Jul;41(7):807-10. doi: 10.1038/ng.394. Epub 2009 May 31.


BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1(Ter/Ter) mice.

Cook MS, Coveney D, Batchvarov I, Nadeau JH, Capel B.

Dev Biol. 2009 Apr 15;328(2):377-83. doi: 10.1016/j.ydbio.2009.01.041. Epub 2009 Feb 6.


Deletion of eIF2beta suppresses testicular cancer incidence and causes recessive lethality in agouti-yellow mice.

Heaney JD, Michelson MV, Youngren KK, Lam MY, Nadeau JH.

Hum Mol Genet. 2009 Apr 15;18(8):1395-404. doi: 10.1093/hmg/ddp045. Epub 2009 Jan 23.


The emerging role of splicing factors in cancer.

Grosso AR, Martins S, Carmo-Fonseca M.

EMBO Rep. 2008 Nov;9(11):1087-93. doi: 10.1038/embor.2008.189. Epub 2008 Oct 10.


Loss of the transmembrane but not the soluble kit ligand isoform increases testicular germ cell tumor susceptibility in mice.

Heaney JD, Lam MY, Michelson MV, Nadeau JH.

Cancer Res. 2008 Jul 1;68(13):5193-7. doi: 10.1158/0008-5472.CAN-08-0779.


Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells.

Dejosez M, Krumenacker JS, Zitur LJ, Passeri M, Chu LF, Songyang Z, Thomson JA, Zwaka TP.

Cell. 2008 Jun 27;133(7):1162-74. doi: 10.1016/j.cell.2008.05.047. Erratum in: Cell. 2008 Aug 22;134(4):692.


Expression of splicing variants of the inhibitor of apoptosis livin in testicular germ cell tumors.

Kempkensteffen C, Hinz S, Krause H, Jager T, Köllermann J, Weikert S, Christoph F, Schostak M, Miller K, Schrader M.

Tumour Biol. 2008;29(2):76-82. doi: 10.1159/000135687. Epub 2008 Jun 2.


Entropy measures quantify global splicing disorders in cancer.

Ritchie W, Granjeaud S, Puthier D, Gautheret D.

PLoS Comput Biol. 2008 Mar 14;4(3):e1000011. doi: 10.1371/journal.pcbi.1000011.


Insights into the connection between cancer and alternative splicing.

Kim E, Goren A, Ast G.

Trends Genet. 2008 Jan;24(1):7-10. Epub 2007 Dec 3.


Increased susceptibility of Sf1(+/-) mice to azoxymethane-induced colon tumorigenesis.

Shitashige M, Satow R, Honda K, Ono M, Hirohashi S, Yamada T.

Cancer Sci. 2007 Dec;98(12):1862-7. Epub 2007 Sep 26.


Genome-wide detection of testis- and testicular cancer-specific alternative splicing.

He C, Zuo Z, Chen H, Zhang L, Zhou F, Cheng H, Zhou R.

Carcinogenesis. 2007 Dec;28(12):2484-90. Epub 2007 Aug 27.


Testicular germ cell tumor susceptibility genes from the consomic 129.MOLF-Chr19 mouse strain.

Zhu R, Ji Y, Xiao L, Matin A.

Mamm Genome. 2007 Aug;18(8):584-95. Epub 2007 Aug 2.


Involvement of splicing factor-1 in beta-catenin/T-cell factor-4-mediated gene transactivation and pre-mRNA splicing.

Shitashige M, Naishiro Y, Idogawa M, Honda K, Ono M, Hirohashi S, Yamada T.

Gastroenterology. 2007 Mar;132(3):1039-54. Epub 2007 Jan 5.


A physical analysis of the Y chromosome shows no additional deletions, other than Gr/Gr, associated with testicular germ cell tumour.

Linger R, Dudakia D, Huddart R, Easton D, Bishop DT, Stratton MR, Rapley EA.

Br J Cancer. 2007 Jan 29;96(2):357-61. Epub 2007 Jan 9.


The connection between splicing and cancer.

Srebrow A, Kornblihtt AR.

J Cell Sci. 2006 Jul 1;119(Pt 13):2635-41. Review.


Genome-wide linkage screen for testicular germ cell tumour susceptibility loci.

Crockford GP, Linger R, Hockley S, Dudakia D, Johnson L, Huddart R, Tucker K, Friedlander M, Phillips KA, Hogg D, Jewett MA, Lohynska R, Daugaard G, Richard S, Chompret A, Bonaïti-Pellié C, Heidenreich A, Albers P, Olah E, Geczi L, Bodrogi I, Ormiston WJ, Daly PA, Guilford P, Fosså SD, Heimdal K, Tjulandin SA, Liubchenko L, Stoll H, Weber W, Forman D, Oliver T, Einhorn L, McMaster M, Kramer J, Greene MH, Weber BL, Nathanson KL, Cortessis V, Easton DF, Bishop DT, Stratton MR, Rapley EA.

Hum Mol Genet. 2006 Feb 1;15(3):443-51. Epub 2006 Jan 11.


The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours.

Youngren KK, Coveney D, Peng X, Bhattacharya C, Schmidt LS, Nickerson ML, Lamb BT, Deng JM, Behringer RR, Capel B, Rubin EM, Nadeau JH, Matin A.

Nature. 2005 May 19;435(7040):360-4.

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